Remote homology detection Genome 541 Prof. William Stafford Noble Outline • • • • • • • Pairwise alignment algorithms Hidden Markov models Iterative profile methods Profile-profile alignment Support vector machines Network diffusion Metric space embedding.

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Transcript Remote homology detection Genome 541 Prof. William Stafford Noble Outline • • • • • • • Pairwise alignment algorithms Hidden Markov models Iterative profile methods Profile-profile alignment Support vector machines Network diffusion Metric space embedding.