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The Role of Blood Donation in Healthcare

Presented by Peter Hudson Clinical Specialist in Blood Transfusion

WHERE DO WE GET OUR BLOOD SUPPLIES FROM?

UK sourced from voluntary unpaid donors

Collected and processed by the National Blood Service

WHY GIVE BLOOD?

Over 35,000 donations weekly

- 1.4 million donors - Only 4% of people give blood

10-15% donor loss per year

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Donors don’t give every time

-

Constantly “topping-up”

WHO ARE THE NATIONAL BLOOD SERVICE?

 Part of the National Health Service  Provide blood and blood products to hospitals

A BRIEF HISTORY OF BLOOD DONATION

1666:

First successful blood transfusion •

1900:

Four Human blood types discovered •

1946:

National Blood Service Launched

SO WHAT EXACTLY IS BLOOD?

• Transfers oxygen from the lungs • Communication System within body • Average person has 5 litres of blood

COMPONENTS AND THEIR ROLES

Red Cells

- Distribute oxygen and nutrients - Contain haemoglobin

White Cells

- Fight infection - Several different types

COMPONENTS AND THEIR ROLES

Platelets

Form a “plug” to stop bleeding - 5 day shelf-life

Plasma

- Carries other blood cells - Carries Albumin and Factor Viii

BLOOD TYPES

A, B, AB and O

Antigens

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A and B antigens Rh Antigen

BLOOD TYPES

BLOOD AROUND THE WORLD

Prevalence varies across the world

- B more common in South Asian people than Westerners - Anthropology

Some blood conditions are more common in different communities

- Sickle Cell Anaemia and Thalassemia - Events of the past, e.g. plague

WHO NEEDS BLOOD?

Gastro intestinal bleeding 11% General surgery 10% Haematology 15% •

How many units get used?

- Open heart surgery = 2-8 red cell units, 6 platelet units - Car accident = 4-40 red cell units Orthopaedics 14% Anaemia 23%

RECIPIENT STORIES BROOKE CORNWELL

• 2 years old – has received 27 units of blood • Has Diamond Blackfan Anaemia • Needs blood every month to live

RECIPIENT STORIES LUKE CRAIG

• Involved in a horrific car crash • Internal bleeding and tear in his heart • Emergency operation – 24 units of blood

RECIPIENT STORIES MIKE AUSTIN

• Severe motorbike accident • Leg destroyed – artery damaged • Received 33 units of blood

RECIPIENT STORIES AWELE NWOSU-AKEH

• 17 year old with Sickle Cell Anaemia • Receives blood every 4 weeks • Blood allows her to have a normal life

RECIPIENT STORIES KEIRA

• Kostmann’s syndrome • Bowel removed • 9 units of red cells and 7 of platelets

RECIPIENT STORIES NISA HEYS

• Has Thalassaemia Major • Has transfusions every 3 weeks • Received over 1300 units of blood so far

CAN YOU DONATE?

• You must be aged between 17-65 to donate for the first time • Most common criteria we check are: - Tattoos - Piercings - Travel - Medication • You will always be asked to fill out a Donor Health Check questionnaire

CAN YOU DONATE? (MYTHS)

I could die as a result of donation

” “ I might catch something ” “

You don’t want my blood

” “You experiment on our blood” “ It hurts ”!

“ I ALWAYS faint ”!

“ I smoke and drink alcohol ”

THE DONATION PROCESS

Making the call Fill out the questionnaire Arrive at session The donation Aftercare

DONOR ETHNICITY

White Mixed South Asian African & Caribbean Chinese Any Other Group “25% of the South Asian ethnic population are blood group B and only 9% of Western Europeans share this group”

DONOR ETHNICITY (cont)

• We need to build the British Bone Marrow Registry • Some tissue types are specific to certain ethnic groups of the population • The notion of blood donation does not enter personal and social spheres

British Bone Marrow Register

WHAT HAPPENS TO THE BLOOD?

• Kept cool then collected • Typed and tested • Components Separated • Banked and ready to go!

WHAT IS THE BLOOD TESTED FOR?

VIRUSES HIV 1 and 2 Hepatitis B Virus (HBV) Hepatitis C Virus (HBC) HTLV (Human T- cell Leukaemia Virus) Cytomegalovirus (CMV)

THEY DON’T JUST COLLECT BLOOD

• Bone Marrow • Organs • Cord Blood • Tissue

THANK YOU FOR LISTENING

Any Questions?