Global Malaria Portfolio, 2Q 2015 Classified by therapeutic type Translational Research Development Lead Human Preclinical optimisation volunteers MMV048 UCT/TIA P218 BIOTEC ACT840 Actelion SJ733 St Jude/Eisai DDD498 Merck Serono (Dundee) CDRI 9778 Ipca Patient exploratory Access Phase IIa Patient confirmatory Phase IIb/III Under review * OZ439/PQP Tafenoquine Rectal Artesunate Sanofi GSK CIPLA/Strides/TDR OZ439/FQ Sanofi KAE609 Novartis DHA-Piperaquine Paediatric Sigma-Tau Ranbaxy ** PyronaridineArtesunate Paediatric Co-trimoxazole Bactrim Inst.
Download ReportTranscript Global Malaria Portfolio, 2Q 2015 Classified by therapeutic type Translational Research Development Lead Human Preclinical optimisation volunteers MMV048 UCT/TIA P218 BIOTEC ACT840 Actelion SJ733 St Jude/Eisai DDD498 Merck Serono (Dundee) CDRI 9778 Ipca Patient exploratory Access Phase IIa Patient confirmatory Phase IIb/III Under review * OZ439/PQP Tafenoquine Rectal Artesunate Sanofi GSK CIPLA/Strides/TDR OZ439/FQ Sanofi KAE609 Novartis DHA-Piperaquine Paediatric Sigma-Tau Ranbaxy ** PyronaridineArtesunate Paediatric Co-trimoxazole Bactrim Inst.
Global Malaria Portfolio, 2Q 2015 Classified by therapeutic type Translational Research Development Lead Human Preclinical optimisation volunteers MMV048 UCT/TIA P218 BIOTEC ACT840 Actelion SJ733 St Jude/Eisai DDD498 Merck Serono (Dundee) CDRI 9778 Ipca Patient exploratory Access Phase IIa Patient confirmatory Phase IIb/III Under review * OZ439/PQP Tafenoquine Rectal Artesunate Sanofi GSK CIPLA/Strides/TDR OZ439/FQ Sanofi KAE609 Novartis DHA-Piperaquine Paediatric Sigma-Tau Ranbaxy ** PyronaridineArtesunate Paediatric Co-trimoxazole Bactrim Inst. of Trop. Med. Shin Poong PA92 (Drexel/UW/GNF) MMV253 (AstraZeneca) DF02 Dilafor N tert butyl isoquine LSTM/Liverpool/ GSK KAF156 Novartis Artemisinin Naphthoquine ** DSM265 Artemether sublingual spray Takeda KPC ProtoPharma Ltd ArtemetherLumefantrine Novartis Arterolane/PQP 4 7 5 8 9 ACTs DSM421 UTSW/UW/Monash Molecular Mechanisms Cell Based Mechanisms Sanofi Artemisone UHKST Severe Malaria NPC1161B Mississippi Antibiotics Relapse prevention RKA182 LSTM/Liverpool No progress in 24 months AQ13 Immtech Guilin Sigma-Tau Shin Poong Sanofi/DNDi 3 4 5 6 Artesunate Mefloquine CIPLA/DNDi Included in MMV portfolio post registration SAR97276 2 Artesunate Amodiaquine Heidelberg MK4815 Merck 1 PyronaridineArtesunate Methylene Blue /AQ Jacobus Novartis DHAPiperaquine Jomaa Pharma GmbH JPC3210 ArtemetherLumefantrine Dispersible Artesunate for injection Fosmidomycin Piperaquine GSK030 GSK Phase Post IV approval Non MMV * First review or approval by WHO Prequalification, or by regulatory bodies who are ICH members or observers ** approved in India but not under review by an SRA Sulfadoxine Pyrimethamine + Amodiaquine 10 Guilin 1 Brand name: Artesun®, generics by Ajanta, Cipla, Ipca, Strides, Macleods Pharma Ltd, Mylan Laboratories 2 Brand name: Coartem® Dispersible, generics by Ajanta 3 Brand name: Artesun® 4 Brand name: Eurartesim® 5 Brand name: Pyramax® 6 Brand names: CoarsucamTM, ASAQ/Winthrop®, generics by Ajanta, Ipca, Guilin, Cipla, Strides (co-blistered) 7 Brand name: SynriamTM 8 Brand name: ARCO® 9 Brand name: ArTiMistTM 10 Brand name: SPAQ-CO