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Principles of
Pharmacology
The Pathophysiologic
Basis of Drug
Therapy
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Chapter 6
Pharmacogenomics
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
CYP2D6 Pharmacogenetics
• Figure 6-1
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Tamoxifen Pharmacogenetics
• Figure 6-2
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
TPMT Pharmacogenetics
• Figure 6-3
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Warfarin Pharmacokinetics and
Pharmacodynamics
• Figure 6-4
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Genome-Wide Association Study
of Statin-Induced Myopathy
• Figure 6-5
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins