Transcript AGED-RELATED MACULAR DEGENARTION. (AMD)

AGED-RELATED MACULAR
DEGENERATION. (AMD)
BY: Basiru Lee Leigh
Mentor: Dr. Lee Angioletti
Angioletti Retina Associates
The part of the eye dealing with
AMD.
The RETINA: the Retina is a
delicate lining in the
back of the eye that
creates impulses that
travel through the optic
nerve to the brain.
The MACULA: the part of
the eye that allows you
to see fine details.
• AMD is a disease associated with aging that gradually
destroys the sharp central vision of the eye.
• AMD is also the leading cause of irreversible severe
central visual loss.
• AMD mostly Affects adults 50 years and older in the
United States.
• AMD affects the macula.
• AMD has two forms: Dry & Wet AMD.
What are the causes and symptoms
of AMD.
• CAUSES: It can be cause by variety of factors like genetic, age,
nutrition, smoking and sunlight exposure.
• SYMPTOMS:
1. Difficulty in reading.
2.distorted vision.
3. loss of central vision. This symptom mostly happens in the
Dry type.
Cures for Dry and Wet
AMD.
• Dry AMD has no treatment, but patients are told to take
vitamins and see an ophthalmologist every now and
then.
• Wet AMD:
1.laser photocoagulation therapy.
2.photodynamic therapy (PDT).
3. injection of Anti-VEGF (Lucentis, Avastin,
kenalog, etc)
• It’s when cells and blood vessels beneath
the macula break down and cause
deposits in the eye.
• In the United States about 90% of the
patients with AMD have the Dry type.
• It causes only 10% vision loss in the
patients with Dry AMD.
• Wet AMD happen when abnormal blood
vessel growth forms beneath the Macula.
• Only 10% of the patients with AMD have
the Wet type in the Untied States.
• It also causes 90% of the vision loss in the
patients.
OBJECTIVE
• To see if vitamins can reduce the risk of
severe vision loss.
• To combine two treatments for Wet AMD
and see the results.
MATERIALS
1.
DRY AMD.
.Took pictures of their eyes.
. They were told to take vitamins containing Zinc (80mg), copper (2mg), vitamins
A,C and E. And to see the ophthalmologist on regular bases.
2.
WET AMD.
. Took pictures of the eye.
. Dilate the eyes.
. Then injected with Lucentis or Kenlog, followed up by PDT,
or some times PDT by itself.
.There eyes are later washed with an iodine solution.
. Patients were told to come back every three months for more
injection if the eye get worst.
PATIENT’S TREATMENT
• This patients AMD wasn’t that severe so
the patients was told to take small
amounts of vitamins.
• The patients also had to come to see the
Doctor every six months.
PATIENTS TREATMENT.
• The patient with the Wet AMD was severe and it
was untreated for a while, the patient could
have gone legally blind if the eye wasn’t
treated, although the OD (Rigth eye) couldn’t
see.
• The patient was injected with Lucentis (0.5mg)
and giving PDT.
• He was released and told to come back in three
month.
Expected Results
• Dry AMD:
Hope that the dry type doesn't
develop into a wet type, or to lose most
of his/her vision.
Wet Type:
We expected the Kenalog plus the
PDT would lessen the amount swelling
and coagulate abnormal blood vessels.
REFERENCES
http://www.gene.com/gene/news//press- releases/display.do?method=detail&id=9147
http://www.nei.nih.gov/health/maculardegen/armd-facts.asp#1a
http://www.macular-degenation.org/
Veteporfin in photodynamic therapy study group: by AM J> Ophthamol
Hardy RA (2004). Retina. In D Vaughan et al., eds., General Ophthalmology, 16th ed., pp. 189–211.
New York: Lange Medical Books/McGraw-Hill.
http://www.stlukeseye.com/conditions/maculardegeration.asp.
http://www.amd.org
http://alconlabs.com/us/eo/conditions/AMD/causesAMD.jhtml
Acknowledgements
• Dr. Lee Angioletti
• Dr. sat
• Harlem children society
• MSKCC