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STIs in Victoria who why prevention Rebecca Guy Centre for Epidemiology and Population Health Research, The Macfarlane Burnet Institute for Medical Research and Public Health Why are STIs important? • Common • Morbidity • Asymptomatic • Often missed • Associated with systemic disease • Facilitation of HIV transmission Chlamydia Rising chlamydia diagnoses, Australia 60000 50000 number 40000 30000 20000 10000 0 07 20 06 20 05 20 04 20 03 20 02 20 01 20 00 20 99 98 97 96 95 94 93 92 91 Year Who is affected by chlamydia? • Most infections among heterosexuals • High rates among MSM • High rates among Indigenous Australians 1. Sexual Health (2005) 2:185-192 Interpreting chlamydia trends • As chlamydia is often asymptomatic nature, notification data underestimate chlamydia prevalence • Testing is increasing each year Correlation between chlamydia notifications and testing 1999-2005 Notifications per 100,000 230 210 190 170 150 130 110 90 70 50 500 750 1000 1250 Tests per 100,000 1500 1750 Chlamydia Prevalence in Australia • ~4% of sexually active 18 to 24 year old women1 Victorian community survey • ~4% of heterosexually active 16 to 29 year old men2 • ~5% in gay men • ~ 10%-15% in Indigenous Australian populations 1. 2. Hocking et al. ISSTDR, November 2005 ANZJPH (2007) 31(3):243-6 Youth: chlamydia risk factors • Younger age • Increased number of partners • Recent partner change Youth: knowledge & behaviours • Big Day Out (BDO) Study • A survey of over 900 young people at the 2007 Melbourne BDO music festival • 35% had multiple sexual partner/s in the past year • 40% had new sexual partner/s in the past three months • Of those with new sexual partners, 53% always used condoms in the past year • Of those with casual partners, 53% used condoms all the time. • Secondary school kids, year 10,12 (2002) – Poor levels of knowledge Chlamydia Control issues • No screening = many undetected infections • Short of a vaccine – screening is the key to control • Chlamydia is a good candidate for screening – Its complications are important health problems – It is easily diagnosed – simple urine test for men and women – It is detectable early – It is easily and effectively treated – single dose treatments (1g azithromycin) – Early treatment reduces the risk of complications Screening is cost-effective • Review of published cost-effectiveness studies found that screening was cost-effective at prevalence rates of 3.1% and over1 • Department of Health and Ageing announced $12.5 million for increased chlamydia awareness, improved surveillance and a pilot testing program. 1. STI (2002) 78:406-412 Australian screening program • Screening likely to be based in primary health care – ~90% of young women and 70% of young men attend a GP each year – Only 6-8% of 16-24 yr old women get tested • Questions to be addressed – What resources/skills do GPs need to increase chlamydia screening – Who should be screened? • ?Age group – likely to be <25 years • Should men be screened? – How often should people be screened? – What coverage should we aim for? STI awareness Campaign • • • • Victorian government 14 June 2007 Aimed at 18 to 25 year olds Radio, posters “You never know who you’ll meet” • Raise awareness of STIs & increase safe sex behaviours, regular STI check ups Syphilis Infectious syphilis notifications, Victoria, 2000 to 2007 Number of notifications 450 400 80% MSM 350 300 250 4 18 200 150 234 100 50 0 117 84 9 16 28 55 2000 2001 2002 2003 2004 2005 2006 2007 Year Source: http://www.health.vic.gov.au/ideas/surveillance Syphilis risk factors, MSM • • • • • • • HIV positive (around 50%, Sydney1, Melb) More sexual partners1 More frequent unprotected anal intercourse More frequent unprotected oral sex2 Recreational drug use1,2 Use of sex on premises venues1,2 Meeting sexual partners through the Internet3 1 Holt M, Jin F, Grulich A et al. Syphilis, STIs men who have sex with men in Sydney, Understanding and managing risk. National Centre in HIV Social Research, 2003 2 J Epidemiol Community Health (2002) 56(3):235-236 3 JAMA (2000) 284(4):447-449 Syphilis testing, MSM • Annually testing recommended SYP – Quarterly in high risk men Number of tests 950 900 850 800 750 700 4 00 /2 11 04 0 /2 09 04 0 /2 07 04 0 /2 05 04 0 /2 03 04 0 /2 01 03 0 /2 11 03 0 /2 09 03 0 /2 07 03 0 /2 05 03 0 /2 03 03 0 /2 01 02 0 /2 11 02 0 /2 09 02 0 /2 07 • The number of syphilis tests conducted per individuals is increasing1 • The proportion of MSM tested for syphilis is not increasing2 – Approx 60% (2004, 2005, 2006) Linear (SYP) 1000 Month 1. 2. Allen K, Guy R, Leslie D, Goller J, Medland N, Roth N, Lewis J, Hellard M. The rise of infectious syphilis in Victoria and the impact of enhanced clinical testing. Aust N Z J Public Health. 2008;32:39-42 Hull P, Prestage G, Zablotska I, et al. Melbourne Gay Community Periodic Survey 2006: National Centre in HIV Social Research, University of New South Wales; 2006. Source: Goller J, Guy R, Leslie D, Lewis J, Batrouney C, Fairley C, Ginge S, Hellard M. Evaluation of a HIV and STI testing campaign targeting men who have sex with men in Victoria 2004. 18th Annual Conference of the Australasian Society for HIV Medicine, Melbourne, Australia, October 2006. [oral] Syphilis campaigns • PLHA inc – 2008 – Syphilis health promotion – Encourage gay men to be tested HIV HIV diagnoses, Victoria 1999-2007 300 Number of new HIV diagnoses 250 200 150 242 100 187 203 211 205 206 2001 2002 2003 2004 263 256 2006 2007 132 50 0 1999 2000 2005 Year Source: http://www.health.vic.gov.au/ideas/surveillance HIV diagnosis rates, Victoria NSW and QLD Diagnosis rate per 100 000 8 7 6 5 4 3 2 1 0 1996 1997 1998 NSW 1999 2000 2001 2002 Year QLD 2003 2004 2005 VIC 2006 Unprotected anal sex with casual partners, MSM 40 Percentage 35 30 25 20 15 1998 1999 2000 NSW 2001 2002 Year QLD 2003 2004 2005 2006 VIC Source: NSW, VIC and QLD Periodic surveys, 1998-2006, men aged 30-49 Note: the sample includes only men who had sex with casual partners HIV campaigns 1. Testing campaign – To increase testing 2. UAIC campaign – To increase condom use 3. High case load clinics supported 4. New clinical services provided at convenient locations – run by MSHC Summary • Chlamydia – youth – increased testing – prevalence still high • All STIs - gay men – changes in sexual behaviour • Campaigns underway Acknowledgements • Judy Gold – Centre for Epidemiology and Population Health Research, Burnet Institute • Dr Jane Hocking – NHMRC Postdoctoral Research Fellow School of Population Health