Mitigating the Impact of Pandemic (H1N1): Options for Public Health Measures Dr Li Ailan Communicable Disease Surveillance & Response (CSR) WHO Western Pacific Regional.
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Mitigating the Impact of Pandemic (H1N1): Options for Public Health Measures Dr Li Ailan Communicable Disease Surveillance & Response (CSR) WHO Western Pacific Regional Office (WPRO) 3rd Meeting of the National Influenza Centres in the Western Pacific and South-East Asia Regions 18-20 August 2009, Beijing, China Outline What options are available for public health interventions? What have countries prepared for non-pharmaceutical interventions? What actual public health measures have been applied or being implemented in response to pandemic (H1N1) 2009? Conclusion Communicable Disease Surveillance and Response (CSR) WHO Western Pacific Regional Office (WPRO) Primary Strategies for Combating Influenza Pharmaceutical interventions – Use of matched vaccines – Use of effective antiviral drugs Non-pharmaceutical interventions – Individual and household level public health measures – Societal level public health measures, including social distancing Communicable Disease Surveillance and Response (CSR) WHO Western Pacific Regional Office (WPRO) Goals of Public Health Intervention Delay outbreak peak 1 Delay spread and shift an epidemic curve to the right side – to reduce peak burden on health care facilities (e.g. hospitals) – to “buy time” for other measures (e.g. vaccination) Reduce morbidity and mortality through reducing the total number of cases Communicable Disease Surveillance and Response (CSR) WHO Western Pacific Regional Office (WPRO) 2 3 Public Health Measures Available (theoretically) at national and community level 1. Individual/household measures Personal protective measures Isolation & quarantine Infection prevention and control in the home setting Use of masks in the community setting 2. Societal measures, including social distancing Suspension of classes and child care programmes Adjusting or changing work patterns Restriction of public or mass gatherings Domestic travel advisories and restrictions Communicable Disease Surveillance and Response (CSR) WHO Western Pacific Regional Office (WPRO) Public Health Measures Available (theoretically) at the international border 1. International travel and screening Health advice and alerts to travellers Health declaration form Temperature screening On-board identification of suspected travellers International travel advisory, restriction, border closure? 2. Management of symptomatic & exposed travellers Symptomatic travellers (isolation & treatment…) Exposed travellers (quarantine…) Communicable Disease Surveillance and Response (CSR) WHO Western Pacific Regional Office (WPRO) Key considerations Decision on public health measures based on risk assessment, especially severity and potential impact Public health measures should be evidence-based whenever possible Countries should balance the benefits against the costs and potential consequences Need to be tailored to suit country or local context Planning, coordination and communication is essential Communicable Disease Surveillance and Response (CSR) WHO Western Pacific Regional Office (WPRO) Comparative risk of outbreaks Transmissibility Low Severity of High Disease High H5N1 SARS (Morbidity & Mortality) 1918 Pandemic Pandemic (H1N1) 2009? Low Communicable Disease Surveillance and Response (CSR) WHO Western Pacific Regional Office (WPRO) Seasonal Flu Possible strategies based on risk category Transmissibility Low Severity of High Disease Aiming at preventing disease importation and containing the virus Aiming at rapid containment at the early stage, and mitigating the impacts, if containment not possible Routine public health measures without additional aggressive interventions Aiming at reducing transmission and mitigating impact with focus on vulnerable population (Morbidity & Mortality) Low High Communicable Disease Surveillance and Response (CSR) WHO Western Pacific Regional Office (WPRO) Matching cost and consequences of interventions with risk level More acceptable interventions 1918 pandemic virus or worse C A D B E Level of Risk SARS New H1N1 ??? Seasonal Influenza F Less acceptable interventions E.g. Respiratory hygiene E.g. Isolation & quarantine Cost s and Consequences Communicable Disease Surveillance and Response (CSR) WHO Western Pacific Regional Office (WPRO) E.g. Travel restriction Options for interventions: Decision Matrix Options School closure Benefits Reducing transmission among children and decreasing spread to the community Acceptable in some countries Limitations & consequence Decision (Yes/No/wait) high social & economic cost Second consequences Need alternative childcare programme Absenteeism of working parents, including HCWs Educational continuity? Comments & guidance: -Must weight the benefits of reducing transmission against economic and social costs -Decision based on local situation and context (“case-by-case”)… -… Communicable Disease Surveillance and Response (CSR) WHO Western Pacific Regional Office (WPRO) Pandemic Preparedness Assessment 2009 Annual assessment of pandemic preparedness was conducted in May-June, using the WHO WPRO and CDC Joint Assessment Tool A supplementary questionnaire on public health measures was added in this “readiness” survey – Is this public health measure included in your national response plan? – Did you apply or consider applying this measure? – What is your trigger to start and stop the public health intervention? The questionnaire was distributed to collect data from 17 countries and areas, 15 (88%) responded to the survey Communicable Disease Surveillance and Response (CSR) WHO Western Pacific Regional Office (WPRO) Pandemic Preparedness Assessment 2009: Public Health Measures at International Borders A. Public Health Measures at International Borders % of 'Yes' Response from Member States 100% 90% 80% 70% 60% 50% 40% 30% 20% 10% 0% Health alerts f or travellers Health declaration f orm/card Passenger screening Management of symptomatic travellers Public Health Measure Management of exposed travellers In Pandemic Response Plan? Conduct / consider activities? Communicable Disease Surveillance and Response (CSR) WHO Western Pacific Regional Office (WPRO) Pandemic Preparedness Assessment 2009: Individual/Household level Measures B. Individual / Household Level Public Health Measures % of 'Yes' Response from Member States 100% 90% 80% 70% 60% 50% 40% 30% 20% 10% 0% Hand and respiratory hygiene Isolation of ill people Quarantine of contacts Inf ection prevention & Use of masks in control f or home community settings caregivers In Pandemic Response Plan? Public Health Measure Communicable Disease Surveillance and Response (CSR) WHO Western Pacific Regional Office (WPRO) Conduct / consider activities? Pandemic Preparedness Assessment 2009: Societal level Measures C. Societal Level Public Health Measures % of 'Yes' Response from Member States 100% 90% 80% 70% 60% 50% 40% 30% 20% 10% 0% Closure of school and childcare f acilities Restriction/cancellation of public or mass gatherings Adjusting or changing w ork patterns Public He alth M e asure Domestic travel advisories, restrictions, other measures In Pandemic Response Plan? Conduct / consider activities? Communicable Disease Surveillance and Response (CSR) WHO Western Pacific Regional Office (WPRO) Responding to Pandemic (H1N1) 2009 Based on risk assessment, most countries with community transmission have shifted from “containment” efforts to “mitigation” strategies Robust risk assessment help ensure appropriate public health measures are planned and implemented. Public health interventions have been dynamic in the region with most countries and areas implemented – relatively “aggressive” border measures including passengers’ screening – personal hygiene behaviour interventions – school closures at the early stage of outbreaks Communicable Disease Surveillance and Response (CSR) WHO Western Pacific Regional Office (WPRO) Example: School closure At the early stage of Pandemic (H1N1) 2009, the large proportion of school children and young adults affected School closure measure has been most frequently used as compared with other social level measures Many countries used school closure measures in the Asia Pacific Region, including Australia, China, Japan, Malaysia, New Zealand, the Philippines, Singapore and Thailand… Types of measures varied: from “real” school closure or class dismissal, from “proactive” or “reactive” approach… Length of closure varied: mostly 7-14 days Communicable Disease Surveillance and Response (CSR) WHO Western Pacific Regional Office (WPRO) School closure in Japan (May 2009) 17 May: Schools closed Hyogo Prefecture 17 May : Schools closed, in Osaka 30 35 25 30 学校閉鎖 20 兵庫県(神戸市 以外) 神戸市 15 25 20 15 10 10 5 5 0 0 5/1 5/8 5/15 5/22 Source: NIID, Japan Communicable Disease Surveillance and Response (CSR) WHO Western Pacific Regional Office (WPRO) 府内その他 :44例 A中学高等学校 :87例 School closure in Japan (June 2009) Schools and Kindergartens in Fukuoka were closed on 7 June 18 16 14 12 その他 10 渡航歴あり Source: NIID, Japan Communicable Disease Surveillance and Response (CSR) WHO Western Pacific Regional Office (WPRO) 06月30日 06月28日 06月26日 06月24日 06月22日 06月20日 06月18日 06月16日 06月14日 06月12日 06月10日 06月08日 06月06日 板小 06月04日 0 06月02日 板中 05月31日 2 05月29日 その他小学校 05月27日 4 05月25日 宮竹幼稚園 05月23日 6 05月21日 幼児 05月19日 8 Conclusion The potential benefits of public health measures should be carefully balanced against their potentially significant social and economic costs Decision based on assessed situation and local context. No standard, single combination of measures will fit all countries – “one size will not fit all” Available information indicated some public health measures have helped slow down the spread of the virus Need for continuing planning, monitoring and evidence Communicable Disease Surveillance and Response (CSR) WHO Western Pacific Regional Office (WPRO) Interim guidance available Mitigating the impact of pandemic (H1N1) 2009: Options for public health measures Responding to pandemic (H1N1) 2009: Options for interventions at international points of entry http://www.wpro.who.int/health_topics/h1n1/tech/tec h_guidance.htm Communicable Disease Surveillance and Response (CSR) WHO Western Pacific Regional Office (WPRO) Acknowledgement Dr Takeshi Kasai, Regional Advisor, CSR/WPRO Dr Nobuhiko Okabe, NIID, Japan Ms Qiu Yi Khut, CSR/WPRO Ms Katie Harrigan, CSR/WPRO Communicable Disease Surveillance and Response (CSR) WHO Western Pacific Regional Office (WPRO)