Transcript Synthetic Biology Synthetic Biology What is Synthetic Biology? Discover Magazine: Scientists of the Year.

Synthetic Biology
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Synthetic Biology
What is Synthetic Biology?
Discover Magazine:
Scientists of the Year
Undergraduates in Synthetic Bio.
international Genetically
Engineered Machines
http://parts.mit.edu/registry/index.php/Main_Page
37 Teams in 2006; 57 in 2007
http://parts.mit.edu/r/parts/igem/team_list.cgi
Registry of Parts - iGEM Resource
http://parts.mit.edu/registry/index.php/Part_Types
Lego Assembly for DNA Parts
http://parts.mit.edu/registry/index.php/Assembly:Standard_assembly
What can you make in SB?
Self-organized Pattern Formation
Arsenic Detector
Davidson and MWSU Join Forces
2006 iGEM Teams
http://parts2.mit.edu/wiki/index.php/Davidson_2006
http://parts2.mit.edu/wiki/index.php/Missouri_Western_State_University_2006
Burnt Pancake Problem: 2006
Sorting stacks of burnt pancakes
DNA Pancakes: order and orientation
Davidson & Missouri Western: 2006
http://www.bio.davidson.edu/people/kahaynes/FAMU_talk/Living_computer.swf
Modeling Pancake Flipping
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R2: 2 Burnt Pancakes
8 vertices, each with degree 3
Each path taken with probability 1/27
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Pancake Graph Theory
Five Prizes in 10 Categories!
Five Prizes in 10 Categories!
MO Governor Meets MWSU
iGEMmers
Todd wears
a coat & tie!
students
Governor
Matt Blunt
Jeff Poet,
Math Prof.
Hamiltonian Path Problem: 2007
Davidson & Missouri Western: 2007
Split GFP Works!
http://www.bio.davidson.edu/Courses/Immunology/Students/spring2006/Acker/GFP_halfframe.html
Traveling Salesman Problem: 2007
SB Blends Math and Biology
HHMI Proposals Due Fall, 2007
Is SB hard or expensive?
•Hire rising sophomores
•Less than $5,000 in lab expenses
•NSF Undergraduate Biology and Math Program
•Protocols student-proof and online
•Creativity and fun encouraged
•Existing lab equipment and methods
•Math modeling improves design
•Fun iGEM competition stimulates students
How can SB fit into a curriculum?
•Seminar course to prepare
•Research or Independent Study to build
•Summer research programs
•Existing Courses: Molecular Biology, Genetics,
Cell Biology, Development, Microbiology,
Biochemistry, Engineering, Modeling, Lab Methods...
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How can we learn more?
•Attend iGEM 2007 in Boston
•Read synthetic biology papers
www.bio.davidson.edu/Courses/Synthetic/read.html
•Familiarize yourself with iGEM wiki
•Form an iGEM team on your campus
•Put Synthetic Biology in your HHMI proposal
Is GCAT participating in iGEM?
•Encouraging PUIs to join the fun
•Including iGEM in HHMI request
•Sharing protocols
•Making List-serve available
•Synthetic biology workshops possible
•Develop curriculum and resources to share
http://parts.mit.edu/igem07/index.php/Davidson_Missouri_W