Transcript COLLEGE OF MEDICINE SPEAKER’S FORUM

COLLEGE OF MEDICINE
SPEAKER’S FORUM
Physiologic and Genetic
Determinants of Occupational Lung Dysfunction
– Experience in the Swine Industry
Friday, November 25, 2005, 12:00-1:00 RUH Mall Lecture Theatre
Abstract:
Dr. James Dosman
Director
Institute of Agricultural
Rural and Environmental
Health (I.ARE.H)
College of Medicine
U of S
Jim Dosman was the
first Fergusson Professor of
Respiratory Diseases, and is
a past Distinguished
Scholar of CIHR.
Contacts for further information:
Excess respiratory symptoms and reductions in lung function in
farmers and workers in swine confinement industry appear to be
both atopic and non-atopic. In some workers, dysfunction may result
early in occupational asthma. In other workers an acclimatization
process appears to take place. Exposures to dust, ammonia and
endotoxin are principle determinants of dysfunction. Mutations at the
toll-like receptor 4 may protect against exposures. Management
programs in the industry are indicated.
Jim Thornhill, 966-8119 [email protected]
Bernadine Rudichuk, 966-1417 [email protected]