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Introductory Genetics
Chien-Ming Li MD, PhD
The male reproductive system
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Sex chromosome: XY, the 23rd pair
SNY gene
Penis
Scrotum
– Epididymis
– Testis: sperm, without mitochondria
• Meiosis: N
The female reproductive system
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Sex chromosome: XX, the 23rd pair
Uterus
Fallopian tube
Ovary
Vagina
Cervix
Labia
Egg: meiosis, N, with mitochondria
Gregor Mendel: pea
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R gene: dominant
Red flower: RR or Rr
White flower: rr
RR x rr  Rr
Rr x Rr  RR: Rr: rr, 1:2:1
Central dogma
• DNA (in nucleus)  RNA  protein  function
• DNA
– Adenine (A)
– Thymine (T)
– Guanine (G)
– Cytosine (C)
• DNA: double helix, A-T, G-C