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The Role of Blood Donation in Healthcare

Presented by Peter Hudson Clinical Specialist in Blood Transfusion

WHERE DO WE GET OUR BLOOD SUPPLIES FROM?

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UK sourced from voluntary unpaid donors

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Collected and processed by the National Blood Service

WHY GIVE BLOOD?

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Over 35,000 donations weekly

- 1.4 million donors - Only 4% of people give blood

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10-15% donor loss per year

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Donors don’t give every time

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Constantly “topping-up”

WHO ARE THE NATIONAL BLOOD SERVICE?

 Part of the National Health Service  Provide blood and blood products to hospitals

A BRIEF HISTORY OF BLOOD DONATION

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1666:

First successful blood transfusion •

1900:

Four Human blood types discovered •

1946:

National Blood Service Launched

SO WHAT EXACTLY IS BLOOD?

• Transfers oxygen from the lungs • Communication System within body • Average person has 5 litres of blood

COMPONENTS AND THEIR ROLES

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Red Cells

- Distribute oxygen and nutrients - Contain haemoglobin

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White Cells

- Fight infection - Several different types

COMPONENTS AND THEIR ROLES

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Platelets

Form a “plug” to stop bleeding - 5 day shelf-life

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Plasma

- Carries other blood cells - Carries Albumin and Factor Viii

BLOOD TYPES

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A, B, AB and O

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Antigens

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A and B antigens Rh Antigen

BLOOD TYPES

BLOOD AROUND THE WORLD

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Prevalence varies across the world

- B more common in South Asian people than Westerners - Anthropology

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Some blood conditions are more common in different communities

- Sickle Cell Anaemia and Thalassemia - Events of the past, e.g. plague

WHO NEEDS BLOOD?

Gastro intestinal bleeding 11% General surgery 10% Haematology 15% •

How many units get used?

- Open heart surgery = 2-8 red cell units, 6 platelet units - Car accident = 4-40 red cell units Orthopaedics 14% Anaemia 23%

RECIPIENT STORIES BROOKE CORNWELL

• 2 years old – has received 27 units of blood • Has Diamond Blackfan Anaemia • Needs blood every month to live

RECIPIENT STORIES LUKE CRAIG

• Involved in a horrific car crash • Internal bleeding and tear in his heart • Emergency operation – 24 units of blood

RECIPIENT STORIES MIKE AUSTIN

• Severe motorbike accident • Leg destroyed – artery damaged • Received 33 units of blood

RECIPIENT STORIES AWELE NWOSU-AKEH

• 17 year old with Sickle Cell Anaemia • Receives blood every 4 weeks • Blood allows her to have a normal life

RECIPIENT STORIES KEIRA

• Kostmann’s syndrome • Bowel removed • 9 units of red cells and 7 of platelets

RECIPIENT STORIES NISA HEYS

• Has Thalassaemia Major • Has transfusions every 3 weeks • Received over 1300 units of blood so far

CAN YOU DONATE?

• You must be aged between 17-65 to donate for the first time • Most common criteria we check are: - Tattoos - Piercings - Travel - Medication • You will always be asked to fill out a Donor Health Check questionnaire

CAN YOU DONATE? (MYTHS)

“

I could die as a result of donation

” “ I might catch something ” “

You don’t want my blood

” “You experiment on our blood” “ It hurts ”!

“ I ALWAYS faint ”!

“ I smoke and drink alcohol ”

THE DONATION PROCESS

Making the call Fill out the questionnaire Arrive at session The donation Aftercare

DONOR ETHNICITY

White Mixed South Asian African & Caribbean Chinese Any Other Group “25% of the South Asian ethnic population are blood group B and only 9% of Western Europeans share this group”

DONOR ETHNICITY (cont)

• We need to build the British Bone Marrow Registry • Some tissue types are specific to certain ethnic groups of the population • The notion of blood donation does not enter personal and social spheres

British Bone Marrow Register

WHAT HAPPENS TO THE BLOOD?

• Kept cool then collected • Typed and tested • Components Separated • Banked and ready to go!

WHAT IS THE BLOOD TESTED FOR?

VIRUSES HIV 1 and 2 Hepatitis B Virus (HBV) Hepatitis C Virus (HBC) HTLV (Human T- cell Leukaemia Virus) Cytomegalovirus (CMV)

THEY DON’T JUST COLLECT BLOOD

• Bone Marrow • Organs • Cord Blood • Tissue

THANK YOU FOR LISTENING

Any Questions?