Transcript Percentage of Non-susceptible Sterile Site vs Non

Figure 1. Percentage of Penicillin Non-Susceptible
S. pneumoniae in Canada: 1988-2007
18
% intermediate resistance
16
% high-level resistance
14
12
10
8
6
4
2
0
1988
1993
1995
1997
1999
2001
2003
2005
2007
Canadian Bacterial Surveillance Network, March 2008
Figure 2. Percentage of Non-susceptible Sterile Site vs
Non-sterile Site Isolates of S. pneumoniae, 2007
25
Sterile
Percentage (%) Non-susceptible
Non-sterile
20
15
10
5
0
Pen
Erythro
Clinda
Ceftriaxone
Cipro
Tmp/Smx
Tetracycline
Canadian Bacterial Surveillance Network, March 2008
Figure 3. Percentage of Non-susceptible Isolates of
S. pneumoniae in Ages <=15 and >64, 2007
25
Age <=15 yrs
Percentage (%) non-susceptible
Age >64 yrs
20
15
10
5
0
Pen
Erythro
Clinda
Ceftriaxone
Cipro
Tmp/Smx
Tetracycline
Canadian Bacterial Surveillance Network, March 2008
Figure 4. Percentage of Non-susceptible Isolates of
S. pneumoniae in Geographic Regions of Canada, 2007
30
25
20
15
10
5
0
BC
PRAIRIES
Levo
ONT
Ceftri (Non-mening)
QUE
Clind
Atlantic
Pen
Eryth
Canadian Bacterial Surveillance Network, March 2008
Figure 5. Macrolide-Resistant Pneumococci: Canadian
Bacterial Surveillance Network, 1988-2007
Percentage of Isolates Resistant to
Erythromycin
25
20
15
10
5
0
1988
1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007
Canadian Bacterial Surveillance Network, March 2008
Figure 6. Fluoroquinolone-Resistant Pneumococci:
Canadian Bacterial Surveillance Network, 1997-2007
Moxifloxacin
% Resistant
2
Levofloxacin
1.5
1
0.5
0
1997
1998
1999
2000
2001 2002
2003
2004
2005
2006
2007
Canadian Bacterial Surveillance Network, March 2008
Figure 7. Fluoroquinolone-Resistant Pneumococci in
Respiratory Isolates from Adults >64 years: 1988-2007
4.5
3.5
Levofloxacin
Moxifloxacin
3
2.5
2
1.5
1
% Resistant isolates
4
0.5
2007
2006
2005
2004
2003
2002
2001
2000
1999
1998
1997
1996
1995
1994
1993
1988
0
Year
Canadian Bacterial Surveillance Network, March 2008
Figure 8. Ceftriaxone-Resistant Pneumococci: Canadian
Bacterial Surveillance Network, 1988-2007
4
% Intermediate Resistance
3.5
% High-level Resistance
3
2.5
2
1.5
1
0.5
0
1988
1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007
*Non-meningitis breakpoints used
Canadian Bacterial Surveillance Network, March 2008