Transcript 4-Dimensional Treatment Planning of Lung Tumors

4-Dimensional Treatment
Planning of Lung Tumors
Lung Cancer
• 1 out of 14 people will be diagnosed with lung
cancer at some point in their life!
• 90% of lung cancer is caused by SMOKING.
5 years after diagnosis, only 16% survive!
Treatment Options
• Surgery
• Chemotherapy
• Radiation Therapy
–Photons
–Protons
Photons v. Protons
More distal lung is irradiated
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Chen, Mori, Sharp
Original
Deformed dose
WIP Brown Bag March 3, 2009
Room view
Organ view
Accumulated dose
Voxel view
LungEUD1 Analysis
GTY Chen
Ashley Rubenstein et al
September 28, 2010
EUD1 Fovia
Ant Field GIF no distal margin
Post Field GIF
Observations
• With post field, there is range perturbation
distal to target during motion
• More normal lung is irradiated
• Distal lung density is altered; so deeper
geometric penetration.
• Therefore EUD could change in 4D planning vs
3D planning. Magnitude depend on degree of
motion and compensator design.
EUD2 Analysis
GTYC / AER
September 28, 2010
LPO single field dose Gif
Post Obliques 2F plan GIF
EUD3 Analysis
Sept 28 2010
Single field dose distribution
Single field dose distribution
Single field dose distribution
Plan
• 4 field plan
• Quite robust to motion!
• Use more fields in proton lung!