Are you PrEPed?: Exploring New HIV Prevention Tools Presented by: Monica Ramirez and Joaquin Gutierrez.
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Are you PrEPed?: Exploring New HIV Prevention Tools Presented by: Monica Ramirez and Joaquin Gutierrez PrEP Objectives • AltaMed Health Services • Discuss HIV Prevention Methods – Then, Now, & Future • What is PrEP? What is PEP? Is there a Difference? • Speaking to clients about PrEP and PEP • Discuss access to PrEP and PEP 2 AltaMed Health Services Mission: To eliminate disparities in health care access and outcomes by providing superior quality health and human services through an integrated world-class delivery system for Latino, multi-ethnic and underserved communities in Southern California. 3 AltaMed Programs & Services • • • • • • • • • Primary Care Women's Health and Children's Specialty Senior Services Dental Services HIV Testing and HIV Medical Care Health Education Chronic Care Support Youth Programs Drug Treatment / Prevention Pharmacy 4 AltaMed’s Physical Locations HIV Specialty Clinic & Storefront Testing Location • 2 sites located in East Los Angeles, 1 in Orange County • 2 satellite clinics in Pico Rivera and El Monte 5 PrEP HIV Prevention Tool Box 6 PrEP What is PrEP? 7 PrEP What is PrEP? PrEP = Pre-Exposure Prophylaxis • Approved in 2012 for Prevention • Involves taking anti-retroviral medications daily to reduce risk of infection BEFORE HIV exposure • PrEP prevents HIV from replicating in the body • Truvada® as PrEP • One pill • Once daily • Every day 8 PrEP Initial Medical Visit • • • • • • Health Physical HIV test STI exam Blood draw for Kidney and Liver function Risk behaviors Prescription is given 9 PrEP FOLLOW-UP VISITS • • • • • • Medical Visits every 3 months HIV test STI test Blood draw to see how body is reacting to Truvada Counseling on sexual behaviors Treatment Adherence 10 PrEP Medical Visits Side effects • Upset stomach • Loss of appetite • Mild Headaches Usually only reported in the first month of taking PrEP 11 PrEP What does PrEP not do? • Protect against other STD’s • Prevent pregnancy • Function as treatment for someone living with HIV already • Cure HIV • Like most prevention methods, does not offer100% protection from HIV infection 12 PrEP PrEP RESEARCH • PrEP only works if taken • High adherence achieved 90%+ reduction in risk • Truvada PrEP trials to date have not shown increases in sexual risk behavior among • participants Across all PrEP studies of Truvada, there have been no serious safety problems so far 13 PrEP How do you access PrEP? • Any MD, DO, PA, or NP can prescribe Truvada • PrEP is covered by most third-party insurance plans and also covered through Medi-Cal • Clinic-based studies being done in Los Angeles County provide Truvada at no cost • Gilead patient assistance program: www.truvada.com • Drug Provision • Co-Payment Assistance • Lab cost reimbursement (HIV & HBV) 14 PrEP MOTIVATIONAL INTERVIEWING • • • • • Non-judgmental Identifying and discuss discrepancies Roll with resistance Promote Self-Efficacy Implementing a Treatment Adherence Plan 15 PrEP Who benefit from PrEP? • Discordant couples • Clients who have used PEP • People who can’t use condoms • Individuals who don’t want to use condoms • IDU- intravenous drug users • People who think they could benefit 16 PEP WHAT IS PEP? 17 PEP WHAT IS PEP? • • • Post-Exposure Prophylaxis Prophylaxis is any way to prevent, rather than treat or cure a disease • • • • In current approved form, PEP is either a combo of 2 or 3 antiretroviral drugs • 2 drug regimen – Truvada (tenofovir + emtricitabine) • 3 drug regimen – Truvada and Isentress (raltegravir) Used as HIV prevention within 72 hours of potential exposure Medication must be taken for 28 days after potential exposure PEP users must get HIV testing at 4 to 6 weeks, 3 months, and 6 months after the potential exposure Source: CDC, PEP 101 18 PEP HOW DO WE KNOW PEP WORKS? • PEP originally approved in 1996 for health care workers exposed to HIV through job • PEP reduced the rate of HIV infection from workplace exposures by 79%.* • In 2005, CDC approved PEP for non-work HIV exposure. • Specific drugs used in PEP have changed as more effective medications become available. Source: AIDS.org • Other sources of data on PEP efficacy: • From animal transmission models • Perinatal clinical trials • Studies of health-care workers receiving ARVs after occupational exposures • Observational studies 19 PrEP SIDE EFFECTS OF PEP • PEP can cause diarrhea, headaches, nausea and vomiting. • These side effects stop once you have finished taking the drugs or after first week of taking PEP. • One Australian study revealed that 2 out of 3 people taking PEP experienced mild to moderate side effects and 1 in 4 people taking PEP experienced severe side effects. 20 PEP HOW DO CLIENTS ACCESS PEP? Emergency Rooms • Any Emergency Room can provide PEP • However, ERs usually only provide 3 days of medication (a“starter pack”) Primary Care Providers • Any doctor can prescribe • Accessing in 72 hour window can be a challenge • Staying engaged for testing period also can be difficult (HIV test at 4-6 wks, 3 mos, 6 mos required) HIV Agencies • OASIS Clinic (Free) • LA LGBT Center (Free) 21 PrEP ACCESSING PEP IN LOS ANGELES COUNTY • Los Angeles LGBT Center – Jeffrey Goodman Clinic – 1625 N. Schrader Blvd. Los Angeles 90028 – Phone: 323-860-5855 – [email protected] – http://www.lalgbtcenter.org/post_exposure_pro phylaxis_pep 22 PEP MEDICAL VISIT • Risk Assessment • HIV Test • Provided Prescription • Follow-Up appointment with Provider 23 PrEP HOW MUCH DOES PEP COST? • Can cost $1,000 + for the 28-day treatment • Insurance can cover • Medicaid coverage inconsistent • Pharmaceutical corporation access programs can help • State Office for Victims of Crime can pay for sexual assault survivors • CalVCP Helpline: 1-800-777-9229 24 PEP PATIENT ASSISTANCE PROGRAMS for PEP 25 PEP PATIENT ASSISTANCE PROGRAMS FOR PEP 26 PEP PATIENT ASSISTANCE PROGRAMS FOR PEP 27 PEP TOOLS FOR PEP EDUCATION TALK PEP Campaign • Social marketing campaign by Fenway Health to increase knowledge of PEP among gay and bisexual men in Boston. • Common reasons for potential exposure to HIV, used to catch audience attention • Graphics & videos accessible free of charge http://talkpep.org/ 28 PEP TOOLS FOR PEP EDUCATION • Centers for Disease Control & Prevention – PEP 101 http://www.cdc.gov/hiv/basics/pep.html – PEP for Non-Work Exposure Guidelines (2005) http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5402a1.htm – PEP for Work Exposure Guidelines (2005) http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5409a1.htm • • http://publichealth.lacounty.gov/dhsp/PEP-Provider.htm http://www.avert.org/post-exposure-prophylaxis-pep.htm • AIDS.gov – POST-EXPOSURE PROPHYLAXIS http://aids.gov/hiv-aids-basics/prevention/reduce-your-risk/post-exposureprophylaxis/ 29 PrEP and PEP TREATMENT ADHERENCE TIPS How can I remember to take my medication? • Take your medications at the same time you brush your teeth morning and night - and place the medications near your toothbrush so you will notice them. • Set the alarm on your mobile phone to remind you to take your medications • Get someone you trust to remind you to take your medications 30 HIV PREVENTION TOOLS Condoms PrEP PEP 31 Contact Information THANK YOU Monica Ramirez HIV Prevention Supervisor 323-307-0137 [email protected] Joaquin Gutierrez HIV Prevention Specialist 323-307-0131 [email protected] 32