Transcript Ranbaxy Laboratories Limited
Slide 1
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 2
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 3
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 4
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 5
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 6
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 7
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 8
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 9
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 10
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 11
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 12
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 13
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 14
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 15
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 16
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 17
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 18
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 19
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 20
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 21
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 22
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 23
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 24
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 25
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 2
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 3
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 4
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 5
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 6
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 7
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 8
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 9
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 10
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 11
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 12
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 13
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 14
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 15
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 16
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 17
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 18
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 19
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 20
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 21
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 22
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 23
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 24
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Slide 25
Ranbaxy Laboratories Limited
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008
Safe Harbor
Except for the historical information contained herein, statements in this presentation and the
subsequent discussions, which include words or phrases such as “will”, “aim”, “will likely result”,
“would”, “believe”,
“may”, “expect”, “will continue”, “anticipate”, “estimate”, “intend”, “plan”,
“contemplate”, “seek to”, “future”, “objective”, “goal”, “likely”, “project”, “should”, “potential”, “will
pursue” and similar expressions or variations of such expressions may constitute "forward-looking
statements". These forward-looking statements involve a number of risks, uncertainties and other
factors that could cause actual results to differ materially from those suggested by the forward-
looking statements. These risks and uncertainties include, but are not limited to our ability to
successfully implement our strategy, our growth and expansion plans, obtain regulatory
approvals, our provisioning policies, technological changes, investment and business income,
cash flow projections, our exposure to market risks as well as other risks. Ranbaxy does not
undertake any obligation to update forward-looking statements to reflect events or circumstances
after the date thereof.
Mission Statement
“ To become a Research based
International Pharmaceutical Company ”
Ranbaxy Overview
Amongst top 10 Global Generic companies (CY ’07 sales ~ $1.6 Bn, +20%)
Largest pharmaceutical Company out of India
Worldwide Presence
- Ground operations in 49 countries, products sold in > 125
- Manufacturing locations in 11 countries comprising 25 facilities
Business
- International - 80%
- Domestic
- 20%
~12000 employees globally spanning 51 nationalities
Business Model
Global Reach
• Developed Markets
North America, EU, Japan
• Emerging markets
Product Portfolio
• Generics
• Branded Generics
• Branded & OTC
India, Romania, CIS, Africa
Research & Dev.
Manufacturing
• New Chemical Entities
• Dosage Form
• Generics / NDDS*
• API* - Vertical Integration
• Complex / Niche/ FTF*
• In-house / Outsource
• The India advantage
• The India advantage
* NDDS - Novel Drug Delivery System, API – Active Pharmaceutical Ingredients, FTF – First to File
Global Presence
Global Manufacturing
API facilities in India - 6, API - 5, Fermentation - 1
Global Dosage Forms (DF) facilities - 19, India - 6, Overseas - 13
USA
Romania
Malaysia
Ireland
Active Pharmaceuticals Ingredients
(APIs)Facility, Mohali
India
China
Vietnam
+ South Africa, Japan and Brazil
Nigeria
Research & Development
Dedicated Facilities for Innovative & Generics Research
> 1400 R&D Personnel ( ~ 250 PhD’s)
8-10 NCE molecules in pipeline
4 NDDS platform technologies
~ $ 100 Mn total spend (6.4% to sales)
Collaboration in Drug
Discovery Research
(DDR)
Out-licensing
in DDR
R&D I
R&D II
R&D III
R&D IV
Out-licensing
in Novel Drug
Delivery Systems
Global Sales (2005 - 2008e)
CAGR* ~ 19%
$ Mn
~ 1900 e
2000
1607
1600
1339
1178
1200
800
400
2005
2006
2007
2008
* 3 year CAGR on like-to-like basis .i.e. excluding allied businesses divested in 2005
e - estimate
Sales by Geography (DF) – 2007
RoW
$190, +39%
Europe(EU)
$363,+41%
CIS
$90,+22%
Asia
$448,+23%
North America
$415,+6%
Global Sales ($ Mn)
Dosage Form (DF)
1506
+23%
API
101
- 12%
Total
1607
+ 20%
Highlights – Year 2007
• Buoyant base business growth in USA, + 19%
Markets
• Strong performance across EU, + 41%
• Emerging markets continue robust growth, + 32%
• 180 Day exclusivity products (FTF) for USA
Key Value
Drivers
• Specialty product flow - bio-generics, oncology, etc
• Research & Development - NCE focus
• Sales at $ 1607 Mn, + 20%
Financials
• EBIDTA* at 16.5% to sales
• PAT** at $ 147 Mn, + 28%
* Excludes impact of foreign exchange gains / losses on translation. ** and extra-ordinary items
USA
24% of global sales, base business growth (excl. FTF) +19%
Distribution coverage with all major wholesalers & and retail chains
Branded business growth + 37%
- Sotret gains market leadership ~ 51% MS
- Acquisition of BMS portfolio to further strengthen dermatology franchise
Robust product flow with assured visibility on FTF products from ’08-10
- Sumatriptan - 2008, Valacyclovir - 2009, Atorvastatin & Tamsulosin - 2010
- Atleast 1 potential FTF launch anticipated from 2008 to 2012/13
Note : Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
USA – Product Pipeline
Cumulative ANDA Filings
239 cumulative filings
98 ANDAs
Para
IV
FTF
Innovator
Market Size
$ 27 Bn
141 approvals
98 pending approvals
$ 54 Bn
18 Para IV First to File
Yr 2007 – 28 filings & 18
approvals
Year 2007Source (Market Size) : IMS
European Union
Presence in 23 of the 27 EU countries
Strong product flow in ’07 with multiple Day 1’s
Key Country Sales - 2007
Total EU Sales - 2007
400
Romania
$ 363
$ 120 Mn, + 21%
+ 41%
300
France
$ 258
$ 73 Mn, + 5%
200
Germany
$ 49 Mn, + 69%
100
UK
$ 47 Mn, + 36%
$ Mn 0
2007
2006
India
Ranked in No 2 in domestic market with a 5.04% MS(Source :ORG-IMS, QTD Nov )
Sales at $ 338 Mn, + 23 % (including CHC)
Leadership in NDDS products with 7% MS. Contribution to total
sales ~ 9%
Dedicated task forces for Specialized & Chronic therapies
Chronic share contribution at 24% (21% : IMS Cum Nov ’06)
18 brands in Top 300 of Industry, 9 in Top 100
Robust Consumer Healthcare business led by flagship brand ‘ Revital’
Source : IMS - ORG
Key Value Drivers
Emerging Market /
Developed Market Mix
Enhanced Focus on
NCE Research
180 Day Exclusivity
Products in USA
Specialty Therapeutic
Segment Presence
Market Mix
Emerging
44%
Others
13%
Others
6%
Emerging
54%
Developed
40%
Developed
43%
2005
Growth well spread across geographies
Stability & sustainability of profits
2007
180 Day Exclusivity Products (USA)
Molecule
Innovator
Market
Size
Status
Year
Simvastatin*
Merck (Zocor)
$ 0.5 Bn
Launched
2006
Pravastatin*
BMS (Pravachol)
$ 0.2 Bn
Launched
2007
Sumatriptan
GSK (Imitrex)
$ 1.0 Bn
Settled
2008
Valacyclovir
GSK (Valtrex)
$ 1.3 Bn
Settled
2009
Tamsulosin
BI*/Astellas (Flomax)
$ 1.2 Bn
Settled
2010
Atorvastatin
Pfizer (Lipitor)
$ 8.0 Bn
Won ’995
2010
At-least 1 FTF launch planned each year upto 2012 / 2013
*FTF for the 80 mg dosage strength respectively. Market sizes at innovator prices (Source :IMS). BI – Boehringer Ingelheim.
Anticipated FTF launches depending on regulatory approval & litigation outcome, where applicable
Specialty Segment Presence
Leveraging front end presence & regulatory expertise
Technology & Resource intensive – high entry barriers
In-House
Alliances
• Penems
• Bio-generics
• Limuses
• Peptides
• Oral High Potency
• Oncology & Specialty
Non-cytotoxics
Injectables
Enhanced Focus on NCE Research
In-principle approval from the Board for de-merger of Drug Discovery
Research (DDR)
To create an independent pathway for DDR with dedicated resources
and enhanced focus for long term value building
Provides platform for new growth opportunities through increased
collaborations and partnerships
Specific framework & other details under finalization
NCE Pipeline
Molecule
Therapeutic Area
Status
Phase II trials (with Piperaquine)
RBx 11160
Malaria
RBx 10558
Dyslipidemia
Out-licensed to PPD Inc. 1Phase I
trials completed
RBx 9841
Urinary
Incontinence
Phase I trials completed
Candidate Selection
GSK Program - COPD / Asthma
RBx 10017876- Inhalation PDE IV B, COPD/Asthma
RBx 10020025- Tiotropium like , MRA inh, COPD/Asthma
RBx 10014255- Anti infective, Macrolide / Ketolide
RBx 10019821- Diabetes, DPP IV
have been initiated in Q4 2007
Ranbaxy – GSK Alliance
Expansion of strategic alliance established in 2003
Take leads beyond candidate selection to POC* in man
Therapeutic area focus of AI & Metabolic, Respiratory & Oncology
> $ 100 Mn in milestone and double digit royalties on
commercialization of a product
Co- marketing rights in India
First candidate identified for Respiratory Inflammation
* Proof of Concept
Financials
$ Mn
Particulars
Q4 2007
Gr.%
2007
Gr.%
2008 e
Sales
451
19%
1607
20%
+18-20 %
EBIDTA*
76
28%
~18%
% sales
Rep. PAT
17.0%
48
20%
15%
265
16.5%
191
68%
+20-25%
Adj. PAT**
45
26%
147
28%
* Excludes impact of foreign exchange gains / losses on translation
** Excludes impact of foreign exchange gains / losses on translation & extraordinary items
Summary
A vertically integrated global pharmaceutical Company
Presence across all key developed & emerging markets
Strong distribution network & brand building capabilities
India based Research & Development & Manufacturing
Robust generic product flow
New high growth specialty segments
Focus on NCE research
Thank You …
Merrill Lynch 12th India Investor Conference
New Delhi , February 2008