Transcript Experience of a NYC hospital with nonoccupational post-exposure prophylaxis (nPEP) Antonio Urbina1, Georgina Osorio1, Daniel Egan2, Paul Galatowitsch3, Benjamen Riggan1; Zachariah Hennessey1; Victoria Sharp Center.

Experience of a NYC hospital with nonoccupational post-exposure prophylaxis
(nPEP)
Antonio Urbina1, Georgina Osorio1, Daniel Egan2, Paul
Galatowitsch3, Benjamen Riggan1; Zachariah Hennessey1;
Victoria Sharp
Center for Comprehensive Care, St. Luke’s-Roosevelt Hospital Center, Columbia University College of
Physicians and Surgeons, New York, NY, USA1; St. Luke’s-Roosevelt Hospital Center, Columbia
University College of Physicians and Surgeons, New York, NY, USA2;
Health Clear Strategies, New York, NY, USA3
Oral Abstract TUPDC0305
XIX International AIDS Conference
Washington, DC, USA
July 24, 2012
Background/Methods
• SLR has provided nPEP
in its 2 EDs and 3
outpatient HIV clinics
(CCC)
• Retrospective chart
review of adult patients
who received nPEP from
12/2009 to 2/2012
• Demographics of patients
who undertook nPEP and
completed follow-up were
compared
Patient presents to SLRH ED or
CCC within 72 hours of
exposure to potentially HIVinfected fluid.
Baseline HIV rapid antibody
testing performed with
surveillance labs. In ED, patient
provided 4-day supply of nPEP
with follow-up appointment to
CCC outpatient HIV clinic
Patient presents for follow-up.
Provided prescription (insured)
or supply of nPEP (grant
funded) to complete 28 days of
treatment 2-, 4-, and 12-week
follow-up.
Results Table 1. Baseline characteristics of patients
Characteristic
Mean Age – yr (range)
Male - no. (%)
Race/ethnicity - no. (%)
Non-Hispanic white
Risk of HIV exposure – no. (%)
men who have sex with men
Hours from HIV exposure to
presentation – hours (range)
All Patients
(N=216)
29.5 (18-62)
180 (83%)
Patients linked to care &
completed 28-day nPEP (N=116)
30 (18-62)
92 (84%)
99 (46%)
49 (42%)
139 (64%)
25 (1-74)
74 (68%)
26 (1-74)
• 116/138 (84%) of patients referred to CCC completed 4-week f/u
• No significant differences seen for patients who completed nPEP
• One patient sero-converted after initiating nPEP 32 hours post
exposure
Conclusions
• nPEP is a chemo-prophylaxis intervention that
can prevent HIV acquisition and transmission
and provides additional opportunities for
synergistic biological and behavioral
interventions.
• A multi-disciplinary approach is necessary to
coordinate care, follow-up, and supportive
counseling leading to successful linkage to care
and completion of 28-day nPEP.
Funding: This work was supported by grants from the New
York City Department of Health and Mental Hygiene and the
New York State Department of Health AIDS Institute.