Post parturient hemoglobinuria (PPH) **it is common occur in highly producing dairy cows in the 1st 2-4 weeks after calving & in the.

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Transcript Post parturient hemoglobinuria (PPH) **it is common occur in highly producing dairy cows in the 1st 2-4 weeks after calving & in the.

Slide 1

Post parturient hemoglobinuria
(PPH)

**it is common occur in highly producing dairy cows in the
1st 2-4 weeks after calving & in the 5th – 7th month of
pregnancy in buffaloes .
**age of susceptibility → 3rd – 6th calving.
**It is caused by low phosphorus level in the blood resulting
from low phosphorus intake either by ration or grazing on
pasture for long period 3-4 months as barseem.
**The diseases mainly occur in winter as the animals
feeding mainly on barseem (Nov.- May.). Addition of
bran and bone meal to the ration are necessary during
barseem season.

Clinical signs
-Hb uria (urine color → light brown or reddish or coffee)
-anorexia , pica, severe decrease of milk yield , loss of b.wt &
.weakness
-secondary ketosis
-dehydration
-pale M.M → then jaundice with normal body temperature
-the course of disease → 3-5 days in standing position →
followed by weakness & sternal recumbancy for 3-5 days
-in chronic case → ketosis & locomotors disturbance

Treatment
1- in severe anemia → blood transfusion (4-5 liter)
2-give source of phosphorus :
a- Sod.dibasic phosphate or Sod.acid phosphate → 60 gm
/ 300 ml D.W filtred and given /I.V → followed by S/C dose
after 12 hr for 3-5days . Also , oral dose (80 gm ) / daily / till 3
days after recovery
b- give patent preparation as :
-Catozal , cafozal, phosphozal → 50 cm / I.V/ daily /
3-5 days.
-Tonophosphan → 50 cm / I.V / daily/ 3-5 days
3 -Arsinal 15 cc I/M daily / 3 days
4- fluid therapy (very very important) :
2 liter saline + 3 liter glucose 5 % / I.V

N.B: *addition of bran & bone meal to the ration during
barseem season
*if the cow recumbent before calving → give it
phosphorus therapy as APROPHYLACTIC

D.D
Red urine

hematuria

Hemoglobin uria

Myoglobin uria

Urine sample
Sedimentation (centrifugation)

*presence of sediment:
it is hematouria
microscopical exam → intact RBCs

Presence of homogenous & transparent
fluid :
It may be

Hb uria
Myoglobinuria

-If presence of homogenous & transparent fluid :
you may take serum sample & see its color :
*if it is of pink color → Hb uria
*if it is of clear color → Myoglobin uria

**Hb uria (caused by )
1- Babesia → -tick infestation
-young age more susceptible
-profuse diarrhea (pipe steam diarrhea) ,
then constipation
-M.M → congested → pale → jundice
-blood film → parasite

2-Bacillary Hb:
-sudden death (every 3 days)
-high fever
-sudden drop in milk yield
-blood stained feces
-necrosis in liver ( p.m)
- most common with liver fluke infestation
&during summer

3-Leptospira:
-calves & lambs are more susceptible than
adult
-pyrexia (41-42ºc) → abortion
-high mortality rate in calves & lambs
-bloody milk from all qurters
-the udder is soft & flappy

4-copper poisoning
-no fever

-severe jaundice

5-water intoxication
-history of ingestion of large amount of cold
water

6-hypophosphatemia
***Hematouria (caused by)
1-pyelonephritis
-fever in acute
-urine contain RBCs & pus cell
-rectally → pain , enlargement of kidney , absence of
its lobulation , cord like urter
-frequent , painful urination
-vaginal purulent discharge

2-Cystitis
-rectally is → thickening in wall of U.B &
painful in acute
-urine → has RBCs & pus cell
-frequent , painful urination

3-Urolithiasis
-in castrated male ruminant (fattening)
-retention of urine (auria)
-few drop of blood stained urine
-rectally → distention of U.B

4-Enzootic hematouria (neoplasm in U.B)
-affect old age only
-persistent red urine for long period of time
-presence of blood clots in urine

Thank you
and
Good luck


Slide 2

Post parturient hemoglobinuria
(PPH)

**it is common occur in highly producing dairy cows in the
1st 2-4 weeks after calving & in the 5th – 7th month of
pregnancy in buffaloes .
**age of susceptibility → 3rd – 6th calving.
**It is caused by low phosphorus level in the blood resulting
from low phosphorus intake either by ration or grazing on
pasture for long period 3-4 months as barseem.
**The diseases mainly occur in winter as the animals
feeding mainly on barseem (Nov.- May.). Addition of
bran and bone meal to the ration are necessary during
barseem season.

Clinical signs
-Hb uria (urine color → light brown or reddish or coffee)
-anorexia , pica, severe decrease of milk yield , loss of b.wt &
.weakness
-secondary ketosis
-dehydration
-pale M.M → then jaundice with normal body temperature
-the course of disease → 3-5 days in standing position →
followed by weakness & sternal recumbancy for 3-5 days
-in chronic case → ketosis & locomotors disturbance

Treatment
1- in severe anemia → blood transfusion (4-5 liter)
2-give source of phosphorus :
a- Sod.dibasic phosphate or Sod.acid phosphate → 60 gm
/ 300 ml D.W filtred and given /I.V → followed by S/C dose
after 12 hr for 3-5days . Also , oral dose (80 gm ) / daily / till 3
days after recovery
b- give patent preparation as :
-Catozal , cafozal, phosphozal → 50 cm / I.V/ daily /
3-5 days.
-Tonophosphan → 50 cm / I.V / daily/ 3-5 days
3 -Arsinal 15 cc I/M daily / 3 days
4- fluid therapy (very very important) :
2 liter saline + 3 liter glucose 5 % / I.V

N.B: *addition of bran & bone meal to the ration during
barseem season
*if the cow recumbent before calving → give it
phosphorus therapy as APROPHYLACTIC

D.D
Red urine

hematuria

Hemoglobin uria

Myoglobin uria

Urine sample
Sedimentation (centrifugation)

*presence of sediment:
it is hematouria
microscopical exam → intact RBCs

Presence of homogenous & transparent
fluid :
It may be

Hb uria
Myoglobinuria

-If presence of homogenous & transparent fluid :
you may take serum sample & see its color :
*if it is of pink color → Hb uria
*if it is of clear color → Myoglobin uria

**Hb uria (caused by )
1- Babesia → -tick infestation
-young age more susceptible
-profuse diarrhea (pipe steam diarrhea) ,
then constipation
-M.M → congested → pale → jundice
-blood film → parasite

2-Bacillary Hb:
-sudden death (every 3 days)
-high fever
-sudden drop in milk yield
-blood stained feces
-necrosis in liver ( p.m)
- most common with liver fluke infestation
&during summer

3-Leptospira:
-calves & lambs are more susceptible than
adult
-pyrexia (41-42ºc) → abortion
-high mortality rate in calves & lambs
-bloody milk from all qurters
-the udder is soft & flappy

4-copper poisoning
-no fever

-severe jaundice

5-water intoxication
-history of ingestion of large amount of cold
water

6-hypophosphatemia
***Hematouria (caused by)
1-pyelonephritis
-fever in acute
-urine contain RBCs & pus cell
-rectally → pain , enlargement of kidney , absence of
its lobulation , cord like urter
-frequent , painful urination
-vaginal purulent discharge

2-Cystitis
-rectally is → thickening in wall of U.B &
painful in acute
-urine → has RBCs & pus cell
-frequent , painful urination

3-Urolithiasis
-in castrated male ruminant (fattening)
-retention of urine (auria)
-few drop of blood stained urine
-rectally → distention of U.B

4-Enzootic hematouria (neoplasm in U.B)
-affect old age only
-persistent red urine for long period of time
-presence of blood clots in urine

Thank you
and
Good luck


Slide 3

Post parturient hemoglobinuria
(PPH)

**it is common occur in highly producing dairy cows in the
1st 2-4 weeks after calving & in the 5th – 7th month of
pregnancy in buffaloes .
**age of susceptibility → 3rd – 6th calving.
**It is caused by low phosphorus level in the blood resulting
from low phosphorus intake either by ration or grazing on
pasture for long period 3-4 months as barseem.
**The diseases mainly occur in winter as the animals
feeding mainly on barseem (Nov.- May.). Addition of
bran and bone meal to the ration are necessary during
barseem season.

Clinical signs
-Hb uria (urine color → light brown or reddish or coffee)
-anorexia , pica, severe decrease of milk yield , loss of b.wt &
.weakness
-secondary ketosis
-dehydration
-pale M.M → then jaundice with normal body temperature
-the course of disease → 3-5 days in standing position →
followed by weakness & sternal recumbancy for 3-5 days
-in chronic case → ketosis & locomotors disturbance

Treatment
1- in severe anemia → blood transfusion (4-5 liter)
2-give source of phosphorus :
a- Sod.dibasic phosphate or Sod.acid phosphate → 60 gm
/ 300 ml D.W filtred and given /I.V → followed by S/C dose
after 12 hr for 3-5days . Also , oral dose (80 gm ) / daily / till 3
days after recovery
b- give patent preparation as :
-Catozal , cafozal, phosphozal → 50 cm / I.V/ daily /
3-5 days.
-Tonophosphan → 50 cm / I.V / daily/ 3-5 days
3 -Arsinal 15 cc I/M daily / 3 days
4- fluid therapy (very very important) :
2 liter saline + 3 liter glucose 5 % / I.V

N.B: *addition of bran & bone meal to the ration during
barseem season
*if the cow recumbent before calving → give it
phosphorus therapy as APROPHYLACTIC

D.D
Red urine

hematuria

Hemoglobin uria

Myoglobin uria

Urine sample
Sedimentation (centrifugation)

*presence of sediment:
it is hematouria
microscopical exam → intact RBCs

Presence of homogenous & transparent
fluid :
It may be

Hb uria
Myoglobinuria

-If presence of homogenous & transparent fluid :
you may take serum sample & see its color :
*if it is of pink color → Hb uria
*if it is of clear color → Myoglobin uria

**Hb uria (caused by )
1- Babesia → -tick infestation
-young age more susceptible
-profuse diarrhea (pipe steam diarrhea) ,
then constipation
-M.M → congested → pale → jundice
-blood film → parasite

2-Bacillary Hb:
-sudden death (every 3 days)
-high fever
-sudden drop in milk yield
-blood stained feces
-necrosis in liver ( p.m)
- most common with liver fluke infestation
&during summer

3-Leptospira:
-calves & lambs are more susceptible than
adult
-pyrexia (41-42ºc) → abortion
-high mortality rate in calves & lambs
-bloody milk from all qurters
-the udder is soft & flappy

4-copper poisoning
-no fever

-severe jaundice

5-water intoxication
-history of ingestion of large amount of cold
water

6-hypophosphatemia
***Hematouria (caused by)
1-pyelonephritis
-fever in acute
-urine contain RBCs & pus cell
-rectally → pain , enlargement of kidney , absence of
its lobulation , cord like urter
-frequent , painful urination
-vaginal purulent discharge

2-Cystitis
-rectally is → thickening in wall of U.B &
painful in acute
-urine → has RBCs & pus cell
-frequent , painful urination

3-Urolithiasis
-in castrated male ruminant (fattening)
-retention of urine (auria)
-few drop of blood stained urine
-rectally → distention of U.B

4-Enzootic hematouria (neoplasm in U.B)
-affect old age only
-persistent red urine for long period of time
-presence of blood clots in urine

Thank you
and
Good luck


Slide 4

Post parturient hemoglobinuria
(PPH)

**it is common occur in highly producing dairy cows in the
1st 2-4 weeks after calving & in the 5th – 7th month of
pregnancy in buffaloes .
**age of susceptibility → 3rd – 6th calving.
**It is caused by low phosphorus level in the blood resulting
from low phosphorus intake either by ration or grazing on
pasture for long period 3-4 months as barseem.
**The diseases mainly occur in winter as the animals
feeding mainly on barseem (Nov.- May.). Addition of
bran and bone meal to the ration are necessary during
barseem season.

Clinical signs
-Hb uria (urine color → light brown or reddish or coffee)
-anorexia , pica, severe decrease of milk yield , loss of b.wt &
.weakness
-secondary ketosis
-dehydration
-pale M.M → then jaundice with normal body temperature
-the course of disease → 3-5 days in standing position →
followed by weakness & sternal recumbancy for 3-5 days
-in chronic case → ketosis & locomotors disturbance

Treatment
1- in severe anemia → blood transfusion (4-5 liter)
2-give source of phosphorus :
a- Sod.dibasic phosphate or Sod.acid phosphate → 60 gm
/ 300 ml D.W filtred and given /I.V → followed by S/C dose
after 12 hr for 3-5days . Also , oral dose (80 gm ) / daily / till 3
days after recovery
b- give patent preparation as :
-Catozal , cafozal, phosphozal → 50 cm / I.V/ daily /
3-5 days.
-Tonophosphan → 50 cm / I.V / daily/ 3-5 days
3 -Arsinal 15 cc I/M daily / 3 days
4- fluid therapy (very very important) :
2 liter saline + 3 liter glucose 5 % / I.V

N.B: *addition of bran & bone meal to the ration during
barseem season
*if the cow recumbent before calving → give it
phosphorus therapy as APROPHYLACTIC

D.D
Red urine

hematuria

Hemoglobin uria

Myoglobin uria

Urine sample
Sedimentation (centrifugation)

*presence of sediment:
it is hematouria
microscopical exam → intact RBCs

Presence of homogenous & transparent
fluid :
It may be

Hb uria
Myoglobinuria

-If presence of homogenous & transparent fluid :
you may take serum sample & see its color :
*if it is of pink color → Hb uria
*if it is of clear color → Myoglobin uria

**Hb uria (caused by )
1- Babesia → -tick infestation
-young age more susceptible
-profuse diarrhea (pipe steam diarrhea) ,
then constipation
-M.M → congested → pale → jundice
-blood film → parasite

2-Bacillary Hb:
-sudden death (every 3 days)
-high fever
-sudden drop in milk yield
-blood stained feces
-necrosis in liver ( p.m)
- most common with liver fluke infestation
&during summer

3-Leptospira:
-calves & lambs are more susceptible than
adult
-pyrexia (41-42ºc) → abortion
-high mortality rate in calves & lambs
-bloody milk from all qurters
-the udder is soft & flappy

4-copper poisoning
-no fever

-severe jaundice

5-water intoxication
-history of ingestion of large amount of cold
water

6-hypophosphatemia
***Hematouria (caused by)
1-pyelonephritis
-fever in acute
-urine contain RBCs & pus cell
-rectally → pain , enlargement of kidney , absence of
its lobulation , cord like urter
-frequent , painful urination
-vaginal purulent discharge

2-Cystitis
-rectally is → thickening in wall of U.B &
painful in acute
-urine → has RBCs & pus cell
-frequent , painful urination

3-Urolithiasis
-in castrated male ruminant (fattening)
-retention of urine (auria)
-few drop of blood stained urine
-rectally → distention of U.B

4-Enzootic hematouria (neoplasm in U.B)
-affect old age only
-persistent red urine for long period of time
-presence of blood clots in urine

Thank you
and
Good luck


Slide 5

Post parturient hemoglobinuria
(PPH)

**it is common occur in highly producing dairy cows in the
1st 2-4 weeks after calving & in the 5th – 7th month of
pregnancy in buffaloes .
**age of susceptibility → 3rd – 6th calving.
**It is caused by low phosphorus level in the blood resulting
from low phosphorus intake either by ration or grazing on
pasture for long period 3-4 months as barseem.
**The diseases mainly occur in winter as the animals
feeding mainly on barseem (Nov.- May.). Addition of
bran and bone meal to the ration are necessary during
barseem season.

Clinical signs
-Hb uria (urine color → light brown or reddish or coffee)
-anorexia , pica, severe decrease of milk yield , loss of b.wt &
.weakness
-secondary ketosis
-dehydration
-pale M.M → then jaundice with normal body temperature
-the course of disease → 3-5 days in standing position →
followed by weakness & sternal recumbancy for 3-5 days
-in chronic case → ketosis & locomotors disturbance

Treatment
1- in severe anemia → blood transfusion (4-5 liter)
2-give source of phosphorus :
a- Sod.dibasic phosphate or Sod.acid phosphate → 60 gm
/ 300 ml D.W filtred and given /I.V → followed by S/C dose
after 12 hr for 3-5days . Also , oral dose (80 gm ) / daily / till 3
days after recovery
b- give patent preparation as :
-Catozal , cafozal, phosphozal → 50 cm / I.V/ daily /
3-5 days.
-Tonophosphan → 50 cm / I.V / daily/ 3-5 days
3 -Arsinal 15 cc I/M daily / 3 days
4- fluid therapy (very very important) :
2 liter saline + 3 liter glucose 5 % / I.V

N.B: *addition of bran & bone meal to the ration during
barseem season
*if the cow recumbent before calving → give it
phosphorus therapy as APROPHYLACTIC

D.D
Red urine

hematuria

Hemoglobin uria

Myoglobin uria

Urine sample
Sedimentation (centrifugation)

*presence of sediment:
it is hematouria
microscopical exam → intact RBCs

Presence of homogenous & transparent
fluid :
It may be

Hb uria
Myoglobinuria

-If presence of homogenous & transparent fluid :
you may take serum sample & see its color :
*if it is of pink color → Hb uria
*if it is of clear color → Myoglobin uria

**Hb uria (caused by )
1- Babesia → -tick infestation
-young age more susceptible
-profuse diarrhea (pipe steam diarrhea) ,
then constipation
-M.M → congested → pale → jundice
-blood film → parasite

2-Bacillary Hb:
-sudden death (every 3 days)
-high fever
-sudden drop in milk yield
-blood stained feces
-necrosis in liver ( p.m)
- most common with liver fluke infestation
&during summer

3-Leptospira:
-calves & lambs are more susceptible than
adult
-pyrexia (41-42ºc) → abortion
-high mortality rate in calves & lambs
-bloody milk from all qurters
-the udder is soft & flappy

4-copper poisoning
-no fever

-severe jaundice

5-water intoxication
-history of ingestion of large amount of cold
water

6-hypophosphatemia
***Hematouria (caused by)
1-pyelonephritis
-fever in acute
-urine contain RBCs & pus cell
-rectally → pain , enlargement of kidney , absence of
its lobulation , cord like urter
-frequent , painful urination
-vaginal purulent discharge

2-Cystitis
-rectally is → thickening in wall of U.B &
painful in acute
-urine → has RBCs & pus cell
-frequent , painful urination

3-Urolithiasis
-in castrated male ruminant (fattening)
-retention of urine (auria)
-few drop of blood stained urine
-rectally → distention of U.B

4-Enzootic hematouria (neoplasm in U.B)
-affect old age only
-persistent red urine for long period of time
-presence of blood clots in urine

Thank you
and
Good luck


Slide 6

Post parturient hemoglobinuria
(PPH)

**it is common occur in highly producing dairy cows in the
1st 2-4 weeks after calving & in the 5th – 7th month of
pregnancy in buffaloes .
**age of susceptibility → 3rd – 6th calving.
**It is caused by low phosphorus level in the blood resulting
from low phosphorus intake either by ration or grazing on
pasture for long period 3-4 months as barseem.
**The diseases mainly occur in winter as the animals
feeding mainly on barseem (Nov.- May.). Addition of
bran and bone meal to the ration are necessary during
barseem season.

Clinical signs
-Hb uria (urine color → light brown or reddish or coffee)
-anorexia , pica, severe decrease of milk yield , loss of b.wt &
.weakness
-secondary ketosis
-dehydration
-pale M.M → then jaundice with normal body temperature
-the course of disease → 3-5 days in standing position →
followed by weakness & sternal recumbancy for 3-5 days
-in chronic case → ketosis & locomotors disturbance

Treatment
1- in severe anemia → blood transfusion (4-5 liter)
2-give source of phosphorus :
a- Sod.dibasic phosphate or Sod.acid phosphate → 60 gm
/ 300 ml D.W filtred and given /I.V → followed by S/C dose
after 12 hr for 3-5days . Also , oral dose (80 gm ) / daily / till 3
days after recovery
b- give patent preparation as :
-Catozal , cafozal, phosphozal → 50 cm / I.V/ daily /
3-5 days.
-Tonophosphan → 50 cm / I.V / daily/ 3-5 days
3 -Arsinal 15 cc I/M daily / 3 days
4- fluid therapy (very very important) :
2 liter saline + 3 liter glucose 5 % / I.V

N.B: *addition of bran & bone meal to the ration during
barseem season
*if the cow recumbent before calving → give it
phosphorus therapy as APROPHYLACTIC

D.D
Red urine

hematuria

Hemoglobin uria

Myoglobin uria

Urine sample
Sedimentation (centrifugation)

*presence of sediment:
it is hematouria
microscopical exam → intact RBCs

Presence of homogenous & transparent
fluid :
It may be

Hb uria
Myoglobinuria

-If presence of homogenous & transparent fluid :
you may take serum sample & see its color :
*if it is of pink color → Hb uria
*if it is of clear color → Myoglobin uria

**Hb uria (caused by )
1- Babesia → -tick infestation
-young age more susceptible
-profuse diarrhea (pipe steam diarrhea) ,
then constipation
-M.M → congested → pale → jundice
-blood film → parasite

2-Bacillary Hb:
-sudden death (every 3 days)
-high fever
-sudden drop in milk yield
-blood stained feces
-necrosis in liver ( p.m)
- most common with liver fluke infestation
&during summer

3-Leptospira:
-calves & lambs are more susceptible than
adult
-pyrexia (41-42ºc) → abortion
-high mortality rate in calves & lambs
-bloody milk from all qurters
-the udder is soft & flappy

4-copper poisoning
-no fever

-severe jaundice

5-water intoxication
-history of ingestion of large amount of cold
water

6-hypophosphatemia
***Hematouria (caused by)
1-pyelonephritis
-fever in acute
-urine contain RBCs & pus cell
-rectally → pain , enlargement of kidney , absence of
its lobulation , cord like urter
-frequent , painful urination
-vaginal purulent discharge

2-Cystitis
-rectally is → thickening in wall of U.B &
painful in acute
-urine → has RBCs & pus cell
-frequent , painful urination

3-Urolithiasis
-in castrated male ruminant (fattening)
-retention of urine (auria)
-few drop of blood stained urine
-rectally → distention of U.B

4-Enzootic hematouria (neoplasm in U.B)
-affect old age only
-persistent red urine for long period of time
-presence of blood clots in urine

Thank you
and
Good luck


Slide 7

Post parturient hemoglobinuria
(PPH)

**it is common occur in highly producing dairy cows in the
1st 2-4 weeks after calving & in the 5th – 7th month of
pregnancy in buffaloes .
**age of susceptibility → 3rd – 6th calving.
**It is caused by low phosphorus level in the blood resulting
from low phosphorus intake either by ration or grazing on
pasture for long period 3-4 months as barseem.
**The diseases mainly occur in winter as the animals
feeding mainly on barseem (Nov.- May.). Addition of
bran and bone meal to the ration are necessary during
barseem season.

Clinical signs
-Hb uria (urine color → light brown or reddish or coffee)
-anorexia , pica, severe decrease of milk yield , loss of b.wt &
.weakness
-secondary ketosis
-dehydration
-pale M.M → then jaundice with normal body temperature
-the course of disease → 3-5 days in standing position →
followed by weakness & sternal recumbancy for 3-5 days
-in chronic case → ketosis & locomotors disturbance

Treatment
1- in severe anemia → blood transfusion (4-5 liter)
2-give source of phosphorus :
a- Sod.dibasic phosphate or Sod.acid phosphate → 60 gm
/ 300 ml D.W filtred and given /I.V → followed by S/C dose
after 12 hr for 3-5days . Also , oral dose (80 gm ) / daily / till 3
days after recovery
b- give patent preparation as :
-Catozal , cafozal, phosphozal → 50 cm / I.V/ daily /
3-5 days.
-Tonophosphan → 50 cm / I.V / daily/ 3-5 days
3 -Arsinal 15 cc I/M daily / 3 days
4- fluid therapy (very very important) :
2 liter saline + 3 liter glucose 5 % / I.V

N.B: *addition of bran & bone meal to the ration during
barseem season
*if the cow recumbent before calving → give it
phosphorus therapy as APROPHYLACTIC

D.D
Red urine

hematuria

Hemoglobin uria

Myoglobin uria

Urine sample
Sedimentation (centrifugation)

*presence of sediment:
it is hematouria
microscopical exam → intact RBCs

Presence of homogenous & transparent
fluid :
It may be

Hb uria
Myoglobinuria

-If presence of homogenous & transparent fluid :
you may take serum sample & see its color :
*if it is of pink color → Hb uria
*if it is of clear color → Myoglobin uria

**Hb uria (caused by )
1- Babesia → -tick infestation
-young age more susceptible
-profuse diarrhea (pipe steam diarrhea) ,
then constipation
-M.M → congested → pale → jundice
-blood film → parasite

2-Bacillary Hb:
-sudden death (every 3 days)
-high fever
-sudden drop in milk yield
-blood stained feces
-necrosis in liver ( p.m)
- most common with liver fluke infestation
&during summer

3-Leptospira:
-calves & lambs are more susceptible than
adult
-pyrexia (41-42ºc) → abortion
-high mortality rate in calves & lambs
-bloody milk from all qurters
-the udder is soft & flappy

4-copper poisoning
-no fever

-severe jaundice

5-water intoxication
-history of ingestion of large amount of cold
water

6-hypophosphatemia
***Hematouria (caused by)
1-pyelonephritis
-fever in acute
-urine contain RBCs & pus cell
-rectally → pain , enlargement of kidney , absence of
its lobulation , cord like urter
-frequent , painful urination
-vaginal purulent discharge

2-Cystitis
-rectally is → thickening in wall of U.B &
painful in acute
-urine → has RBCs & pus cell
-frequent , painful urination

3-Urolithiasis
-in castrated male ruminant (fattening)
-retention of urine (auria)
-few drop of blood stained urine
-rectally → distention of U.B

4-Enzootic hematouria (neoplasm in U.B)
-affect old age only
-persistent red urine for long period of time
-presence of blood clots in urine

Thank you
and
Good luck


Slide 8

Post parturient hemoglobinuria
(PPH)

**it is common occur in highly producing dairy cows in the
1st 2-4 weeks after calving & in the 5th – 7th month of
pregnancy in buffaloes .
**age of susceptibility → 3rd – 6th calving.
**It is caused by low phosphorus level in the blood resulting
from low phosphorus intake either by ration or grazing on
pasture for long period 3-4 months as barseem.
**The diseases mainly occur in winter as the animals
feeding mainly on barseem (Nov.- May.). Addition of
bran and bone meal to the ration are necessary during
barseem season.

Clinical signs
-Hb uria (urine color → light brown or reddish or coffee)
-anorexia , pica, severe decrease of milk yield , loss of b.wt &
.weakness
-secondary ketosis
-dehydration
-pale M.M → then jaundice with normal body temperature
-the course of disease → 3-5 days in standing position →
followed by weakness & sternal recumbancy for 3-5 days
-in chronic case → ketosis & locomotors disturbance

Treatment
1- in severe anemia → blood transfusion (4-5 liter)
2-give source of phosphorus :
a- Sod.dibasic phosphate or Sod.acid phosphate → 60 gm
/ 300 ml D.W filtred and given /I.V → followed by S/C dose
after 12 hr for 3-5days . Also , oral dose (80 gm ) / daily / till 3
days after recovery
b- give patent preparation as :
-Catozal , cafozal, phosphozal → 50 cm / I.V/ daily /
3-5 days.
-Tonophosphan → 50 cm / I.V / daily/ 3-5 days
3 -Arsinal 15 cc I/M daily / 3 days
4- fluid therapy (very very important) :
2 liter saline + 3 liter glucose 5 % / I.V

N.B: *addition of bran & bone meal to the ration during
barseem season
*if the cow recumbent before calving → give it
phosphorus therapy as APROPHYLACTIC

D.D
Red urine

hematuria

Hemoglobin uria

Myoglobin uria

Urine sample
Sedimentation (centrifugation)

*presence of sediment:
it is hematouria
microscopical exam → intact RBCs

Presence of homogenous & transparent
fluid :
It may be

Hb uria
Myoglobinuria

-If presence of homogenous & transparent fluid :
you may take serum sample & see its color :
*if it is of pink color → Hb uria
*if it is of clear color → Myoglobin uria

**Hb uria (caused by )
1- Babesia → -tick infestation
-young age more susceptible
-profuse diarrhea (pipe steam diarrhea) ,
then constipation
-M.M → congested → pale → jundice
-blood film → parasite

2-Bacillary Hb:
-sudden death (every 3 days)
-high fever
-sudden drop in milk yield
-blood stained feces
-necrosis in liver ( p.m)
- most common with liver fluke infestation
&during summer

3-Leptospira:
-calves & lambs are more susceptible than
adult
-pyrexia (41-42ºc) → abortion
-high mortality rate in calves & lambs
-bloody milk from all qurters
-the udder is soft & flappy

4-copper poisoning
-no fever

-severe jaundice

5-water intoxication
-history of ingestion of large amount of cold
water

6-hypophosphatemia
***Hematouria (caused by)
1-pyelonephritis
-fever in acute
-urine contain RBCs & pus cell
-rectally → pain , enlargement of kidney , absence of
its lobulation , cord like urter
-frequent , painful urination
-vaginal purulent discharge

2-Cystitis
-rectally is → thickening in wall of U.B &
painful in acute
-urine → has RBCs & pus cell
-frequent , painful urination

3-Urolithiasis
-in castrated male ruminant (fattening)
-retention of urine (auria)
-few drop of blood stained urine
-rectally → distention of U.B

4-Enzootic hematouria (neoplasm in U.B)
-affect old age only
-persistent red urine for long period of time
-presence of blood clots in urine

Thank you
and
Good luck


Slide 9

Post parturient hemoglobinuria
(PPH)

**it is common occur in highly producing dairy cows in the
1st 2-4 weeks after calving & in the 5th – 7th month of
pregnancy in buffaloes .
**age of susceptibility → 3rd – 6th calving.
**It is caused by low phosphorus level in the blood resulting
from low phosphorus intake either by ration or grazing on
pasture for long period 3-4 months as barseem.
**The diseases mainly occur in winter as the animals
feeding mainly on barseem (Nov.- May.). Addition of
bran and bone meal to the ration are necessary during
barseem season.

Clinical signs
-Hb uria (urine color → light brown or reddish or coffee)
-anorexia , pica, severe decrease of milk yield , loss of b.wt &
.weakness
-secondary ketosis
-dehydration
-pale M.M → then jaundice with normal body temperature
-the course of disease → 3-5 days in standing position →
followed by weakness & sternal recumbancy for 3-5 days
-in chronic case → ketosis & locomotors disturbance

Treatment
1- in severe anemia → blood transfusion (4-5 liter)
2-give source of phosphorus :
a- Sod.dibasic phosphate or Sod.acid phosphate → 60 gm
/ 300 ml D.W filtred and given /I.V → followed by S/C dose
after 12 hr for 3-5days . Also , oral dose (80 gm ) / daily / till 3
days after recovery
b- give patent preparation as :
-Catozal , cafozal, phosphozal → 50 cm / I.V/ daily /
3-5 days.
-Tonophosphan → 50 cm / I.V / daily/ 3-5 days
3 -Arsinal 15 cc I/M daily / 3 days
4- fluid therapy (very very important) :
2 liter saline + 3 liter glucose 5 % / I.V

N.B: *addition of bran & bone meal to the ration during
barseem season
*if the cow recumbent before calving → give it
phosphorus therapy as APROPHYLACTIC

D.D
Red urine

hematuria

Hemoglobin uria

Myoglobin uria

Urine sample
Sedimentation (centrifugation)

*presence of sediment:
it is hematouria
microscopical exam → intact RBCs

Presence of homogenous & transparent
fluid :
It may be

Hb uria
Myoglobinuria

-If presence of homogenous & transparent fluid :
you may take serum sample & see its color :
*if it is of pink color → Hb uria
*if it is of clear color → Myoglobin uria

**Hb uria (caused by )
1- Babesia → -tick infestation
-young age more susceptible
-profuse diarrhea (pipe steam diarrhea) ,
then constipation
-M.M → congested → pale → jundice
-blood film → parasite

2-Bacillary Hb:
-sudden death (every 3 days)
-high fever
-sudden drop in milk yield
-blood stained feces
-necrosis in liver ( p.m)
- most common with liver fluke infestation
&during summer

3-Leptospira:
-calves & lambs are more susceptible than
adult
-pyrexia (41-42ºc) → abortion
-high mortality rate in calves & lambs
-bloody milk from all qurters
-the udder is soft & flappy

4-copper poisoning
-no fever

-severe jaundice

5-water intoxication
-history of ingestion of large amount of cold
water

6-hypophosphatemia
***Hematouria (caused by)
1-pyelonephritis
-fever in acute
-urine contain RBCs & pus cell
-rectally → pain , enlargement of kidney , absence of
its lobulation , cord like urter
-frequent , painful urination
-vaginal purulent discharge

2-Cystitis
-rectally is → thickening in wall of U.B &
painful in acute
-urine → has RBCs & pus cell
-frequent , painful urination

3-Urolithiasis
-in castrated male ruminant (fattening)
-retention of urine (auria)
-few drop of blood stained urine
-rectally → distention of U.B

4-Enzootic hematouria (neoplasm in U.B)
-affect old age only
-persistent red urine for long period of time
-presence of blood clots in urine

Thank you
and
Good luck


Slide 10

Post parturient hemoglobinuria
(PPH)

**it is common occur in highly producing dairy cows in the
1st 2-4 weeks after calving & in the 5th – 7th month of
pregnancy in buffaloes .
**age of susceptibility → 3rd – 6th calving.
**It is caused by low phosphorus level in the blood resulting
from low phosphorus intake either by ration or grazing on
pasture for long period 3-4 months as barseem.
**The diseases mainly occur in winter as the animals
feeding mainly on barseem (Nov.- May.). Addition of
bran and bone meal to the ration are necessary during
barseem season.

Clinical signs
-Hb uria (urine color → light brown or reddish or coffee)
-anorexia , pica, severe decrease of milk yield , loss of b.wt &
.weakness
-secondary ketosis
-dehydration
-pale M.M → then jaundice with normal body temperature
-the course of disease → 3-5 days in standing position →
followed by weakness & sternal recumbancy for 3-5 days
-in chronic case → ketosis & locomotors disturbance

Treatment
1- in severe anemia → blood transfusion (4-5 liter)
2-give source of phosphorus :
a- Sod.dibasic phosphate or Sod.acid phosphate → 60 gm
/ 300 ml D.W filtred and given /I.V → followed by S/C dose
after 12 hr for 3-5days . Also , oral dose (80 gm ) / daily / till 3
days after recovery
b- give patent preparation as :
-Catozal , cafozal, phosphozal → 50 cm / I.V/ daily /
3-5 days.
-Tonophosphan → 50 cm / I.V / daily/ 3-5 days
3 -Arsinal 15 cc I/M daily / 3 days
4- fluid therapy (very very important) :
2 liter saline + 3 liter glucose 5 % / I.V

N.B: *addition of bran & bone meal to the ration during
barseem season
*if the cow recumbent before calving → give it
phosphorus therapy as APROPHYLACTIC

D.D
Red urine

hematuria

Hemoglobin uria

Myoglobin uria

Urine sample
Sedimentation (centrifugation)

*presence of sediment:
it is hematouria
microscopical exam → intact RBCs

Presence of homogenous & transparent
fluid :
It may be

Hb uria
Myoglobinuria

-If presence of homogenous & transparent fluid :
you may take serum sample & see its color :
*if it is of pink color → Hb uria
*if it is of clear color → Myoglobin uria

**Hb uria (caused by )
1- Babesia → -tick infestation
-young age more susceptible
-profuse diarrhea (pipe steam diarrhea) ,
then constipation
-M.M → congested → pale → jundice
-blood film → parasite

2-Bacillary Hb:
-sudden death (every 3 days)
-high fever
-sudden drop in milk yield
-blood stained feces
-necrosis in liver ( p.m)
- most common with liver fluke infestation
&during summer

3-Leptospira:
-calves & lambs are more susceptible than
adult
-pyrexia (41-42ºc) → abortion
-high mortality rate in calves & lambs
-bloody milk from all qurters
-the udder is soft & flappy

4-copper poisoning
-no fever

-severe jaundice

5-water intoxication
-history of ingestion of large amount of cold
water

6-hypophosphatemia
***Hematouria (caused by)
1-pyelonephritis
-fever in acute
-urine contain RBCs & pus cell
-rectally → pain , enlargement of kidney , absence of
its lobulation , cord like urter
-frequent , painful urination
-vaginal purulent discharge

2-Cystitis
-rectally is → thickening in wall of U.B &
painful in acute
-urine → has RBCs & pus cell
-frequent , painful urination

3-Urolithiasis
-in castrated male ruminant (fattening)
-retention of urine (auria)
-few drop of blood stained urine
-rectally → distention of U.B

4-Enzootic hematouria (neoplasm in U.B)
-affect old age only
-persistent red urine for long period of time
-presence of blood clots in urine

Thank you
and
Good luck


Slide 11

Post parturient hemoglobinuria
(PPH)

**it is common occur in highly producing dairy cows in the
1st 2-4 weeks after calving & in the 5th – 7th month of
pregnancy in buffaloes .
**age of susceptibility → 3rd – 6th calving.
**It is caused by low phosphorus level in the blood resulting
from low phosphorus intake either by ration or grazing on
pasture for long period 3-4 months as barseem.
**The diseases mainly occur in winter as the animals
feeding mainly on barseem (Nov.- May.). Addition of
bran and bone meal to the ration are necessary during
barseem season.

Clinical signs
-Hb uria (urine color → light brown or reddish or coffee)
-anorexia , pica, severe decrease of milk yield , loss of b.wt &
.weakness
-secondary ketosis
-dehydration
-pale M.M → then jaundice with normal body temperature
-the course of disease → 3-5 days in standing position →
followed by weakness & sternal recumbancy for 3-5 days
-in chronic case → ketosis & locomotors disturbance

Treatment
1- in severe anemia → blood transfusion (4-5 liter)
2-give source of phosphorus :
a- Sod.dibasic phosphate or Sod.acid phosphate → 60 gm
/ 300 ml D.W filtred and given /I.V → followed by S/C dose
after 12 hr for 3-5days . Also , oral dose (80 gm ) / daily / till 3
days after recovery
b- give patent preparation as :
-Catozal , cafozal, phosphozal → 50 cm / I.V/ daily /
3-5 days.
-Tonophosphan → 50 cm / I.V / daily/ 3-5 days
3 -Arsinal 15 cc I/M daily / 3 days
4- fluid therapy (very very important) :
2 liter saline + 3 liter glucose 5 % / I.V

N.B: *addition of bran & bone meal to the ration during
barseem season
*if the cow recumbent before calving → give it
phosphorus therapy as APROPHYLACTIC

D.D
Red urine

hematuria

Hemoglobin uria

Myoglobin uria

Urine sample
Sedimentation (centrifugation)

*presence of sediment:
it is hematouria
microscopical exam → intact RBCs

Presence of homogenous & transparent
fluid :
It may be

Hb uria
Myoglobinuria

-If presence of homogenous & transparent fluid :
you may take serum sample & see its color :
*if it is of pink color → Hb uria
*if it is of clear color → Myoglobin uria

**Hb uria (caused by )
1- Babesia → -tick infestation
-young age more susceptible
-profuse diarrhea (pipe steam diarrhea) ,
then constipation
-M.M → congested → pale → jundice
-blood film → parasite

2-Bacillary Hb:
-sudden death (every 3 days)
-high fever
-sudden drop in milk yield
-blood stained feces
-necrosis in liver ( p.m)
- most common with liver fluke infestation
&during summer

3-Leptospira:
-calves & lambs are more susceptible than
adult
-pyrexia (41-42ºc) → abortion
-high mortality rate in calves & lambs
-bloody milk from all qurters
-the udder is soft & flappy

4-copper poisoning
-no fever

-severe jaundice

5-water intoxication
-history of ingestion of large amount of cold
water

6-hypophosphatemia
***Hematouria (caused by)
1-pyelonephritis
-fever in acute
-urine contain RBCs & pus cell
-rectally → pain , enlargement of kidney , absence of
its lobulation , cord like urter
-frequent , painful urination
-vaginal purulent discharge

2-Cystitis
-rectally is → thickening in wall of U.B &
painful in acute
-urine → has RBCs & pus cell
-frequent , painful urination

3-Urolithiasis
-in castrated male ruminant (fattening)
-retention of urine (auria)
-few drop of blood stained urine
-rectally → distention of U.B

4-Enzootic hematouria (neoplasm in U.B)
-affect old age only
-persistent red urine for long period of time
-presence of blood clots in urine

Thank you
and
Good luck