PowerPoint Presentation - Vanderbilt University Medical Center

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Regulatory Compliance Analyst, Clinical
The Buffalo General Hospital School of Nursing,
the second oldest school for nurses in the United
States, was organized in 1877.
Adult Education and Training
Staff Nurse 1979 - 1983
Vanderbilt University Medical Center
Research Nurse – 1983 - 1986
Research Nurse – 1986 - 2006
Vanderbilt University School of Medicine
Research Services Consultant – 2006-2011
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Regulatory Compliance Analyst, Clinical
2011 - Present
Publications:
Fitzgerald DJ, Mayo G, Catella F, Entman SS, FitzGerald GA. Increased thromboxane
biosynthesis in normal pregnancy is mainly derived from platelets. Am J Obstet Gynecol.,
157:325-30, 1987.
FitzGerald GA, Mayo G, Price P, Takahara K. Aspirin in cardiovascular disease; biochemical
pharmacology and clinical trials. Prog Clin Biol Res., 301:97-106, 1989.
Fitzgerald DJ, Rocki W, Murray R, Mayo G, FitzGerald GA. Thromboxane A2 synthesis in
pregnancy-induced hypertension. Lancet, 335:751-754, 1990.
Clarke RJ, Mayo G, FitzGerald GA, Fitzgerald DJ. Combined administration of aspirin and a
specific thrombin inhibitor in man. Circulation, 83:1510-8, 1991.
Clarke RJ, Mayo G, Price P, FitzGerald GA. Suppression of thromboxane A2 but not of
systemic prostacyclin by controlled-release aspirin. N Engl J Med., 325:1137-41, 1991.
Keimowitz RM, Pulvermacher G, Mayo G, Fitzgerald DJ. Transdermal modification of platelet
function. A dermal aspirin preparation selectively inhibits platelet cyclooxygenase and
preserves prostacyclin biosynthesis. Circulation, 88:556-61,1993.
Publications Continued
Sofowora GG, Choo EF, Mayo G, and Wilkinson GR. In vivo inhibition of human CYP1A2
activity by oltipraz. Cancer Chemotherap. Pharmacol., 47:505-510, 2001.
Floyd MD, Gervasini G, Masica AL, Mayo G, George AE, Bhat K, Kim RB, and Wilkinson GR.
Genotype-phenotype associations for common CYP3A4 and CYP3A5 variants in the basal and
induced metabolism of midazolam in European- and African-American men and women.
Pharmacogenetics, 13:595-606, 2003.
Takahashi H, Leiri L, Wilkinson GR, Mayo G, Kashima T, Kimura S, Otsubo K, Echizen H. 5’Flanking region polymorphisms of CYP2C9 and their relationship to S-warfarin metabolism in
white and Japanese patients. Blood, 103(8):3055-7, 2004.
Masica AL, Mayo G, and Wilkinson GR: In vivo measurement of constitutive CYP3A activity
assessed by alprazolam, triazolam and midazolam. Clin. Pharmacol. Therap., 76: 341-349,
2004.
Schwarz UI, Johnston PE, Bailey DG, Kim RB, Mayo G, Milstone A. Impact of citrus soft drinks
relative to grapefruit juice on ciclosporin disposition. Br J Clin Pharmacology, 62(4):485-91,
2006.
Publications Continued
Ho RH, Choi L, Lee W, Mayo G, Schwarz UI, Tirona RG, Bailey DG, Stein, MC, Kim RB. Effect of
drug transporter genotypes on pravastatin disposition in European and African-American
participants. Pharmacogenet Genomics. 17(8):647-56, 2007.
Haas DW, Gebretsadik T, Mayo G, Menon UN, Acosta EP, Shintani A, Floyd M, Stein CM,
Wilkinson, GR. Associations between CYP2B6 polymorphisms and pharmacokinetics after a
single dose of nevirapine or efavirenz in African Americans. J Infectious Disease, 199(6):87280, 2009.
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