Transcript Folie 1

The Swiss Chemical and
Pharmaceutical Industry
Zurich, April 2015
1
Chemicals in Consumer Products
100.0
90.0
80.0
70.0
60.0
50.0
40.0
30.0
20.0
10.0
-
Source: ACC, CEFIC
2
World-wide sales
"top ten" Swiss chemical and pharmaceutical companies
Total 2014: 143.6 bn CHF
Europe
46.8 bn CHF
33%
Switzerland
2.3 bn CHF
2%
Source: scienceindustries 2015
3
Asia, Africa,
Australia
32.2 bn CHF
22%
America
62.2 bn CHF
43%
Leading Chemical Export Nations 2013
billion EUR
180,000
160,000
140,000
120,000
100,000
80,000
60,000
40,000
20,000
Turkey
Australia
South Africa
Argentinia
Czech Republic
Hungary
Indonesia
Denmark
Brazil
Israel
Mexiko
Malaysia
Poland
Austria
Sweden
Taipei, Chinese
Thailand
Russian…
Canada
Saudi Arabia
India
Spain
Singapore
Italy
Republic of Korea
Ireland
Japan
United Kingdom
Switzerland
France
the Netherlands
China
Belgium
4
United States
Source: VCI 2015
Germany
0
Focus on life science and chemical specialties
World-wide sales of the "top ten" Swiss companies
Total 2014: 143.6 bn CHF
Crop protection
14.0 bn CHF
10%
Diagnostics
10.8 bn CHF
8%
Vitamins, flavours and
fragrances
9.0 bn CHF
6%
Pharmaceuticals
91.2 bn CHF
63%
Source: scienceindustries 2015
5
Fine and specialty
chemicals
18.7 bn CHF
13%
Increasing trend towards pharmaceuticals
Share of the specialties in the total exported volume
100%
Other Specialties
Flavors / Fragrances
90%
Crop Protection
Colours
80%
Organic Products
70%
Pharmaceuticals
60%
50%
40%
30%
20%
10%
0%
1980
1990
Source: scienceindustries 2015
6
2000
2002
2004
2006
2008
2010
2012
2014
Export Growth of Sectors 1980 - 2014
1980 = 100 %
Pharmaceuticals
(1,878.0 %)
Crop Protection
(423.9 %)
Flavors / Fragrances
(391.3 %)
Other Specialties
(349.1 %)
Organic Products
(204.4 %)
Pharmaceuticals / Vitamines and Crop
Protection Products:
until 1988 excluding intermediates
Colours
(107.5 %)
Source: scienceindustries 2015
7
Organic Products:
until 1988 including intermediates
Increased focus of the companies
Industry restructuring illustrated by the Basle based chemical companies (1970 – 2010)
8
Worldwide Presence
World map of direct investments
Source: scienceindustries 2012
9
Employees abroad
Employees of the "top ten" companies by region
Total 2014: 322’900 employees
Europe
101,300
31%
Switzerland
45,000
14%
Source: scienceindustries 2015
10
Americas
92,800
29%
Asia, Africa,
Australia
83,800
26%
Growing importance of direct investments abroad
Development of headcount of the "top ten" companies by region
120,000
1997
2014
100,000
80,000
60,000
40,000
20,000
Switzerland
Source: scienceindustries 2015
11
Europe
America
Asia, Africa,
Australia
High research intensity
International comparison of research intensity (Pharma R&D / turnover) in 2011
90.00
80.00
70.00
60.00
50.00
40.00
30.00
20.00
10.00
Switzerland
Source: IFPMA/EFPIA 2013
12
Japan
USA
EU 27
Internationally integrated research
R & D expenditures
Total 2014: 20.7 bn CHF
16.00
abroad
Switzerland
14.00
12.00
10.00
8.00
6.00
4.00
2.00
2003 2004 2005 2006 2007 2008 2009 2010 2012 2014
Source: scienceindustries 2015
13
Rapidly rising cost of R & D
R & D cost for an new pharmaceutical molecule (NCBE)
in Mio. US $
1,600
1,400
1,200
1,000
800
600
400
200
0
1979
Source: EFPIA 2013
14
1987
1991
1993
2003
2012
Patent protection
The market introduction of a pharmaceutical takes time and money
start patent protection
development
research
screening
clinical
SPoC*
2 - 4 years
chances of success
market
preclinical
selection
end patent protection
20 years
phase I II III
IV
authorization
introduction
4 - 7 years
%
12%
%
67%
%
100%
1.5
1
substances
10’000 - >100’000
6-8
costs
ca. 1/3
* SPoC = Selection Proof of Concept
Source: Novartis, scienceindustries 2007
15
ca. 2/3
> 1 bn USD
R&D expenditures in Switzerland
Private research expenditures
Total 2012: 12.8 bn CHF (intramuros)
Information &
Communication
798 Mio. CHF
6%
Food
1,017 Mio. CHF
8%
Others
1,528 Mio. CHF
12%
Chemicals
297 Mio. CHF
2%
Hightec
Instruments
1,214 Mio. CHF
9%
Machines
1,927 Mio. CHF
15%
Metals
333 Mio. CHF
3%
Source: economiesuisse, SFSO 2013
16
Pharmaceuticals
5,706 Mio. CHF
45%
Employees in R&D in Switzerland
Research staff in the industry
Total 2012: 47’750 employees
Others
13,105
27%
Food
351
1%
Chemicals &
pharmaceuticals
12,233
26%
Source: economiesuisse, SFSO 2013
17
Machinery,
metals
9,617
20%
Information &
communication
6,480
14%
Research labs
5,964
12%
Exports are financing R&D in Switzerland
Financing deficit of the "top ten" Swiss companies (2014)
in billion CHF
7.0
6.0
5.0
4.0
3.0
2.0
1.0
Sales
Source: scienceindustries 2015
18
R & D expenses
Strong dependency on exports
Total exports and domestic sales 2014: 89.8 bn CHF
Asia
13.1 bn CHF
15%
Other regions
3.1 bn CHF
3%
Rest of Europe
2.6 bn CHF
3%
EU
47.3 bn CHF
53%
Source: SCA, scienceindustries 2015
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Latin America
3.9 bn CHF
4%
North America
15.3 bn CHF
17%
Domestic Sales
4.5 bn CHF
5%
Important export industry
Total Swiss exports 2014: 208.3 bn CHF
Total 2012: 211.8 bn CHF
Metals &
machinery
66.2 bn CHF
32%
Textiles &
clothing
3.2 bn CHF
1%
Source: SCA 2015
20
Food,
beverages,
tobacco
8.4 bn CHF
4%
Others
23.0 bn CHF
11%
Chemicals &
pharmaceuticals
85.3 bn CHF
41%
Watches
22.3 bn CHF
11%
Export Growth in % 1998 - 2014
% numbers in brackets: share of chemicals & pharmaceuticals exports 2013
250
700
200
600
500
150
400
100
300
50
400
350
300
250
200
150
100
50
0
- 50
- 100
200
0
100
0
- 50
- 100
- 100
(58.5 %)
- 200
(18.0 %)
500
400
300
200
200
150
100
50
0
- 50
- 100
(4.6 %)
Source: scienceindustries 2015
21
(15.3 %)
100
0
- 100
- 200
(2.1 %)
350
300
250
200
150
100
50
0
- 50
- 100
- 150
(1.6 %)
Dyes & Pigments
Crop Protection
Pharmaceuticals, Vitamines, Diagnostica
Chemicals & Pharmaceuticals
Total Swiss Exports
Growing importance of exports
Share of chemicals and pharmaceuticals in total Swiss exports
%
45.0
40.0
35.0
30.0
25.0
20.0
15.0
10.0
5.0
1980
Source: scienceindustries 2015
22
1990
2000
2002
2004
2006
2008
2010
2012
2014
Significant trade surplus
International comparison of the export surplus 2013
in billion EUR
per capita in EUR
Switzerland
Belgium
Switzerland
Netherlands
Belgium
Germany
Netherlands
Germany
United Kingdom
United Kingdom
France
France
Japan
Japan
United States of America
United States of America
China
China
Spain
Spain
Italy
-60.0
-50.0
-40.0
-30.0
-20.0
-10.0
Source: VCI 2015, Worldbank 2015
23
Italy
0.0
10.0
20.0
30.0
40.0
50.0
-1,800-1,400-1,000 -600 -200 200
600 1,000 1,400 1,800 2,200 2,600 3,000 3,400 3,800 4,200
Contribution to Gross Domestic Product
selected industries 1998 – 2012
%
6.00
1998
2000
2002
5.00
2004
2006
2008
4.00
2010
2012p
3.00
2.00
1.00
Food
Source: SFSO 2015
24
Watches
Chemicals &
pharmaceuticals
Metals & machinery
Dynamic industry
Development of production index (1995 - 2011)
% (1995 = 100)
200.0
150.0
100.0
50.0
-
Total
Textiles
Food
Energy, water
Electrical engineering
Paper and printing
Engineering
25
Metals
Source: SFSO 2013
Chemicals & pharmaceuticals
-50.0
Dynamic Pharmaceutical Industry
Development of production index (1995 - 2014)
(% 2004 = 100)
240.0
220.0
200.0
180.0
Total
Oils & Chemicals
160.0
Pharmaceuticals
Electrical engineering
140.0
Engineering
120.0
100.0
80.0
2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014
Source: SFSO 2014
26
Major employer in industry
Employees by industry sector in %
Total of industry: 622’836 (2014)
Electrical
equipment
5.4 %
Engineering
12.6 %
Others
19.2 %
Data Processing
Equipment &
Watches
16.9 %
Food & Tabaco
9.7 %
Metals
15.1 %
Pharmaceuticals
6.4 %
Source: SFSO 2015
27
Mineral Oil &
Chemicals
4.5 %
Wood, Paper &
Printing
10.3 %
Size of the Swiss chemical and phamaceutical companies
Distribution of employment by company size (2012)
500.00
450.00
400.00
350.00
300.00
Chemicals
250.00
Pharmaceuticals
200.00
150.00
100.00
50.00
<10
Source: SFSO 2015
28
10 bis <50
50 bis <250
250 und mehr
Size of the Swiss companies
Distribution of employment by company size (2008)
0 to 9 employees
(452 enterprises)
1,774
10 to 49
employees (212
enterprises)
5,810
50 to 249
employees (120
enterprises)
14,145
more than 249
employees (50
enterprises)
49,045
Source: SFSO 2013
29
Responsible Care
Number of workplace accidents per mio. working hours (LTIR)
14.0
12.0
10.0
8.0
6.0
4.0
2.0
1993
1996
Source: scienceindustries 2013
30
2000
2001
2002
2003
2004
2005
2006
2007
Responsible Care
Energy consumption in terajoules per production unit
120.0
100.0
80.0
60.0
40.0
20.0
0.0
2002
Source: scienceindustries 2013
31
2003
2004
2005
2006
2007
Responsible Care
CO2 emissions in tons per production unit
9,000
8,000
7,000
6,000
5,000
4,000
3,000
2,000
1,000
0
1993 1996 2000 2002 2004 2006 2007 2008 2009 2010
Source: scienceindustries 2013
32
Responsible Care
VOC emissions
4,000
3,500
3,000
2,500
2,000
1,500
1,000
500
0
1993 1996 2000 2002 2004 2006 2007 2008 2009 2010
Source: scienceindustries 2013
33
Responsible Care
Water consumption
350
Cooling water
Process water
300
250
200
150
100
50
0
1996
2000
Source: scienceindustries 2013
34
2001
2002
2003
2004
2005
2006
2007