Transcript ESFRI European Strategy Forum on Research Infrastructures ESFRI Roadmap of Research Infrastructures and the Israeli Perspective David Horn, Tel Aviv University http://horn.tau.ac.il July, 2009

ESFRI
European Strategy Forum
on Research Infrastructures
ESFRI Roadmap of Research
Infrastructures
and the Israeli Perspective
David Horn, Tel Aviv University
http://horn.tau.ac.il
July, 2009
ESFRI
European Strategy Forum
on Research Infrastructures
General information
• ESFRI, the European Strategy Forum on Research Infrastructures,
is a strategic instrument to develop the scientific integration of
Europe and to strengthen its international outreach.
• Founded in 2002. Members nominated by Member and Associate
countries.
• The mission of ESFRI is to support a coherent and strategy-led
approach to policy-making on research infrastructures in Europe,
and to facilitate multilateral initiatives leading to the better use and
development of research infrastructures, at EU and international
level.
• Publication of first roadmap in 2006, and second roadmap in 2008.
• Roadmaps are used by DG research as basis of appropriate calls
for RI projects.
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ESFRI
European Strategy Forum
on Research Infrastructures
Roadmap structure
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Social Sciences and Humanities
Environmental Sciences
Energy
Biological and Medical Sciences
Materials and Analytical Facilities
Physical Sciences and Engineering
e-Infrastructures
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ESFRI
European Strategy Forum
on Research Infrastructures
Social Sciences and
Humanities
• European Social Survey
Upgrade of the European Social Survey, set up in 2001 to monitor
longterm changes in social values
Costs: construction 54M, operation 9M.
(Noah Levin-Epstein, TAU)
• SHARE
Data infrastructure for empiric economic and social science analysis
of ongoing changes due to population ageing
Costs: 11.6M, 0.3M.
(Howie Litwin, HU)
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European Strategy Forum
on Research Infrastructures
Biological and Medical
Sciences
• BBMRI
Bio-banking and biomolecular resources research infrastructure
Costs: 170M, 15M.
(INTB, Ciechanover et al ?)
• INSTRUCT
Integrated Structural Biology Infrastructure
Costs: 300M, 25M.
(Joel Sussman, WIS)
• ELIXIR
Upgrade of the European Life-science infrastructure for
biological information
Costs:470M, 100M.
(Michal Linial, HUJ, MoS)
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ESFRI
European Strategy Forum
on Research Infrastructures
BBMRI: Biobanking and Biomolecular
Resources Research Infrastructure
EC: 5 M€
27 months 50 participants
BBMRI will comprise
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all major population-based and disease-oriented biobank formats
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Biomolecular resources, such as collections of antibodies and other affinity binders
and a variety of molecular tools to decipher protein interactions and function
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bio-computing and sample storage infrastructure.
BBMRI will provide:
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Biobanks of different formats (based on collections of DNA, tissue, cells, blood and
other body fluids, together with pertinent medical, environmental, life-style and
follow-up data)
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Population cohorts, including prospective and twin cohorts
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Clinical case/control cohorts including disease-focused cohorts
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Cohorts from isolated populations
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Biomolecular resources (comprising antibody and affinity binder collections, ORF
clone collections, siRNA libraries, proteins, cellular resources etc.)
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Enabling technologies and high-throughput analysis platforms and integration of
sites specialized in development of molecular tools to decipher gene, protein and
metabolite functions and their interactions
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Harmonized standards for sample collection, storage, preanalytics and analysis
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Harmonized data collection, logistics and database- and biocomputing infrastructure
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Ethical, legal and societal guidance and platform.
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ESFRI
European Strategy Forum
on Research Infrastructures
INSTRUCT: Integrated Structural Biology
EC: 4.5 M€ 24 months 13 partners
The seven core centers comprising INSTRUCT are:
• Core A: University of Oxford, UK (Prof. Dave Stuart, Coordinator for
INSTRUCT) - multi-disciplinary approaches.
• Core B: CIRMMP Florence, Italy (Prof. Ivano Bertini) - NMR-based
and integrated biophysical investigation of the structure and dynamics
of biomolecules.
• Core C: IGBMC Strasbourg, France (Prof. Dino Moras) - multi-scale
structural biology of proteins, nucleic acids and their complexes.
• Core D: The Weizmann Institute, Israel (Prof. Joel L. Sussman) multidisciplinary resource (X-ray/NMR/EM) for elucidation of structure
and dynamics.
• Core E: EMBL (Dr. Stephen Cusack) - provide integrated structural
biology infrastructures, including synchrotron X-ray and imaging
technologies.
• Core F: MPI Munich, Germany (Prof. Wolfgang Baumeister) - broad
expertise in high-resolution 3D imaging, with unique strength in using
cryo-electron tomography.
• Core G: MPI Frankfurt, Germany (Prof. Hartmut Michel) - integrated
biophysical and structural analyses of macromolecular complexes,
including membrane proteins.
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ESFRI
European Strategy Forum
on Research Infrastructures
ELIXIR: Upgrade of European
Bioinformatics Infrastructure
EC: 4.5 M€
38 months
32 partners
www.elixir-europe.org
ELIXIR will permit the integration and interoperability
of diverse, heterogeneous, potentially redundant information that is essential to
generate and utilize biological knowledge. It will encompass the necessary
major computer infrastructure to store and organize this data in a way suitable
for rapid search and access, and will provide a sophisticated and user-friendly
portal for users.
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ESFRI
European Strategy Forum
on Research Infrastructures
Other
• ESRF Upgrade (Analytical Facilities)
Upgrade of the European Synchrotron Radiation Facility
Costs: 238M, 83M
• EPOS (Environmental Sciences)
Infrastructure for the study of tectonics and Earth surface dynamics
Costs: 500M, 80M
• LIFEWATCH (Environmental Sciences)
Infrastructure for research on the protection, management and
sustainable use of biodiversity
Costs: 370M, 71M
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Swedish research infrastructures
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European Strategy Forum
on Research Infrastructures
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Swedish research infrastructures - continued
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European Strategy Forum
on Research Infrastructures
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European Strategy Forum
on Research Infrastructures
Finland’s example
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ESFRI
European Strategy Forum
on Research Infrastructures
Finland’s example
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ESFRI
European Strategy Forum
on Research Infrastructures
Relevant current IL RI funding
• ESRF, funded by TELEM since 1999. Current annual
funding (mostly by VATAT) is roughly 1M euro.
• Geant, internet infrastructure, funded by TELEM 1999-
2002. Ongoing funding by universities through IUCC (‘machba’).
• ISRAGRID, novel e-infrastruture, funded by TELEM
2009-2013. Will become part of european grid initiative.
• EMBL+EMBC, funded by MOS. Annual costs 0.9 M
euro. Relevant to ELIXIR, the proposed EBI upgrade.
• ESS, vatat funds $200K*2 years.
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ESFRI
European Strategy Forum
on Research Infrastructures
Israel’s RI Roadmap
• Israel’s strategy is being planned by VATAM, the Israel
Committee for National Research Infrastructures
• VATAM was established by MOLMOP, the Israel National
Council for Research and Development
• VATAM serves as an advisory board to governmental agencies
(including TELEM) on questions regarding RIs.
• MOLMOP has called for the establishment of a national fund
dedicated to RI, aiming for annual expenditures of 100 M NIS.
• VATAM has started a national RI survey, carried out by the
Ne’eman institute of the Technion. This survey will serve as the
basis for future planning of an RI roadmap.
• See http://horn.tau.ac.il/vatam.html for further information
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