Transcript Chapter 17
CH 17 – WBC Morphology Five Types of Leukocytes (WBCs) Granular Leukocytes Eosinophil Neutrophil Basophil Neutrophil 60-70% of all WBC’s Anatomy 10-12 µm diameter 2-6 nuclear lobes Fine, pale inconspicuous granules Physiology Respond first to bacteria damage by chemotaxis Phagocytosis After engulfing pathogen releases several chemicals lysozyme strong oxidants defensins Eosinophil 2-4% of all WBC’s Anatomy 10-12 µm diameter 2 connected nuclear lobes red/orange large, uniform granules, do not obscure the nucleus Physiology exit capillaries, enter tissue fluid combat parasites histamine phagocytize antigenantibody complexes Basophil 0.5-1% of all WBC’s Anatomy 8-10 µm diameter bilobed or irregular nucleus round, blue-black granules may obscure the nucleus Physiology exit capillaries to enter tissue fluid mature into mast cells release heparin, histamine, serotonin – stimulate inflammation Hypersensitivity (allergic) reactions Agranular Leukocytes Lymphocyte Monocyte Lymphocytes 20-25% of all WBC’s Anatomy 7-15µm nucleus large and dark stained, round or indented cytoplasm forms a pale blue rim around the nucleus Monocytes 3-8% of all WBC’s Anatomy 14-19 µm indented or kidney-shaped nucleus (not round) cytoplasm foamy Physiology slower to arrive but survive longer enlarge, differentiate into fixed and wandering macrophages remove microbes, cellular debris, following injury End WBC Morphology CH 17