Transcript Bio 449 Lecture 3 Outline Aug. 30, 2008

Bio 449
Lecture 24
Blood Gas Transport I
Diffusion of gases
Alveolar-blood gradients
Oxygen transport
Oxygen affinity
Modifiers of oxygen affinity
Two pigment systems
Carbon Dioxide Transport
Control of Ventilation
Generation of rhythmic breathing
Regulation of blood gases
Effects of PCO2
Effects of PO2
Other factors affecting ventilation
Lectures 23-24:
Lectures 25-27:
Nov. 3, 2010
Terms to Know
Oxygen carrying capacity
Oxygen affinity
Oxygen saturation curve
Bohr effect
Right-shift
2,3-DPG (2,3-diphosphoglycerate)
Two pigment system
Myoglobin (Mb)
Carbamino compounds
Carbonic anhydrase
Bicarbonate
Peripheral chemoreceptors
Central chemoreceptors
Carotid bodies
Aortic bodies
Blood-brain barrier
Readings
Chapter 16, pages 547-558
Chapter 18
Chapters 19 & 20
Diffusion of gases
Oxygen transport
Oxygen affinity
Modifiers of oxygen affinity
Two pigment systems
Carbon dioxide transport
Control of Ventilation
Generation of rhythmic breathing
Control centers
KEY
DRG = Dorsal respiratory group
VRG = Ventral respiratory group
Higher
brain
centers
Pons
Medullary
chemoreceptors
Peripheral
chemoreceptors
DRG
Medulla
pre-Bötzinger
complex
VRG
Fig. 18-17
Output to expiratory,
some inspiratory,
pharynx, larynx, and
tongue muscles
Output
primarily to
inspiratory
muscles
Regulation of blood gases