abbreviations.

Download Report

Transcript abbreviations.

Abbreviations
abbreviations.
ADP – adenosine diphosphate
AKAP – A-kinase anchoring protein
AMP – adenosine monophosphate
AMT – amoeboid-mesenchymal transition
ANOVA – analysis of variance
APC – adenomatosis polyposis coli
Arp2/3 – actin related protein 2/3
atRA – all-trans retinoic acid
BrdU – bromodeoxyuridine
BSA – bovine serum albumin
CBP – CREB-binding protein
Cdc42 – cell division control protein 42 homolog
CK1 – casein kinase 1
CREB – cyclic AMP response element binding
COG – Children’s Oncology Group
COX-1/2 – cyclooxygenase 1/2
CRAB – cellular retinoic acid binding protein
CXCR4 – C-X-C Motif Chemokine Receptor 4
Daam1 – DVL-associated activator of morphogenesis 1DAB – 3,3'-diaminobenzidine
DEP – disheveled, Egl-10 and pleckstrin domain DLC1/2/3 – deleted in liver cancer 1/2/3
DMEM – Dulbecco’s modified eagle’s medium DOCK2 – dedicator of cytokinesis 2
DVL – disheveled
ECL – enhanced chemiluminescence
ECM – extracellular matrix
EDTA – Ethylenediaminetetraacetic acid
ELISA – enzyme-linked immunosorbent assay
EMT – epithelial-mesenchymal transition
EP1/2/3/4 – E-type prostanoid receptor 1/2/3/4
Epac1/2 – exchange protein directly activated by cyclic AMP 1/2 ERK – extracellular signal-regulated kinase
ET1 – endothelin 1
FACS – fluorescence activated cell sorting
FCS – fetal calf serum
FISH – Fluorescence in-situ hybridization
FITC – Fluorescein isothiocyanate
FRET – fluorescence resonance energy transfer
Fzd – Frizzled family receptor
218
Abbreviations
GAP – GTPase activating protein
GAPDH – glyceraldehyde 3-phosphate dehydrogenase
GDI – guanine nucleotide dissociation inhibitor
GDP – guanine diphosphate
GEF – guanine exchange factor
GPCR – G-protein coupled receptor
GSK-3 – glycogen synthase kinase 3
GTP – guanine triphosphate
HBSS – Hank’s balanced salt solution
HDAC – histone deacetylase
HEPES – 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid
Hif1α – hypoxia inducible factor 1α
HMGCR – 3-hydroxy-3-methylglutaryl-coenzyme A reductase
HRE – hypoxia response element
HRP – horseradish peroxidase
IBMX – 3-isobutyl-1-methylxanthine
IDV – integrated density value
IQGAP – IQ motif containing GAP
LARG – leukemia-associated Rho GEF
LATS1/2 – large tumor suppressor kinase 1/2
LEF – lymphoid enhancer-binding factor 1
LRP5/6 – low-density lipoprotein receptor-related protein 5/6
LIMK – Lin11, Isl-1 & Mec-3 (LIM) domain kinase
MAT – mesenchymal-amoeboid transition
mDia – diaphanous-related formin
MLC – myosin light chain
MLCK – MLC kinase
MMP – matrix metalloprotease
MRCK – myotonic dystrophy-related Cdc42-binding kinase
MRTF-A – myocardin-related transcription factor A
MYCN – v-Myc avian myelocytomatosis viral oncogene neuroblastoma
NET1 – neuroepithelial cell transforming 1
NSAID – non-steroid anti-inflammatory drug
NSCLC – non-small cell lung carcinoma
N-WASP – neural Wiskott-Aldrich syndrome protein
PAK – p21-activated kinase
PARP – poly(ADP)-ribosylating polymerases
PBS – phosphate-buffered saline
PDE – phosphodiesterase
PFA – paraformaldehyde
PDK1 – 3-phosphoinositide-dependent protein kinase 1
PDZ – PSD95, Dlg1, and ZO-1 domain
PGE2 – prostaglandin E2
PI – propidium iodide
219
Abbreviations
PI3K – phosphoinositide 3-kinase
PKA – protein kinase A
PKC – protein kinase C
PLD1 – phospholipase D1
PMSF – phenylmethylsulfonyl fluoride
PTK7 – protein tyrosine kinase 7
pVHL – von Hippel-Lindau protein
qPCR – quantitative polymerase chain reaction
RAR – retinoic acid receptor
RARE – retinoic acid response element
RGS – regulator of G-protein signaling
Rac – ras-related C3 botulinum toxin substrate RanBP2 – ran-binding protein 2
Rap – Ras-proximate
RB – retinoblastoma-associated
Rho – ras homolog gene family
RIPA – radioimmunoprecipitation assay buffer
ROCK – rho-associated, coiled-coil-containing protein kinase
ROI – region of interest
ROR2 – receptor tyrosine kinase like orphan receptor 2
RPMI 1640 – Roswell park memorial institute 1640 medium
RXR – retinoic acid X receptor
RYK – receptor like tyrosine kinase
RyR – ryanodine receptor
S1P – sphingosine 1 phosphate
SDF1 – stromal cell-derived factor 1
SDS-PAGE – sodium dodecyl sulfate polyacrylamide gel electrophoresis SEM – standard error of the mean
Smurf1 – SMAD specific E3 ubiquitin protein ligase 1
SOCE – store operated calcium entry
Sra1 – steroid receptor RNA activator 1
SRF – serum response factor
TBS – tris-buffered saline
TCF – transcription factor family
TEAD – transcriptional enhancer factor domain
TEM4 – tumor endothelial marker 4
TGF-β – transforming growth factor β
Tiam – T-cell lymphoma invasion and metastasis
TP53 – tumor protein p53
Trio – triple functional domain protein
VEGF – vascular endothelial growth factor
WAVE – WASP-family verprolin-homologous protein
Wnt – wingless-type MMTV integration site family member
WRC – WAVE regulatory complex
YAP – yes-associated protein
ZEB1 – zinc finger E-box binding homeobox 1
220