Acute Respiratory Distress Syndrome It’s so shocking, I can’t breathe! Heidi Ditmyer DVM University of Tennessee College of Veterinary Medicine Department of Pathobiology Tifton 2008 Presented at SEVPAC.
Download
Report
Transcript Acute Respiratory Distress Syndrome It’s so shocking, I can’t breathe! Heidi Ditmyer DVM University of Tennessee College of Veterinary Medicine Department of Pathobiology Tifton 2008 Presented at SEVPAC.
Acute Respiratory Distress
Syndrome
It’s so shocking, I can’t breathe!
Heidi Ditmyer DVM
University of Tennessee
College of Veterinary Medicine
Department of Pathobiology
Tifton 2008
Presented at SEVPAC 2008 –
Permission granted for use on
SEVPAC website only
Signalment
Juvenile Female Spayed Yorkshire Terrier
Presented to rDVM after chewing electric
cord
rDVM treated with Oxygen and diuretics
Presented at SEVPAC 2008 –
Permission granted for use on
SEVPAC website only
Case 07-796
Referred to UT
Ventilator
Febrile
Died 24 hours post arrival
Presented at SEVPAC 2008 –
Permission granted for use on
SEVPAC website only
Gross Findings
Glossal and gingival ulceration
Bilateral interstitial pneumonia
Congenital portosystemic shunt
Presented at SEVPAC 2008 –
Permission granted for use on
SEVPAC website only
Glossal ulceration
Presented at SEVPAC 2008 –
Permission granted for use on
SEVPAC website only
Presented at SEVPAC 2008 –
Permission granted for use on
SEVPAC website only
Presented at SEVPAC 2008 –
Permission granted for use on
SEVPAC website only
Histology and etiology
Fibrinous interstitial pneumonia
Multiple possibilities
Consistent with Acute Respiratory Distress
Syndrome
Presented at SEVPAC 2008 –
Permission granted for use on
SEVPAC website only
Acute Respiratory Distress
Syndrome (ARDS)
Acute onset
Bilateral/diffuse pulmonary changes
Hypoxemia
No evidence of left atrial hypertension
Presented at SEVPAC 2008 –
Permission granted for use on
SEVPAC website only
ARDS
Secondary inflammatory response
Macrophages cytokines enzymes
free radicals diffuse alveolar and
endothelial damage
Differential diagnosis for any animal with
non-cardiogenic pulmonary edema and
appropriate risk factors
Presented at SEVPAC 2008 –
Permission granted for use on
SEVPAC website only
Conclusion
Limited lung response regardless of trigger
Overzealous inflammatory response
Pathophysiology not entirely understood
Considered as differential diagnosis
Presented at SEVPAC 2008 –
Permission granted for use on
SEVPAC website only
Acknowledgements
Dr Kim Newkirk
UT histology staff
Presented at SEVPAC 2008 –
Permission granted for use on
SEVPAC website only
Thank you
www.k9station.com
Questions?
Presented at SEVPAC 2008 –
Permission granted for use on
SEVPAC website only