Transcript ART use in selected PEPFAR countries (Rational Pharmaceutical Management Plus) ppt, 2.21Mb

ART Use in Selected
PEPFAR Countries
Forecasting for ARVs to 2010
November 7-8, 2005
Rational Pharmaceutical Management Plus
Source of Information
Country
Date of Data Collection
Population
Cote d'Ivoire
Sept 2005
Adults
Ethiopia
July 2005
Adults
Haiti
December ‘04 to July 2005
Adults and Pediatrics
Kenya
Sept 2005
Adults and Pediatrics
Namibia
March 2005
Adults and Pediatrics
Rwanda
August 2005
Adults and Pediatrics
Zambia
August 2005
Adults and Pediatrics
Limitations
• Data Collected from selected countries may not be
representative of total population treated in countries and
may include non-PEPFAR supported patients
• Data not available on rate of switch from 1st- to 2nd-line
regimens
• All reported regimens included in analysis of 1st-line ARV
distribution
• All regimens, except for WHO 1st-line regimens, considered in
analysis of 2nd-line ARV distribution
• Ritonavir was excluded in analysis
• Some pediatric regimens may have been counted as adults
• Pediatric regimens not organized by formulation taken-data
not available
Summary of Data Collected
• Total number of patients: 77,378
– Adult patients: 71,550
– Pediatric patients: 5,828
• Total number of adult regimens: 76
• Total number of pediatric regimens: 31
Percentage of Adult Patients on WHO 1st-line Regimens
99%
100%
95%
96%
94%
98%
99%
95.31%
90%
80%
70%
60%
50%
40%
39%
30%
20%
10%
To
ta
l
bia
Za
m
Rw
an
da
a
ibi
N
am
Ke
ny
a
ait
i
H
a
Et
hio
pi
Co
te
d'I
v
oi
re
0%
Percentage of Pediatric Patients on WHO 1st-line Regimens
98%
100%
92%
98%
98%
95.26%
Rwanda
Zambia
Total
90%
80%
69%
70%
60%
50%
40%
30%
20%
10%
0%
Haiti
Kenya
Namibia
Percentage of Adult ART Regimens with NRTIs only
4.50%
3.98%
4.00%
3.50%
3.00%
2.50%
2.00%
1.50%
1.00%
0.52%
0.50%
0.50%
0.03%
0%
0.27%
0.17%
0%
C
ot
e
l
To
ta
bia
Za
m
an
da
Rw
ibi
a
am
N
Ke
ny
a
ai t
i
H
hio
pia
Et
d'
Ivo
i re
0.00%
Percentage of Pediatric ART Regimens with NRTIs only
20.00%
18.48%
18.00%
16.00%
14.00%
12.00%
10.00%
8.00%
6.00%
4.00%
2.36%
2.00%
0.64%
0.19%
0%
0.94%
al
To
t
bia
Za
m
da
an
Rw
ibi
a
N
am
ya
Ke
n
Ha
it
i
0.00%
Distribution of ARVs in 1st-line Regimens
ARV
% in Adult Regimens
% in Pediatric Regimens
3TC
97.8%
98.7%
D4T
71.5%
43.8%
ZDV
27.7%
55.7%
TDF
0.29%
—
EFV
26.3%
27.1%
NVP
70.6%
69%
ddI
2.4%
0.84%
ABC
0.71%
1.37%
PIs
2.61%
2.99%
LPV/r
0.85%
2.95%
NFV
0.69%
0.02%
IDV
1.06%
0.02%
SQV/r
0.01%
—
Distribution of ARVs in 2nd-line Regimens
ARV
% in Adult 2nd-line
Regimens
% in Pediatric 2nd-line
Regimens
ddI
51.2%
17.8%
ABC
15%
29%
TDF
6.26%
—
PIs
55.7%
63%
IDV
22.52%
0.36%
LPV/r
18.17%
62.32%
NFV
14.69%
0.36%
SQV/r
0.15%
—
(ZDV, D4T, 3TC, EFV and NVP have been excluded)
Closing the gap between
what is known about public health problems
and what is done
to solve them