Conformal Geometry Based Supine and Prone Colon Registration Wei Zeng Joseph Marino Xianfeng Gu Arie Kaufman Stony Brook University, New York, USA The MICCAI.
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Conformal Geometry Based Supine and Prone Colon Registration Wei Zeng Joseph Marino Xianfeng Gu Arie Kaufman Stony Brook University, New York, USA The MICCAI 2010 Workshop on Virtual Colonoscopy and Abdominal Imaging 2010-09-20 Overview • Problem - Supine and Prone Colon Registration – Challenge: Non-rigid deformation and substantial distortion, due to position shifting • Solution - Conformal Mapping Based Registration – Formulation: Matching between 3D topological cylinders – Key: 3D => 2D matching problem – Goal: One-to-one map • Contribution - Diffeomorphism between Surfaces – Advantage: Guarantee one-to-one map of whole surface – Efficiency: Linear time complexity 2 Algorithm Anatomical Landmark Extraction Supine & Prone Colon Surfaces (S1, S2) Conformal Mapping (φ1, φ2) Holomorphic Differentials Internal Feature Detection & Matching Harmonic Map Registration Constraints: Feature Correspondence of (S1, S2) Harmonic Energy Linear System Optimization 3 Anatomical Landmarks Extraction • Idea: Extract anatomical landmarks using existing methods – Taenia coli – Slicing the colon surface open – Flexures – Dividing the colon to 5 segments Taenia Coli Flexures 4 Conformal Map - Holomorphic Differentials • Idea: Solve harmonic functions with Dirichlet boundary conditions. – Colon segment: topological cylinder, denoted as triangular mesh 3D Surface 2D Conformal Map Texture Map Non-rigid Deformation Different Conformal Modules Angle Preserving 5 Internal Feature Detection and Matching • Idea: Perform detection and matching on conformal mapping images color encoded by mean curvature of 3D surface. – Method: 1) Graph Cut Segmentation and 2) Graph Matching methods 2D Conformal Map Segmentation Extraction Matching Mean Curvature Haustral Folds Feature Points Feature Correspondence 6 Conformal Map - Matching Framework 3D Surface 2D Conformal Map 3D Surface 2D Conformal Map 7 Conformal Map Based Surface Matching • Idea: Compute harmonic map between two 2D maps with feature correspondence constraints – One-to-one mapping – Linear computational complexity Polyp on Supine Supine => Prone Deformed Supine Polyp on Prone Registration 8 Experiments • Data – National Institute of Biomedical Imaging and Bioengineering (NIBIB) Image and Clinical Data Repository, provided by the National Institute of Health (NIH) • Registration Accuracy – Averaged distance error in R3 (mm) – Better than existing centerline-based methods, similar to [4] • Advantage: One-to-one surface registration Table 1. Comparison of average millimeter distance error between existing methods. Methods Distance Error Our Conformal Geometry Based Method 7.85mm Haustral fold registration [4] 5.03 mm Centerline registration + statistical analysis [12] 12.66mm Linear stretching / shrinking of centerline [1] 13.20mm Centerline feature matching + lumen deformation [14] 13.77mm Centerline point correlation [3] 20.00mm Taenia coli correlation [10] 23.33mm 9 Conclusion • Conformal Geometry for Supine-Prone Registration – 3D problem => 2D matching problem – Internal feature correspondence based on 2D conformal mapping images color encoded by mean curvature. – Surface registration by harmonic map with feature correspondences, not only the feature points. • Advantage – One-to-one and onto surface registration (diffeomorphism) – Efficiency: linear time complexity – Accuracy: low averaged distance error 10 Questions? Thanks! 11