Transcript 'Base excision DNA repair: from basic science to human

"Base excision DNA repair:
from basic science to human disease"
DNA repair is a collection of several multienzyme, multistep processes
keeping the cellular genome intact against genotoxic insults.
One of these processes is base excision repair, which deals with the most
ubiquitous lesions in DNA: oxidative base damage, alkylation, deamination,
sites of base loss and single-strand breaks, etc.
The recent years were marked with identification of some individual repair
enzymes, understanding of their structure and many interactions that make
base excision repair a functional, versatile system.
In this lecture, selected research projects will be presented and implications
for human health and disease will be discussed.
Dr. Dmitry Zharkov
Associate Professor
Institute of Chemical Biology and Fundamental Medicine
Novosibirsk State University
Novosibirsk, Russia
Monday, Oct 25, 4 PM. SL120.
Refreshments: CB 275 at 3:45 PM