Transcript Preliminary Concepts of the Interlaboratory Testing Group

Interlaboratory Testing:
Preliminary Concepts
Carolyn Cairns and Janet Carter
16 May 2013
Purpose for the Workshop
• Present framework for ITG testing
– Develop recommendations on specifics for testing
strategy
–Workshop will provide solid recommendations
to steering committee on path forward for ITG
• Identify critical considerations for interlaboratory testing
ITG Charge
To develop a testing strategy* to assess
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Robustness
Reproducibility
Repeatability
Transferability
of analytical methods available to detect
nanoscale releases from selected nanocomposites
for priority release scenarios
*based on TG and SOS white papers
Initial Approach
• Small pilot project to explore feasibility of interlaboratory testing
– Quickly identify inconsistencies or deficiencies
– Fine tune methods for broader testing
• Design appropriate analytical and process
controls
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–
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Creation and transport of samples
Identification of MWCNT
Polymer and polymer/MWCNT
Standardized material as laboratory control
Positive and negative controls
Module
A. Abrasion/
Consumer
B. Sanding/
Occupational
Materials
(CNT/Polymers)
Suppliers
Identify
specific
scenarios and
CNT/polymer
for consumer
and
occupational
settings
Sample
Generation
Lab A
Lab B
Analytical
Methods
Development
(e.g. particle
count, SEM, AUC,
etc.)
Lab A
Lab C
Lab B
Lab D
C. Weathering/
Environmental
CNT/polymer
specific to
uses subject to
weathering
Lab E
Break Out Sessions
• Make decisions regarding materials, scenarios,
and methods to be used in Phase 3 – the
interlaboratory testing
– Decisions based on information obtained in TGs
and SOS as well as Phase 2.5 document
• Recommendations from breakout sessions will
be sent back to steering committee for final
analysis
• Information from breakout sessions will be
used for potential future studies
Additional Considerations
• Recruit labs to participate
– Develop criteria for lab inclusion
– Number of labs needed for initial pilot study
• Amount of Funding and Mechanism of
Funding
• Develop CRADA or other enabling tools to
foster cooperation and coordination – if needed
• How and when to transition from pilot to
method validation and standardization