Transcript Welcome CTSA Grand Rounds

Welcome
Master’s Degree Orientation
May 2, 2013
Center for
Translational Science Activities
Educational Resources
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Agenda
• Introductions
• CTSA Program Overview
• Master’s Degree Requirements
• Research Proposal
• Scholar/Mentor Relationships
• Competencies
• Program Evaluations & Outcomes
• Questions
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CTSA Executive Committee
External Advisory
Committee
Scientific
Review Panels
Robert A. Rizza, MD
Mayo Clinic Director for Research
CTSA Director and Principal Investigator
Internal Advisory
Committee
Novel
Methodology
David O. Warner, MD
Mayo Clinic Associate Director for Clinical/Translational Research
CTSA Associate Director and Co-PI
CTSA Academic Affairs
Committee
Pilot and
Feasibility
Scott Kaese / Jane C. Welter
Administrators, Mayo Clinic Research Administrative Services
CTSA Director / Associate Director of Administration
Communications
Education
Resources
Research
Resources
D. Warner, MD
S. Khosla, MD
Co-PI and Director
Co-PI and Director
Predoctoral
Programs
Postdoctoral
Programs
Research
Management
Programs
Medical
Student
Programs
CTS Masters
and Certificate
Programs
PhD & MD/PhD
Program in CTS
KL2 Mentored
Career Devel
Program
Study
Coordinator
Degree
and Diploma
Programs
Continuous
Professional
Development
Program
Research Resources
Review Panel (RRRP)
Consultative,
Regulatory, and
Informatics Services
P. Targonski, MD PhD R. D. Simari, MD
Community
Engagement
Co-PI and Director
Clinical
Research
Unit (CRU)
Saint Marys
Charlton
Mobile
Translational
Technology
Cores (TTC)
Specialized
Phenotyping
Facilities
Scholarly Opportunity
Award
Co-PI and Director
CommunityBased Research
Networks
Regulatory
Support
Res. Subject
Advocacy
Services
Translating
Comparative
Effectiveness
Research into
Practice
(TRACER)
Biomedical
Informatics
Research
Ethics
Resource
Office for
Community
Engaged
Research
(OCER)
Study
Design and
Biostatistics
Research
Information
Center
Research
Volunteer
Resource (RVR)
03/27/13
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Mayo Clinic
Center for Translational Science Activities (CTSA)
• CTSA Research Resources (CRU)
• CTSA Community Engagement
• CTSA Consultative, Regulatory and Informatics Services
• CTSA Education Resources –
David O. Warner, MD, Director
Glenn E. Smith, PhD, LP, Associate Director
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Postdoctoral Administrative Staff
• W. Ray Kim, M.D.
• Director, Postdoctoral Programs
• Shawna L. Ehlers, Ph.D., L.P.
• Associate Director, Postdoctoral Programs
• Katrin Frimannsdottir, Ph.D.
• Director of Program Evaluation
• Karen Weavers – Operations Manager
• Tauna Juengers – Operations Coordinator
• Anne Bofferding – Curriculum Manager
• Linda Wenner –Program Coordinator – Master’s
• Linda Ramaker – Program Coordinator- Master’s
• Ashley Noelke– Administrative Assistant
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CTSA Master’s Degree Program
Goal:
To train independent investigators to perform
outstanding extramurally-funded patient-based
research.
The Social Contract of Medical Research
(discovering and applying knowledge to improve health)
is a privilege.
AAMC-GREAT Group
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Master’s Degree Program Expectations
• Find time for coursework:
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1 hr. lecture = 2-4 hours outside work
1 credit = 48 hours/qtr or 4 hours/week
3 cr/qtr ~ 12 hours/week
Aligned with research goals
• Accept feedback from mentors/tutors/peers
• Learn to identify the important questions
• Take charge of your destiny
• Submit by deadlines indicated
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Master’s Degree Program Requirements

24 credits - 3.0 GPA
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16 required CTSC
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8 elective (either CTSC or MGS)
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Comprehensive Written Examination (fullday)
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Mentored research project resulting in a
thesis (2-3 papers – CITE THE GRANT!)

Final Oral Examination (thesis defense)

Can be completed in 2-3 years
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Required Coursework
5600-Statistics in Clinical
Research (2)
5601-Utilizing Statistics in Clinical
Research (1)
5610-Introductory Stats Methods
II (3)
5690-Critical Appraisal of
Statistical Methods in the Medical
Literature (1)
5300 & 5310-Clinical
Epidemiology I & II (1 ea)
5010-Clinical Research Protocol
Development (2)
6000-Responsible Conduct of
Research (1)
5720-Clinical Trials: Design and
Conduct (1)
5020-Regulatory Issues in Clinical
Research (1)
Grant Writing Wksp – Nov. 8, 2013
Publication Wksp - Mar. 6, 2014
5390- Advanced Applied
Epidemiological Methods (2)
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Potential Elective Courses
Clinical Trials
Behavioral
Individualized
Medicine
Health Care
Delivery
• CTSC 5640 Logistic Regression
• CTSC 5650 Survival Analysis
• MPET 6820 Regenerative Medicine
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CTSC
CTSC
CTSC
CTSC
5080 Eliminating Health Disparities
5810 Qualitative Research Design
5860 Behavioral Interventions in Clinic Research
5870 Social & Behavioral Foundations of Health in HSR
• BMB 8350 Intro to Bioinformatics
• CTSC 5140 Epigenetics and Epigenomics
• CTSC 5660 Design analysis & App of Bioinformatics
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CTSC 5960 Medical Informatics
CTSC 5760 Medical Decision Making
CTSC 5761 Evidence Based Medicine for Clinical Researchers
CTSC 5910 Economic Evaluation in Health Care
CTSC 5940 Secondary Data Analysis
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Coursework
• Required: 7 credits beginning either summer
or winter quarter
• Mayo Graduate School Course Information
• CTSA Annual Course Schedule
• Courses available in-person and online
• Registration begins one month prior to each
quarter
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Workshops
 Writing for Biomedical Publications
• March 6, 2014 ~ offered once per year only
• Available at all three sites (MCR, MCA, MCF)
• Registration Fee - $275 (fee waived)
 Write Winning Grants
• November 8, 2013 ~ offered once per year only
• Available at all three sites (MCR, MCA, MCF)
• Registration Fee - $275 (fee waived)
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Research Proposal Packet
(due Jan. 2, 2014)
• Includes:
1) Cover page (new)
2) Cover letter signed by you and your mentor
3) Research Proposal Format
4) Division research committee approval
5) IRB approval
• Reviewed using the Research Proposal Review Criteria
• Submission cycle to CTSA approval is twice each year
• January or July only
• Early submissions are accepted
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Thesis Advisory Committee (TAC)
(due Jan. 2, 2014)
• Minimum of 4 members –
1) Thesis Advisory Committee (TAC) Form
2) Recommended Action on Thesis Protocol Form
• TAC and scholar have defined roles and expectations
• Chair - usually primary mentor – only member who can also be coinvestigator (exception for statistician)
• Members - need MGS Faculty Privileges (check Catalog)
• Oversees progress and quality of research project
• Meet every 6 months to review progress of scholar
• Submit summary of Progress Report Meetings to CTSA
• Becomes Examining Committee at Thesis Defense
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Master’s Degree Program Form (DPF)
(due Jan. 2, 2014)
• Include courses you propose to take to fulfill degree
requirements (24 credits total; 17 required)
• Can transfer in up to 6 credits (25%) and may require a
taking a test
• Master’s Degree Program Form on Mayo Graduate
School Web site
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Comprehensive Written Exam
• Taken after completion of (14 cr):
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Protocol Development
Epi I & II
Advanced Applied Epi (III)
Stats I & II
Critical App of Stat Methods (III)
Clinical Trials Design
• Full day exam
• August 20, 2013, January 21 or April 15, 2014
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Final Oral Examination –
Thesis Defense
• After completion of all course work, approval of DPF, research
proposal and TAC and Comprehensive Written Exam
• Follow CTSA and MGS Thesis Guidelines
• Project thesis defense date include on Cover Page. Modifications
to date will be communicated through Progress Report Summaries
• Six weeks prior to your anticipated defense date –
• Submit thesis draft for CTSA review (allow 1 week)
• Find a date/time all TAC members will be present
• Allow 3 weeks for TAC to review final draft and prepare
examination questions
• After successful defense, submit Verification of Thesis Corrections
and Final thesis to Mayo Graduate School
• Complete Evaluations
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Program Timeline
• January 2, 2014:
• Research Proposal Packet (5 items)
• Thesis Advisory Packet (2 items)
• Degree Program Form (1 item)
• November 8, 2013 – Write Winning Grants Workshop
• March 6, 2014 – Publishing Workshop
• April 15, 2014 – Comprehensive Written Exam (potential)
• July 1, 2014 – Progress Report due
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Scholar and Mentor Relationships
Expectations
These are meant as a guide to help facilitate optimal scholar/mentor
relationships. Contact CTSA if questions arise.
1) Initial Agreement – at time of application
2) Progress Report – submitted 6 months
after research proposal is approved
3) Mentoring Effectiveness Assessment
(Scholar & Mentor) – will be requested
annually, spring quarter.
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Competencies
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Critically evaluate clinical/translational research in the
medical literature
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Articulate the ethical & legal responsibilities of an
investigator
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Develop feasible and testable hypotheses
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Design and conduct a clinical/translational research
project
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Write competitive grant proposals
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Effectively communicate research results through
publication
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Effectively communicate research results through
presentation
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Competencies (cont.)
•
Articulate and apply appropriate study designs
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Use appropriate biostatistical methods
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Understand the peer-review process
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Ability to navigate the peer-review process for grants
and papers
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Program Evaluations & Outcomes
Program Evaluation Activities
• Clinical Translational Research Appraisal
(CTRAI) Pre/Post self-assessment –
completed in CTSC 5300 Epi I and at end of program
• Mentor Assessments – annual
• Course Evaluations
• Graduate tracking – annual CVs
Publications, grants, promotions, awards, patents,
leadership and professional activities, etc.
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Websites to know
CTSA Education Resources
http://ctsa.mayo.edu/education/index.html
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Quarterly Course Schedule
Program Milestones
New course listings
This presentation
Mayo Graduate School
http://mayoweb.mayo.edu/mgs/
• Quarterly course listing
• Course Registration
• Other required forms
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“The research we do today will determine
the type of medical and surgical practice
we carry on at the Clinic tomorrow.”
-William J. Mayo, M.D.
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