Sleep Loss, Fatigue and Medical Training University Hospital Housestaff 1982-83 Susan M. Harding, MD Professor of Medicine Medical Director, Sleep-Wake Disorders Center University of Alabama at.

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Transcript Sleep Loss, Fatigue and Medical Training University Hospital Housestaff 1982-83 Susan M. Harding, MD Professor of Medicine Medical Director, Sleep-Wake Disorders Center University of Alabama at.

Sleep Loss, Fatigue and
Medical Training
University Hospital Housestaff 1982-83
Susan M. Harding, MD
Professor of Medicine
Medical Director, Sleep-Wake Disorders Center
University of Alabama at Birmingham
Learning Objectives
List factors that put you at risk for
sleepiness and fatigue.
Describe the impact of sleep loss on
residents’ personal and professional
lives.
Recognize signs of sleepiness and
fatigue in yourself and others. Adapt
alertness management tools and
strategies for yourself and your program.
Residency Training Over
Past 5 Decades
Call every other night
Call every 3rd night, then every 4th night
Work is more stressful
“Less sick” patients are out of the hospital
Heightened intensity of patient care
Lower margin for error
Constant paging interruptions disrupt work
flow
State of Sleepiness Prior to ACGME
Limiting Resident Work Hours
Rosen IM et al. Acad Med 2004; 79:407
Survey of 79 Internal Medicine residents at the
Univ of Pennsylvania, June 2001
34% experienced acute sleep deprivation
64% experienced chronic sleep deprivation
Dozing while performing work-related tasks
–
–
–
–
69% writing notes
61% reviewing medication lists
51% interpreting labs
46% writing orders
ACGME Work Hour Rules
Effective July 1, 2003
Restricts work hours to < 80 hrs/week avg
< 30 hours of continuous coverage at any
1 time
Should have 10 hours off between shifts
Stimulus – quality of care, but minimal
data was available linking fatigue to errors
Different people have different “inflection
points” concerning sleep deprivation
ACGME Work Hour Rules
Made everyone re-examine their
educational programs
Provided impetus to examine ways to
improve the system
Emphasizes the need for more effective
team work
Brought up continuity of care and transfer
of care issues with frequent “hand offs”
What happens after training?
ACGME Work Hour Rules:
Potential Stressors
Ryan J. Ann Intern Med 2005; 143:82
Increased number of patient hand offs
Cross coverage
Communication and team work
Increasing paperwork
Pressure to get done and get out
Rushing from task to task w/out time to think and
learn
Resident comraderie
“No, I’ve just come to start my overnight call. Why do you ask?”
ACP Internist, Jan 2009
Institute of Medicine’s (IOM)
Recommendations (at Congress’ Request)
December 2008
2003 ACGME
2008 IOM
Max hrs work per
week
80 hrs, over 4 wks
same
Max shift length
30 hrs--24 hrs + 6 hrs 30 hrs with …
for transitional and
- 16 hrs admitting, 5
education activities
hrs protected sleep
period between 10
pm and 8 am
- 16 hours if no
protected sleep
period
Max in-hospital oncall frequency
Every 3rd night, on
average
Every 3rd night, no
averaging
2003 ACGME
2008 IOM
Minimum time
10 hrs after shift
off between
length
scheduled shifts
10 hrs after day shift
12 hours after night
shift
14 hrs after extended
duty of 30 hrs and not
to return until 6 am of
the next day
Max frequency
of in-hospital
night shifts
Not addressed
4 nights max; 48 hrs
off after 3 or 4 nights of
consecutive duty
Mandatory time
off
4 days off per month
1 day (24 hrs) off per
1 day (24 hrs) off per wk, no averaging
wk, average over 4
5 days off per month
wks
1 (48 hr) off period per
month
2003 ACGME
2008 IOM
Emergency Rm
limits
12-hr shift limits, with
No change
at least an equivalent off
period be tween shifts
60-hr work wk with 12
additional hrs for
education
Limit on
exemptions
88 hrs with a sound
educational rationale
No change
Moonlighting
Internal moonlighting is
counted against 80-hr
wk limit
Internal and external
moonlighting counted
against 80 hr wkly
limit
All other duty limits
apply in combination
Cost of Implementing IOM’s
Recommendations
1.7 billion per yr (1/4 of cost is bringing noncompliant programs into compliance – 8.8% of
programs
Create and fill fulltime positions for:
–
–
–
–
–
229 nursing aides
45 laboratory technicians
320 licensed vocational nurses
5984 NPs or PAs
5001 attending physicians
OR…
- 8247 additional residency positions
“There are fundamental effects from
sleep loss which permeate
performance on virtually all cognitive
and sustained attention tasks”
Courtesy of
Journal for
Respiratory
Care
Practitioners,
Jun/Jul 1998
Regulation of Sleep and
Wakefulness
Homeostatic drive for sleep (previous
sleep amounts, duration of wakefulness)
Circadian influence (24 hour clock,
alertness peaks and troughs)
Environmental factors: feedback,
reinforcement, task
nature/length/complexity
Individual variables: motivation, emotional
context; physical activity; age, individual
variation sleep needs and vulnerability
Effects of Sleep Deprivation:
Experimental Settings
Neurobehavior impairment similar for short-term
(24-48 hrs) total sleep deprivation and chronic
partial sleep restriction (<6 hrs/night for > 1 week)
Sleep “debt”: Effects of chronic partial sleep loss
are cumulative; not reversed in a single night
Perception of sleepiness is less affected than
measured sleepiness
Circadian influence
Effects of Sleep Deprivation:
Experimental Findings
Mood universally affected
Impairment in vigilance, delayed and
immediate recall
Complex tasks and problem-solving
affected; performance deteriorates with
time-on-task; task duration; perseveration
and poor prioritization
Maintenance of accuracy at the expense of
speed
Effects of Sleep Deprivation:
Experimental Findings
Learning of new tasks compromised
Motivation affected
“Lapsing”: variability in task performance
related to interruption of sustained
attention from “microsleeps”
Variability in performance may be more
affected than average quality
Factors Increasing Fatigue
Prolonged wakefulness (>15 continuous
hrs)
Reduced or disrupted sleep
Shift variability
Volume and intensity of work
Sleep Restriction
Banks S, Dinges DF. J Clin Sleep Med 2007; 3:519
Inter-individual differences, BUT…
Sleepiness – dose response effect
Lapses of attention and vigilance on tasks
More errors on simulated driving
Response slowing
Spatial learning problems
Decrease in behavioral alertness with “microsleeps”
Psychomotor vigilance test performance impaired
Working memory performance impaired
Mood problems
Cognitive and executive function impairment
Sleep Restriction
Banks S, Dinges DF. J Clin Sleep Med 2007;3:519
Physiological consequences…
Elevated BP
Reduced glucose tolerance
Sympathetic nervous system activation
Reduced leptin levels (appetite)
Increased inflammatory markers (IL-6,
TNFα, CRP)
Obesity
Sleep Restriction
Banks S, Dinges DF. J Clin Sleep Med 2007;3:519
Obesity
Insulin resistance
Cardiovascular events (epidemiological
studies)
Mortality
Common cold susceptibility (Cohen S et al.
Arch Intern Med 2009;169:62)
Sleep Deprivation: Effects on
Mood
 Increased dysphoria/depression
anger/hostility; decreased motivation
 Correlation with sleep amounts
 Effects last up to 48 hrs post-call
 Independent association with night shift
Sleep Deprivation –
Socioeconomic Consequences…
More than 1,000,000 motor vehicle accidents
annually are sleep-related
Disasters such as Chernobyl, Three Mile Island,
Challenger, Bhopal, and Exxon Valdez were
officially attributed to errors in judgment induced
by sleepiness or fatigue
Three Mile Island
and Chernobyl Disasters
1. US Nuclear Regulatory Commission. Report on the Accident at
Chernobyl Nuclear Power Station. Washington DC: US Government
Printing Office; 1987. 2. Moss TH, Sills DL. The Three Mile Island
nuclear accident: lessons and implications. Ann NY Acad Sci 1981;
365:1-341
Early morning
human error
Fatigue-related
accidents
Deserted city of Prypiyat with Chernobyl
nuclear reactor in the background
Exxon Valdez Grounding
NTSB. Marine Accident Report – Grounding of the US Tankership
EXXON VALDEZ on Bligh Reef, Prince William Sound, Near Valdez,
Alaska, March 24th, 1989. Washington DC: NTSB/March-90/04
“…probable cause of
the grounding of the
Exxon Valdez was the
failure of the third
mate to properly
maneuver the vessel
because of fatigue
and excessive
workload…”
Epworth Sleepiness Scale
Johns MW. Sleep 1994; 17:703-710
0 - WOULD NEVER DOZE
1 - SLIGHT CHANCE OF DOZING
2 - MODERATE CHANCE OF DOZING
3 - HIGH CHANCE OF DOZING
Sitting reading
(Range 0 – 24)
Watching TV
Sitting inactive in public
Passenger in a car for 1 hour
Sitting and talking
Sitting quietly after lunch
In a car, while stopped for a few minutes in traffic
Epworth Sleepiness Scale Scores (0-24 range)
Papp KK, et al. Acad Med 2004; 79:394-402 :
Sleepiness in residents is equivalent to that found in patients
with serious sleep disorders (normal < 10)
20
Narcolepsy
Residents
15
Sleep Apnea
10
Norm al
5
Insomnia
0
Mean
Normal
Insomnia
Sleep
Apnea
Residents
Narcoleps
y
5.90
2.20
11.70
14.70
17.50
Stanford Sleepiness Scale
An introspective measure of sleepiness – The Stanford
Sleepiness Scale (SSS)
Degree of sleepiness
Scale
Rating
Feeling active, vital, alert, or wide awake
1
Functioning at high levels, but not at peak; able to
concentrate
2
Awake, but relaxed; responsive but not fully alert
3
Somewhat foggy, let down
4
Foggy, losing interest in remaining awake, slowed down
5
Sleepy, woozy, fighting sleep, prefer to lie down
6
No longer fighting sleep, sleep onset soon, having dreamlike thoughts
7
Asleep
X
Despite this, the problem of
sleepiness and fatigue in
residency is under-estimated.
MYTH:
“It’s the really boring noon
conferences that put me to sleep.”
FACT:
Environmental factors (passive
learning situations, room
temperature, low light levels, etc.)
may unmask, but DO NOT CAUSE
SLEEPINESS!
Conceptual Framework
(in Residency)
Insufficient Sleep
(on call sleep loss/
inadequate recovery
sleep)
Fragmented Sleep
(pager, phone calls)
Excessive Daytime Sleepiness
Circadian Rhythm
Disruption
(night float, rotating shifts)
Primary
Sleep Disorders
(sleep apnea, etc)
Sleep Needed
vs Sleep Obtained
Myth: “I’m one of those people who only needs 5
hours of sleep, so none of this applies to me.”
Fact: Individuals may vary somewhat in their
tolerance to the effects of sleep loss, but are not
able to accurately judge this themselves.
Fact: Human beings need 8 hours of sleep to
perform at an optimal level.
Fact: Getting less than 8 hours of sleep starts to
create a “sleep debt” which must be paid off.
Sleep Fragmentation Affects Sleep Quality
NORMAL SLEEP
= Paged
MORNING ROUNDS
ON CALL SLEEP
The Circadian Clock Impacts You
It is easier to stay up later than
to try to fall asleep earlier.
It is easier to adapt to shifts in
forward (clockwise) direction.
(day
evening
night)
Night owls may find it easier
to adapt to night shifts.
Interaction of Circadian
Rhythms and Sleep
Sleep
Homeostatic drive
(Sleep Load)
Wake
Sleep
Alertness level
Circadian alerting signal
9 AM
3 pm
9 PM
Time
3 AM
9 AM
Sleep Disorders:
Are you at Risk?
Physicians can have sleep disorders too!
– Obstructive sleep apnea
– Restless legs syndrome
– Periodic limb movement disorder
– Learned or “conditioned” insomnia
– Medication-induced insomnia
Adaptation to Sleep Loss
Myth: “I’ve learned not to need as much
sleep during my residency.”
Fact: Sleep needs are genetically
determined and cannot be changed.
Fact: Human beings do not “adapt” to
getting less sleep than they need.
Fact: Although performance of tasks may
improve somewhat with effort, optimal
performance and consistency of
performance do not!
Consequences of Chronic Sleep
Deprivation
Sleep is a vital and necessary function,
and sleep needs (like hunger and thirst)
must be met
Workplace
Mood
And
Performance
Learning
Driving
Safety
Sleep Deprived
Resident
Patient Care
Professionalism
Health
&
Well-Being
Family
Relationships
Impairment
Across Specialties
Surgery: 20% more errors and 14% more time
required to perform simulated laparoscopy post-call
(two studies) Taffinder NJ et al, Lancet 1998; 352:1191;
Grantcharov TP et al. BMJ 2001; 323:1222
Internal Medicine: efficiency and accuracy of
ECG interpretation impaired in sleep-deprived
interns Lingenfelser T et al. Med Education 1994;28:566
Pediatrics: time required to place an intra-arterial
line increased significantly in sleep-deprived
residents Storer JS et al, Acad Med 1989; 64:291989
Surgery Residents:
Laparoscopic Skills Suffer on the First
Night Shift
Leff DR et al. Ann Surg 2008;247:530
21 residents trained on a virtual reality
surgical simulator:
Technical skills assessed on 2 tasks
Took longer (p=.002) and made more errors (p=.025) on
their first night shift
Were less economical with movements on the first night
shift
Some improvement noted during subsequent shifts
Lesson: Prepare for night shift, realize your
limitations
Across Tasks
Emergency Medicine: significant
reductions in comprehensiveness of
history & physical exam documentation in
second-year residents Bertram DA. NY State J Med
1998; 88:10-15
Family Medicine: scores achieved on the
ABFM practice in-training exam negatively
correlated with pre-test sleep amounts
Jacques CJ et al. J Fam Pract 1990; 30:223-229
Impact on Professionalism
“Your own patients have become the
enemy…because they are the one thing
that stands between you and a few
hours of sleep.”
Work Hours, Medical Errors, and
Workplace Conflicts by Average
Daily Hours of Sleep*
100
90
80
70
60
50
40
30
20
10
0
Work Hrs/wk
% Reporting Med
Errors
% Reporting Staff
Conflicts
< 4 hrs
5-6 hrs
Hours of
> 7 hrs
* Baldwin DJr et al. Acad Med
Sleep
2003;78:1154
Limiting Resident Work Hours:
Impact on Patient Safety
Fletcher KE, et al. Ann Intern Med 2004:141
Insufficient evidence
7 studies had an intervention to reduce
work hours and assessed patient safety
outcomes (4 retrospective, 3 prospective
studies)
Limitations on study design, diversity of
interventions and possibly publication bias
Do ACGME Duty Hour Rules
Impact Hospital Mortality? No?
Volpp KG et al. JAMA 2007;298:975
Compared mortality rates for all Medicare pt
admissions to teaching hospitals from 20002003 (pre duty hours reform) to 2003-2005 (after
duty hour reform)
ACGME duty hours reform was not associated
with either worsening or improvement in
mortality during the first 2 years after
implementation
Do ACGME Duty Hour Rules
Impact Hospital Mortality? Yes?
Volpp KG et al. JAMA 2007; 298:984
Compared mortality rates for all VA
Hospitals from 2000-2003 and 2003-2005
Duty hour rules were associated with
improvement in mortality for 4 common
medical conditions (AMI, CVA, GI bleed,
CHF)—but not for surgical conditions
Serious Medical Errors in the ICU
Landrigan CP et al. N Engl J Med 2004; 351:1838
Prospective randomized trial of interns
Traditional schedule with an extended (> 24 hr)
work shift every 3rd night (3 interns)
– 77 to 81 hrs/wk up to 34 hrs of continous work
Interventional schedule where one intern worked
7 am to 10 pm on call and another worked 9 pm
to 1 pm (4 interns)
– 60 to 63 hrs/wk with up to 16 continous working hours
Examined incidence of serious medical errors
Serious Medical Errors in the ICU
Landrigan CP et al. N Engl J Med 2004; 351:1838
Interns on the traditional schedule
– Made 36% more serious medical errors
– Made 21% more serious medication errors
– Made 5.6 times as many serious diagnostic
errors
Eliminating extended work shift and
reducing the number of work hours per
week can reduce serious medication
errors in the ICU
Bottom Line:
You need to be alert
to take the best possible care
of your patients...
…and yourself!
Adverse Health Consequences
by Average Daily Hours of Sleep*
Baldwin DC Jr, et al. Acad Med 2003; 78:1154
60
50
% Reporting Signif
Wgt Change
40
% Reporting Med Use
to Stay Awake
30
20
% Reporting
Increased Alcohol
Use
10
0
<4 hrs
5-6hrs
Hours of Sleep
>7 hrs
Sleep Loss and Fatigue:
Safety Issues
58% of emergency medicine residents reported
near-crashes
– 80% post night-shift
– Increased with number night shifts/month
Steele MT et al, Acad Emerg Med 1999; 6:1050
50% greater risk of blood-borne pathogen
exposure incidents (needlestick, laceration, etc) in
residents between 10 pm and 6 am
Parks DK et al, Chronobiology Intl 2000; 17:61
MICU Resident Sleepiness Post Call
Reddy R et al. Chest 2009; 135:81
20 residents on call every 4th night, home after
call at/or before noon:
Monitored sleep times with diaries and actigraphs
Stanford Sleepiness Scale (SSS) and MSLT performed
day of and day after call (2 nap sessions)
Sleep time prior to call day: 7.15 ± 1 hr
Sleep time on call: 2.5 ± 1.4 hr
On Call
SSS 1.5 ± 0.6
MSLT 9 ± 4.4 min
Post Call
3.15 ± 1
4.8 ± 4.1 min
MICU Resident Sleepiness
Post Call
Severity of sleepiness post-call
approximates someone with narcolepsy
Residents are often sleepy during on-call
and post-call days even while
implementing the ACGME guidelines
Implications for patient and resident safety
The High Price of Sleep
Deprivation…
Courtesy of Advance for Managers of Respiratory Care, Apr 2000
Sleep Loss and Fatigue:
Driving
Marcus CL et al. Sleep 1996; 19:763
Retrospective survey of 85 pediatric
residents and 85 faculty:
2.7 hrs avg sleep on-call; 7.2 hrs avg off-call
23% had fallen asleep while driving (vs 8%)
44% had fallen asleep at traffic light (vs 12.5%)
Total 49% had fallen asleep at the wheel; 90%
of incidents post-call
25 traffic citations (vs 15), 20 MVAs (vs 11)
Risk of MVA Crashes
Among Interns
Barger LK et al. N Engl J Med 2005; 352:125
Web-based survey of 2737 interns examining work hrs,
shifts, crashes, and near miss incidents (July 2002 - May
2003)
Extended work shift increased the monthly risk of an
MVA by 9.1%, and the risk during the commute from
work by 16.2%
In months where interns had > 5 extended shifts, the risk
of falling asleep while driving increased (OR 2.39) as did
the risk for falling asleep in traffic (OR 3.69)
Extended work hour shifts pose a driving safety hazard.
Sleep Deprivation & Equivalent
ETOH Levels
Wakefulness
Equivalent ETOH Level
17 hours . . . . . . . . . . .
0.05%
21 hours . . . . . . . . . . .
0.08%
24 hours . . . . . . . . . . .
0.1%
 Legally drunk level = 0.08% ETOH
 US Legal limit ETOH level for commercial drivers =
0.04%
 Maggie’s Law (New Jersey) – a sleep-deprived driver
(no sleep > 24 hrs) can be convicted of vehicular
homicide
 In almost all states, people can be charged under
existing laws if they fall asleep at the wheel
ACGME Duty Hour Limits:
Effects on Safety, Sleep and Work Hours
Landrigan CP et al. Pediatrics 2008; 122:250
220 residents, prospective cohort study,
evaluated the spring before and the spring after
implementation of ACGME duty hour standards
No change in total work or sleep hours,
medication errors, MVAs, occupational
exposures, or depression
Mean length of on call shifts decreased 2.7% to
28.5 hours (p = .001)
Resident burnout decreased from 75.4% to
57.0% (p = .007)
Outcomes Before and After
ACGME Duty Hour Standards
Landrigan CP et al. Pediatrics 2008;122:250-258
Impact on Medical Education
“We all know that you stop learning after
12 or 13 or 14 hours. You don’t learn
anything except how to cut corners and
how to survive.”
Recognizing Sleepiness in
Yourself and Others
Myth: “If I can just get through the night
(on call), I’m fine in the morning.”
Fact: A decline in performance starts after
about 15-16 hours of continued
wakefulness.
Fact: The period of lowest alertness after
being up all night is between 6 am and
11am (morning rounds).
Estimating Sleepiness
Myth: “I can tell how tired I am and I know
when I’m not functioning up to par.”
Fact: Studies show that sleepy people
underestimate their level of sleepiness
and overestimate their alertness.
Fact: The sleepier you are, the less
accurate your perception of degree of
impairment.
Fact: You can fall asleep briefly
(“microsleeps”) without knowing it!
Perceived Impact of Sleep
Deprivation
Surgical vs Non-Surgical Residents
Woodrow SI et al. Medical Education 2008; 42:459
Surgical Non-Surgical
P
Work hrs per week
83
62.5
< .01
Epworth Sleepiness Scale
12.8
9.2
< .01
Sleep Deprivation Impact Score
45.2
51.5
< .01
Surgery residents are less likely to
perceive the potential impact of sleep
deprivation on their own performance
Could it be due to optimism bias?
Be aware!
Attention Failures on Different Work
Hours
Lockley SW et al. N Engl J Med 2004; 351:1829
20 interns on 2 different 3 wk ICU rotations
Traditional and intervention work hours
Continuous ambulatory polysomnography
Attentional failures identified by slowrolling eye movements into confined
wakefulness during work hours
Attentional Failure: Example
Attentional Failures on Different
Work Hours
Lockley SW et al. N Engl J Med 2004; 351:1832
On the intervention work hour shift
schedule:
– Interns worked 19.5 hrs/wk less
– Slept more
– Had less than half of the rate of attentional
failures while working during on-call nights
Mean Number of Attentional
Failures
Lockley SW et al. N Engl J Med 2004; 351:1835
Neurocognitive Effects of Sleep
Deprivation in Residents
Arnedt JT, et al. JAMA 2005; 294-1025
Prospective 2 session within-subject study
of 34 pediatric residents
Compared post-call performance to non
post-call performance with and w/out a
blood alcohol level of 0.04 – 0.05 g %
– Sustained attention
– Vigilance
– Simulated driving
Neurocognitive Effects of Sleep
Deprivation in Residents
Arnedt JT, et al. JAMA 2005; 294:1-1025
Light call rotation – 4th week of 44 hr
work week
– Testing before and after alcohol ingestion
Heavy call rotation – 4th week of 80 hr
work week
– Testing before and after placebo ingestion
Neurocognitive Effects of Sleep
Deprivation in Residents
Arnedt JT, et al. JAMA 2005; 294:1-1025
Heavy call:
– Reaction times 7% slower
– Commission errors 40% higher
– Simulated driving lane variability 27% greater
– Simulated driving speed variability 71%
greater
– Results similar to light call results with a 0.04
to 0.05 g % blood alcohol level
Residents could not judge this impairment
Neurocognitive Effects of Sleep
Deprivation in Residents
Arnedt JT, et al. JAMA 2005; 294:1-1025
Post-call performance impairment is present
Impairment is comparable to drinking 3 to 4
alcoholic drinks
Residents have limited ability to recognize their
degree of impairment
Potential risk to personal and patient safety
Consider interventions to minimize impact
Recognize The
Warning Signs of Sleepiness
Falling asleep in conferences or on rounds
Feeling restless and irritable with staff,
colleagues, family, and friends
Having to check your work repeatedly
Having difficulty focusing on the care of
your patients
Feeling like you really just don’t care
Be Aware of Sleep Inertia
Clouded sensorium when arousing from sleep
Confusion, slowed speech, repeating phrases or
questions
Vulnerable time: answering a beeper or phone
call when asleep
Can’t retain information
We may not recognize our own sleep inertia
Reversible with < 10 minutes of stimulation like
movement and caffeine
Manage it before making important medical
decision
If you don’t recognize that
you’re sleepy,
you’re not likely to do
anything about it.
Alertness Management
Strategies
Myth: “I’d rather just “power through”
when I’m tired; besides, even when I
can nap, it just makes me feel worse.”
Fact: Some sleep is always better than
no sleep.
Fact: At what time and for how long you
sleep are key to getting the most out of
napping.
Napping
Pros: naps temporarily improve
alertness
Types:
– Preventative (pre-call)
– Operational (on the job)
Length:
– Short naps: no longer than 30 minutes to avoid
the grogginess (“sleep inertia”) that occurs when
you’re awakened from deep sleep
– Long naps: 2 hours (range 30 to 180 minutes)
Napping
Timing:
– if possible, take advantage of circadian
“windows of opportunity” (2 to 5 am/2 to
5 pm)
– but if not, nap whenever you can!
Cons: sleep inertia; allow adequate
recovery time (15-30 minutes)
Bottom line: naps take the edge off but do
not replace adequate sleep.
Healthy Sleep Habits
Get adequate (7 to 9 hours) sleep before
anticipated sleep loss.
Avoid starting out with
a sleep deficit!
Recovery from Sleep Loss
Myth: “All I need is my usual 5 to 6
hours the night after call and I’m fine.”
Fact: Recovery from on-call sleep loss
generally takes 2 nights of extended
sleep to restore baseline alertness.
Fact: Recovery sleep generally has a
higher percentage of deep sleep, which
is needed to counteract the effects of
sleep loss.
Healthy Sleep
Habits
Go to bed and get up at about
the same time every day
Develop a pre-sleep routine
Use relaxation to help you fall asleep
Protect your sleep time; enlist your
family and friends!
Healthy Sleep Habits
Sleeping environment:
– No animals!
– Cooler temperature
– Dark (eye shades, room darkening shades)
– Quiet (unplug phone, turn off pager, use
ear plugs, white noise machine)
Avoid going to bed hungry, but no heavy
meals within 3 hours of sleep.
Get regular exercise but avoid heavy exercise
within 3 hours of sleep.
Recognize Signs of DWD*
Trouble focusing on the road
Difficulty keeping your eyes open
Nodding
Yawning repeatedly
Drifting from your lane, missing signs or
exits
Not remembering driving the last few miles
Closing your eyes at stoplights
* Driving While Drowsy
Risk Factors for Drowsy Driving
Pack A et al. Anal Prev 1995; 27:769
Taking any sedating medications
Drinking even small amounts of alcohol
Having a sleep disorder (sleep apnea)
Driving long distances without breaks
Driving alone or on a boring road
450
400
350
300
250
200
150
100
50
0
of
Number
Number of
Crashes
Crashes
•
•
•
•
•
Time of Day
0:00
3:00
6:00
9:00
12:00
Time of Day
15:00
18:00
21:00
Driving home post-call
Drowsy Driving:
What DOES NOT Work
Turning up the radio
Opening the car window
Chewing gum
Blowing cold air (water) on your face
Slapping (pinching) yourself hard
Promising yourself a reward for staying
awake
It takes only a 4 second lapse
in attention to have a drowsy
driving crash.
Post-call MVA Driving Home
Who’s Liable?
American Medical News, October 31, 2005
In July 1997, an intern at Rush University Medical Center
had an MVA while driving home after being on call for 36
hours
A 23 year-old woman sustained a head injury which has
left her totally disabled
Her family is suing the intern and the teaching hospital
because the hospital enforced a work schedule resulting
in sleep deprivation
Hospital not responsible
Under appeal/no further action as of February 2009
Drugs
AVOID using stimulants (methylphenidate,
dextroamphetamine) to stay awake
AVOID using alcohol to help you fall asleep; it
induces sleep onset but disrupts sleep later on.
Modafinil: little data
Melatonin: little data in residents
Hypnotics: may be helpful in specific situations (eg,
persistent insomnia)
Caffeine
Strategic consumption is key
Effects within 15 – 30 minutes;
half-life 3 to 7 hours
Use for temporary relief of sleepiness
Cons:
– disrupts subsequent sleep (more arousals)
– tolerance may develop
– diuretic effects
Adapting to Night Shifts
Myth: “I get used to night shifts right
away; no problem.”
Fact: It takes at least a week for circadian
rhythms and sleep patterns to adjust.
Fact: Adjustment often includes physical
and mental symptoms (think jet lag).
Fact: Direction of shift rotation affects
adaptation (forward/clockwise easier to
adapt).
How to Survive Night Float
Protect your sleep
Nap before work
Consider “splitting” sleep into two 4 hour
periods
Have as much exposure to bright light as
possible when you need to be alert
Avoid light exposure in the
morning after night shift
(wear dark glasses
driving home from work)
Alertness Strategies
There is no “magic bullet”
Know your own vulnerability to
sleep loss
Learn what works for you from a
range of strategies
There needs to be a shared
responsibility for fatigue management
and a “culture of support” in the
training program
Effects of Work Hour Reduction on
Residents’ Lives
Fletcher KE, et al. JAMA 2005; 294:1088
12 studies -- performed on Internal
Medicine residents
Nurse perceptions -- residents made fewer
mistakes and they were easier to work
with
Faculty perceptions -- residents learned
less and developed a shift-work mentality
Program Directors perceptions -- 81%
agreed that resident morale improved
when night float system used
Effects of Work Hour Reduction on
Residents’ Lives
Fletcher KE, et al. JAMA 2005; 294:1088
Resident perceptions:
– Decreased work hours
– Increased sleep time
– Fewer attention failures
– More time with family
– Less impact of fatigue on learning
– No difference in mood
Resident Attitudes About ACGME
Duty Hour Regulations
Myers JS et al. Acad Med 2006; 81:1052
Surveyed 200 residents trained both before and
after implementation at 6 residency pgms (3 IM,
3 GS) 2 yrs after implementation
Fatigue-related errors decreased slightly
Errors related to continuity of care significantly
increased
Opportunities for formal education, bedside
learning and procedures decreased
Quality of life improved and burnout decreased
In Summary...
Fatigue is an impairment—like alcohol or drugs
Drowsiness, sleepiness, and fatigue cannot be
eliminated in residency, but can be managed
Recognition of sleepiness and fatigue and use of
alertness management strategies are simple
ways to help combat sleepiness in residency
When sleepiness interferes with your
performance or health, talk to your supervisors
and program director
International Medical News, Sep 1, 2005
Sleepy Driving
From Sleep Review, Mar-Apr 2005, pg 38
Sleepy Driver Crash Video
Computer must be connected to the internet.
Open your browser: Go to the YouTube
website: (www.youtube.com)
Search for: “Sleepy Driver Crash” video clip,
or click http://www.youtube.com/watch?v=sjkbhO8I2I
then minimize it. When you are ready to
view the video, double-click on the URL at the
bottom of the screen.