What Are Iridoids? • • • • • • Produced by plants as a defense against infection Found in several Chinese medicinal plants Have wide range of bioactivity Not common in fruits Not flavonoids.
Download ReportTranscript What Are Iridoids? • • • • • • Produced by plants as a defense against infection Found in several Chinese medicinal plants Have wide range of bioactivity Not common in fruits Not flavonoids.
What Are Iridoids? • • • • • • Produced by plants as a defense against infection Found in several Chinese medicinal plants Have wide range of bioactivity Not common in fruits Not flavonoids or carotenoids Heat and time stable Noni Has More Iridoids than Popular Chinese Herbs DAA content of Chinese herbs 2 1.8 mg/mL or mg/g 1.6 1.4 1.2 1 0.8 0.6 0.4 0.2 0 Noni fruit puree L. acuminatissimus Green tea Asian Ginseng Noni Has More Iridoids than Super Fruits 2.0 1.5 1.0 0.5 0.0 Note: Blueberry iridoid is not a “Noni” iridoid 0.600 Noni Has More Iridoids than Branded Super Fruit Juices 0.400 All from blueberry concentrate 0.200 Note that Kyani contains no blueberry iridoid 0.000 TNJ MonaVie Xango juice GoChi Goji juice Le' Vive juice Zrii juice G3 Kyani fruit juice Comparison of Bioactive Stability Tahitian Noni’s iridoids retain potency long after processing, pasteurization and storage. Level of major actives (µg/mL) 400 350 300 250 200 150 100 50 0 TNJ- 7 years past expiration date MovaVie Active- 1 month before expiration date Note: DAA is major bioactive in noni fruit; cyaniding 3-gluoside is major bioactive in fresh acai fruit Xango Research • One human study • Revealed no antioxidant benefit • Showed marginal anti-inflammatory benefit when 18 ounces (530 mL) was consumed per day • Orange juice provides the same antiinflammatory benefit at a lower dose (500 mL) and significantly lower cost MonaVie Research • One small human trial with 12 people • Compared MonaVie to potato flakes • Demonstrated that MonaVie produced slightly more antioxidant effects than potato flakes • Proved that MonaVie did nothing for ORAC scores in the body Product Validity Multiple human clinical studies prove Noni’s adaptogenic properties and broad range of bioactivity TNJ Human Clinical Studies 1. Safety clinical trial 2. Antioxidant- in heavy smokers 3. DNA protection- aromatic DNA adducts in heavy smokers 4. Cholesterol & triglyceride lowering- in heavy smokers 5. Joint health of the neck (cervical spondylosis) 6. Osteoarthritis of the hip & knee (not yet published TNJ Human Clinical Studies 7. Energy/Endurance 8. Immune boosting & antioxidant 9. Drug screen test 10. Hypertension trial 11. DNA protection MDA (oxidative stress related) DNA adducts in heavy smokers 12. Menopause 13. Cholesterol—non-smoker TNJ Human Clinical Studies 14. Antioxidant—non-smoker (not yet formally published) 15. Noni Leaf Serum (not TNJ, but still a TNI noni based product) TNJ Human Epidemiological Studies 16. Erysipelas and psoriasis 17. Post-market safety surveillance study 18. European epidemiological survey Do Others Compare?