Transcript Pediatrics in Review
Pediatrics in Review
Craig T. Carter, D.O.
Associate Professor Department of Emergency Medicine and Pediatrics University of Kentucky 2/2013
Some Pictures Do Not Require Captions ….
“
Ringworm
” Ringworm often causes itchy, red, scaly, slightly raised, expanding rings on the skin of the trunk of the body, face, groin or thigh fold. The ring grows outward as the infection spreads, and the center area becomes less actively infected.
Tinea…
Athlete's foot (tinea pedis). This form affects the moist areas between your toes and sometimes on your foot itself. Jock itch (tinea cruris). This form affects your genitals, inner upper thighs and buttocks. Ringworm of the scalp (tinea capitis). This form is most common in children and involves red, itchy patches on the scalp, leaving bald patches.
Q: How are kids airways different?
Anatomical airway issues in kids
big tongue, soft tissue obstruction soft trachea soft VC no cuff no stylet anterior larynx short trachea narrowest at subglottis nose breathers < 6 mos big occiput big epiglottis blade straight
Airway positioning for children <2yrs
Chalazion
Chalazion
Chalazions may be treated with any one of the following methods: 1) Antibiotics and/or steroid drops of injections; 2) Warm compresses; Warm compresses can be applied in a variety of ways, The simplest way is to hold a clean washcloth, soaked in hot water, against the closed lid for five to ten minutes, three to four times a day. Repeatedly soak the washcloth in hot water to maintain adequate heat.
3) Massage of expression of the glandular secretions; 4) Surgical incision or excision.
Pre-septal and Orbital Cellulitis
Bacterial infection usually results from local spread of adjacent URTI Preseptal usually follows periorbital trauma or dermal infection Orbital most commonly secondary to ethmoidal sinusitis Preseptal Orbital
Staphylococcus aureus
and Staphylococcus
epidermidis Streptococcus
Strep pneumoniae and pyogenes, Staph aureus Haemophilus influenzae, anaerobes
Answers when you do not know the answers…
What is this?
Superficial partial thickness burn Pink, moist,thin walled blisters Intact sensation Heal in 2-3 weeks No scarring
Burn Depth
Burn Depth
Deep partial thickness burn Red or Blanched Thick walled blisters Decreased two point discrimination Mild or exquisitely painful May heal by epithelialization 3-6 weeks High scar and contracture potential
Burn Depth
Burn Depth
Full thickness burn White, charred leathery Capillary and nerve beds destroyed Less painful/ insensate Only 1-2cm lesions can heal by contraction Grafting required High complication rates and prolonged recovery
Burn Depth
Extent of Burn
What is the Rule of Nines?
Itchy, stayed at friends house overnight, woke with pet in bed
Flea Bites
Rash
Rash w/ fever and abd pain
So what is it?
Get your clickers…
1. Meningococcemia 2. ITP/TTP 3. HUS 4. HSP 5. Petichial hemorrhages 6. RMSF
Henoch-Schonlein Purpura
Clinical Presentation Effects predominantly young children, but adults are also affected Peak incidence is 4-5 years of age There is a slight male predominance The condition is more prevalent in the winter and early spring The onset of illness is usually sudden and is preceded by a URI in at least 1/3 of cases
HSP - Clinical Presentation
Classic Triad of symptoms is the most common presentation Purpura Colicky abdominal pain arthritis 50% of children may present with symptoms other than purpura Risk of Intuss
Q: How much of their blood volume can a kid lose, and still have a NORMAL bp?
Q: How much of their blood volume can a kid lose, and still have a NORMAL bp?
40%
Lymphadenitis
Spontaneous subconjunctival haemorrhage
Painless red eye without discharge VA not affected Clear borders Masks conjunctival vessels Check BP and body for other hemorrhages No treatment (lubricants) 10-14 days to resolve If recurrent: clotting, FBC Always consider abuse…
Liver Laceration from ATV
What is it?
1. ECM 2. EM 3. Fifths disease 4. No clue 5. Erythema Nodosum
What is it?
1. ECM 2. EM 3. Fifths disease 4. No clue 5. Erythema Nodosum
Erythema Multiforme
Symmetrically distributed, erythematous, expanding macules or papules evolve into classic iris or target lesions, with bright red borders and central petechiae, vesicles, or purpura.
Lesions may coalesce and become generalized.
Vesiculobullous lesions develop within preexisting macules, papules, or wheals.
Rash favors palms and soles, dorsum of the hands, and extensor surfaces of extremities and face.
Postinflammatory hyperpigmentation or hypopigmentation may occur.
Eye involvement occurs in 10% of EM cases, mostly bilateral purulent conjunctivitis with increased lacrimation.
Mucous membrane blistering occurs in about 25% of cases of EM, is usually mild, and typically involves the oral cavity.
Varicella
Varicella
Agent: varicella zoster virus Transmission: respiratory Period of communicability: 1 day before eruption of vesicles.
Prodromal phase: slight fever, malaise, pruritic rash; macular to papular to vesicular.
Management of Varicella
Isolation Skin care: tepid bath, calamine lotion, clip finger nails.
Keep from scratching Antihistamines for itching - Benadryl No ASA – acetaminophen only.
Varicella vaccine now available.
97% immunity in 2m-12 y 78% immunity in 13y-adult 2% can have attenuated disease
Parent of the year…NOT!
What is it and what is next best test?
Seat Belt sign
1. Mumps 2. Measeles 3. Ruebella 4. Small pox 5. No clue
What is it?
Measles: Diagnosis / Clinical
Clusters of children with fever, cough, conjunctivitis, coryza, morbilliform rash
Measles: Signs and Symptoms
Peak of Illness 2-4 days after onset of rash Other signs and symptoms Anorexia, malaise, HSM Resolution Rapid improvement at end of febrile period (1 week) Complete recovery in 10-14 days Pearl: darker-skinned children Sandpaper feel to rash may be helpful
Measles or Rubeola
Agent: Virus Transmission: respiratory, blood and urine Incubation period: 10 to 20 days Period of Communicability: 4 days before and 5 days after rash appears.
Prodromal stage: fever, cough, conjunctivitis, Koplik spots.
Can get same rash/illness up to 10 d after MMR
Measles: Signs and Symptoms
Hairline Behind Ears Rash
Erythematous papular eruption
Face Trunk Limbs
Travels inferior over 2-3 days Coalesces into macular “ splotches ” Often desquamates at end of illness
Nothing here
Parent of the year…NOT
Down Syndrome
Described by John Landon Down in 1866 Etiology: nondisjuction mutation resulting in Trisomy 21 Prevalence 1:700 Most common chromosomal anomaly Associated with Maternal age > 35
Down Syndrome
Characteristics Macroglossia Micrognathia Midface hypoplasia Flat occiput Flat nasal bridge Epicanthal folds Up-slanting palpebral fissures Progressive enlargement of lips Hands: Simian crease (continuous line in the palm of the hand), short broad hands, underdevelopment of middle portion of the 5th finger resulting in the finger bending towards the outside of the hand.
Name 4 medical issues to consider in Down Syndrome patients…especially in ED!
Atlantal-axial dislocation – be wary in traumas or downs patient with neck pain or inability to ambulate Cardiovascular anomalies (40%) ASD, VSD, Tetralogy of Fallot, PDA GI anomalies (10-18%) Pyloric stenosis, duodenal atresia, TE fistula Malignancy 20 fold higher incidence of ALL Gonadal tumors
Q: What
’
s the formula for minimal systolic bp for age?
Q: What
’
s the formula for minimal systolic bp for age?
70 + (Age x 2) Eg for 5 yo: 70+5x2 = 80
MCAD ?
Group effort - Tell me everything you know (I am certain this will be a very short conversation!)
Medium chain acyl-CoA dehydrogenase deficiency (MCAD)
Fatty acid oxidation defect Disorder of ammonia detoxification Most common mitochondrial β oxidation disorder 1/10,000 5% of 313 cases SIDS Screen all infants of mothers with HELLP syndrome Results in acute toxic encephalopathy with episodes of nonketotic hypoglycemia in the 1 st 2 years of life provoked by fasting v/lethargy after fasting , usually with URI/AGE In ED: coma, hypoglycemic hypoketotic, hyperammonemia, LFTs TX: D10 Avoid fasting Carnitine 100mg/k/d
Mulluscum Contagiosum
Dictation goofs and gaffs..
“Unsure the etiology of this left upper shimmy pain.” “He had reported that he slipped and fell landing primarily with his hip on the patient's right knee. The child did not lose consciousness and did not appear to strike any other body parts. They report a car immediately afterwards” “History of present illness: Six-year-old nontender by mother mother reports intermitten…”
Febrile Seizures
CRITERIA FOR THE DIAGNOSIS OF SIMPLE FEBRILE SEIZURE
Between 6 months and 5 years of age Seizure lasting less than 15 minutes Fever present prior to the onset of the seizure
No other neurologic diagnoses
Non-focal, generalized seizure, involving all limbs
No severe metabolic disturbance No more than a single seizure per 24-hour period
No evidence of intracranial infection
Febrile SZ work-up
Clinicians evaluating infants or young children after a simple febrile seizure should direct their attention toward identifying the cause of the child's fever. In general, a simple febrile seizure does not usually require further evaluation, specifically EEGs, blood studies, or neuroimaging.
Febrile Seizures – Parental Education
The risk of febrile seizure in the general population is between ?
2% and 5%
There is no evidence that treating simple febrile seizures with anti epileptics decreases the incidence of epilepsy later in life or results in improved cognitive outcomes.
Febrile Seizures – Parental Education
If a patient is less than 12 months of age at the time of the first simple febrile seizure, the risk of second simple febrile seizure is 50%. If a patient is over 12 months of age at the time of the first simple febrile seizure, the risk of a second simple febrile seizure is 30%. Following a second simple febrile seizure, the risk of future simple febrile seizures is 50%, regardless of the age of the initial simple febrile seizure.
The risk of epilepsy is minimally increased from 1% to 2.4% in patients who have a simple febrile seizure
Mumps Clinical Features
Incubation period 14-18 days Nonspecific prodrome of low-grade fever, headache, malaise, myalgia Parotitis in 30%-40% Up to 20% of infections asymptomatic May present as lower respiratory illness, particularly in preschool-aged children
Mumps Pathogenesis
Respiratory transmission of virus Replication in nasopharynx and regional lymph nodes Viremia 12-25 days after exposure with spread to tissues Multiple tissues infected during viremia
?
Human Bites-ABUSE
Q: Name 4 things that can result in an agitated pediatric trauma patient.
Causes of agitation…
Head Injury Decreased Oxygenation Shock Altered LOC due to Alcohol, drug etc
What is this rash?
Drug Reaction/Eruption
Treatment ?
Differential Dx ? List 3…
How about now?
Coronary artery aneurysms
Hand edema – What is it?
Kawasaki Disease - Clinical Manifestations
High fever Conjunctivitis Strawberry tongue Edema of hands and feed Reddening of palms and soles Lymph node swelling
Kawasaki Disease - Clinical Tests
LFTs/TBili Albumin ESR CRP Urine CBC Thrombocytosis Leukocytosis Anemia (normocytic)
A 4yo boy presents with painful rectal bleeding. Mom describes the blood as
“
bright red, my son is going to bleed to death!
”
The most common etiology of painful rectal bleeding in this age group is?
a. Juvenile polyposis b. Anal fissure c. Crohn ’ s Disease d. Meckel ’ s diverticulum
A 4yo boy presents with painless rectal bleeding. Mom describes the blood as
“
bright red, my son is going to bleed to death!
”
The most common etiology of painless rectal bleeding in this age group is?
a. Juvenile polyposis b. Anal fissure c. Crohn ’ s Disease d. Meckel ’ s diverticulum
Dictation goofs and gaffs… What???
“I discussed this with the family and felt as though he most likely had some dry skin no switching off in this area” “She is taken to court Riche already performed chest x-ray” “Patient presents with bruising the posterior thighs which appears consistent with Niceville trauma”
Salter 1 Salter 2 Salter 3 Salter 4 Salter 5
Salter 1 Salter 2 Salter 3 Salter 4 Salter 5
Salter 1 Salter 2 Salter 3 Salter 4 Salter 5
Salter Fracture I and II
Salter Fracture III, IV and V
?
Abnormal bruising patterns ABUSE
Bowden & Greenberg Tripod position
Epiglottitis Symptoms
Acute inflammation of supra-glottic structures.
Medical Emergency Sudden onset High fever
Dysphasia and drooling
Epiglottis is cherry red and swollenDiagnosis made on presenting symptoms No tongue blade in mouth Emergency tracheostomy set No procedures until in the operating room Keep quiet
Purple Rash
Bowden & Greenberg Characteristic purpuric lesions.
Meningococcemia
Necrosis of skin
Bacterial Meningitis Pathogens
Under 2 months :E-coli, Group B streptococcus, Listeria, Haemophilus influenza type B, and Streptococcus pneumonia Beyond neonate: Strep, Haemophilus, Neisseria.
Clinical Manifestation
Severe abdominal pain Currant jelly-like stool is a classic sign.
Bowden & Greenberg
Bowden Text
Intussusception
Telescoping of part of intestine into an adjacent distal portion.
Ball & Bindler
Barium Enema
Gas filled loops of bowel
Necrotizing Enterocolitis
Necrotizing = damage and death of cells Entero = refers to intestines Colitis = inflammation of the colon60 to 80% are premature infants Feeding of concentrated formulas Infants who have received blood transfusion Infants with GI infections Infants with polycythemia: congenital heart disease
Q: List 3 trauma considerations that we often forget about, especially in children?
Q: List 3 trauma considerations that we often forget about?
1.
2.
3.
Hypothermia Child Abuse Hazardous Environments
Myelomeningocele
A protruding saclike structure containing meninges, spinal fluid and neural tissue.
Bulging anterior fontanelle Eyes deviated downward “ Setting ” Sun sign Bates: Physical Assessment
Severe Hydrocephalus
Hydrocephalus
Greek meaning water on the brain Dilation of the ventricles Two primary causes: Congenital .5 to 1% Acquired: Lesion, tumors, infection, intracranial bleed, myelomeningocele
Retinal Hemorrhages
Normal retinal Retinal hemorrhage
MRSA Burn Grp A strep Yeast No clue
What is it?
Erysipelas
Streptococcal Skin Infections
Group A Streptococci (Strep. pyogenes), which cause erysipelas, an infection affecting the superficial layers of the skin, and which classically has sharply defined borders.
Clostridium tetani
Anaerobic gram-positive, spore-forming bacteria Spores found in soil, dust, animal feces; may persist for months to years Multiple toxins produced with growth of bacteria Tetanospasmin estimated human lethal dose = 2.5 ng/kg
Tetanus Clinical Features
Incubation period; 8 days (range, 3-21 days) Three clinical forms: Local (not common), cephalic (rare), generalized (most common) Generalized tetanus: descending symptoms of trismus (lockjaw), difficulty swallowing, muscle rigidity, spasms Spasms continue for 3-4 weeks; complete recovery may take months
Pathogenesis of Lyme Borreliosis
Lyme disease characterized by three stages:
i.
Initially a unique skin lesion (
erythema chronicum migrans
(ECM)) with general malaise
ECM not seen in all infected hosts
ECM often described as Lesions
bullseye rash periodically reoccur
ii. Subsequent stage seen in 5-15% of patients with
neurological or cardiac involvement
iii. Third stage involves
migrating episodes of non destructive, but painful arthritis
Acute illness treated with phenoxymethylpenicillin or tetracycline
Diagnosis of Lyme Borreliosis
Rickettsia rickettsii -
Rocky mountain spotted fever
Q: What are the risk factors for child abuse?
Child Abuse
History story injuries history changing injury development delay seeking help inappropriate level of concern Physical Exam multiple old and new bruises posterior rib #, sternum #, spiral # < 3 yo immersion burns, cigarette
Impetigo
Impetigo contagiosa
The most common form of impetigo is impetigo contagiosa, which usually starts as a red sore on your child's face, most often around the nose and mouth. The sore ruptures quickly, oozing either fluid or pus that forms a honey-colored crust. Eventually the crust disappears, leaving a red mark that heals without scarring. The sores may be itchy
Staphylococcus aureus
Topical antibiotics. Your doctor may prescribe an antibiotic that you apply to your child's skin (topical antibiotic), such as mupirocin ointment (Bactroban). Topical antibiotics avoid side effects such as diarrhea that can result from some oral medications, but as with oral antibiotics, bacteria can become resistant to them over time. Oral antibiotics. Your doctor is likely to prescribe an oral antibiotic for ecthyma and severe cases of impetigo contagiosa. The specific antibiotic will depend on the severity of the infection and any allergies or conditions your child might have. Be sure to finish the entire course of medication even if your child seems better. This helps prevent the infection from recurring and makes antibiotic resistance less likely.
Pityriasis Rosea
It most often develops in the spring and the fall, and seems to favor adolescents and young adults. The skin rash follows a very distinctive pattern. In 3/4 of the cases, a single, isolated oval scaly patch (the "herald patch") appears on the body, particularly on the trunk, upper arms, neck, or thighs. These patches often form a pattern over the back resembling the outline of an evergreen tree with dropping branches. Patches may also appear on the neck and, rarely, on the face. These spots usually are smaller than the "herald" patch. The rash begins to heal after 2-4 weeks and is usually gone by 6-14.
Aveeno oatmeal baths, anti-itch medicated lotions and steroid creams may be prescribed to combat the rash. Lukewarm, rather than hot, baths , ERYC, Famvir
Fractures of Abuse
FIGURE 6. Multiple healing posterior rib fractures (arrows) from a compression injury of the chest.
FIGURE 7.
Metaphyseal or "bucket handle" fracture (arrow) of the tibia.
1. Parvovirus B19 2. Chilblans (cold) 3. Fifths Disease 4. Sixth disease 5. SLE butterfly rash 6. Erythema Infectiosum 7. No clue
History:
Erythema Infectiosum (Fifth Disease)
Erythema infectiosum typically has an incubation period of 4-14 days and is spread primarily via aerosolized respiratory droplets.
Transmission also occurs through blood products and from mother to fetus.
The prodromal phase often is mild enough to be noticed only rarely but may include headache, coryza, low-grade fever, pharyngitis, and malaise.
Infrequently, nausea, diarrhea, arthralgias, and abdominal pain may occur.
In hosts who are immunocompetent, the patient is viremic and capable of spreading the infection only during the incubation period.
Classic cutaneous findings follow within 3-7 days for some patients, while other patients may manifest no findings.
Erythema Infectiosum (Fifth Disease)
Physical:
Pertinent physical findings predominantly are limited to the skin and joints.
Skin (first stage): The exanthem begins with the classic slapped-cheek appearance. The bright red erythema appears abruptly over the cheeks and is marked by nasal, perioral, and periorbital sparing. The exanthem may appear like a sunburn, occasionally is edematous, and typically fades over 2-4 days.
Skin (second stage): Within 1-4 days of the malar rash, an erythematous macular to-morbilliform eruption occurs primarily on the extremities. While the eruption tends to favor the extensor surfaces, it can involve the palms and soles. Pruritus is rare.
Skin (third stage): After several days, most of the second stage eruption fades into a lacy pattern, with particular emphasis on the proximal extremities. Despite its synonym, slapped-cheek disease, the reticulate pattern is distinctly characteristic for erythema infectiosum and may be the only manifestation of the illness. The third stage lasts from 3 days to 3 weeks. After starting to fade, the exanthem may recur over several weeks following physical stimuli, such as exercise, sun exposure, friction, bathing in hot water, or stress.
Erythema Infectiosum (Fifth Disease)
Complications of PV-B19 infection include the following: Aplastic crisis: The parvovirus infects erythroid cells, causing a reticulocytopenia that lasts 7-10 days. A healthy host experiences no consequences, since the normal lifespan of a red blood cell is 120 days. In patients with a background of shortened red blood cell survival, such as hemolytic anemia, an acute aplastic crisis ensues.
Congenital infection: PV-B19 can cross the placenta during pregnancy and have a direct cytotoxic effect on fetal red blood cells. Infection
For a 24-kg child, the daily maintenance fluid requirement is approximately which of the following?
a. b. c. d. 1440cc/24hrs 1536cc /24hrs 2400cc/24hrs 1223cc/24hrs “ 4-2-1 rule ” 0-10 kg 4cc/hr x wt 11-20 kg 2cc/hr x wt >20 kg 1cc/hr x wt Easy method Anyone >20kg =wt + 40
Proper fluid bolus for a 9kg infant who presents as a severe trauma with unstable vitals is?
a. 180 cc LR x 2, then 90cc/kg pRBCs b. 180cc NSS, then 90 cc NSS c. 180 cc LR, then 180cc pRBCs d. 180cc LR x 2, then 90cc 5% albumin, then 90cc pRBCs
Scarlet fever / scarlatiniform rash
Background:
Scarlet fever is a syndrome characterized by exudative pharyngitis, fever, and scarlatiniform rash. It is caused by an infection with a pyogenic exotoxin-producing group A beta-hemolytic streptococci Infections occur year-round, but the incidence of pharyngeal disease is highest in school-aged children (5 15 y) during winter and spring and in a setting of crowding and close contact. Person-to-person spread by means of respiratory droplets is the most common mode of transmission. The incubation period for scarlet fever ranges from 12 hours to 7 days. Patients are contagious during the acute illness and during the subclinical phase.
Scarlet fever / scarlatiniform rash
The rash appears 1-2 days after onset of illness, first on the neck and then extending to the trunk and extremities. Scarlatiniform rash Exanthem texture is usually of coarse sandpaper, and the erythema blanches with pressure.
The skin can be pruritic but usually is not painful.
A few days following generalization of the rash, it becomes more intense along skin folds and produces lines of confluent petechiae known as the Pastia sign. These lines are caused by increased capillary fragility.
The rash begins to fade 3-4 days after onset, and the desquamation phase begins. This phase begins with flakes peeling from the face. Peeling from the palms and around the fingers occurs about a week later and can last up to a month.
TX Treat patients with a standard 10-day course of penicillin or erythromycin. This regimen prevents acute renal failure if antibiotics are initiated within 1 week of the onset of acute pharyngitis
Centor Criteria
1. Exudative pharyngitis 2. Fever 3. Anterior Cervical Lymphadenopathy 4. No “cold” symptoms (ie no cough or runny nose)
? (Hint – Not E.T.’s Finger)
Clubbing of Finger/Cystic fibrosis
Background: Cystic fibrosis (CF) is the most common lethal inherited disease in white persons. CF is an autosomal recessive disorder, and most carriers of the gene are asymptomatic. CF is a disease of exocrine gland function, involving multiple organ systems and chiefly resulting in chronic respiratory infections, pancreatic enzyme insufficiency, and associated complications in untreated patients. Pulmonary involvement occurs in 90% of patients surviving the neonatal period. End-stage lung disease is the principal cause of death.
Gastrointestinal tract manifestations (intestinal) Neonates: Infants may present with intestinal obstruction at birth and a variety of surgical findings, for example, meconium ileus (7-10% of patients with CF), volvulus, intestinal atresia, perforation, and meconium peritonitis. Less commonly, passage of meconium may be delayed (>24-48 h after birth) or cholestatic jaundice may be prolonged.
Infants and children: Patients present with increased frequency of stools, which suggests malabsorption (ie, fat in stools, oil drops in stools), failure to thrive, intussusception (ileocecal), or rectal prolapse.
Stevens-Johnson syndrome (SJS)
Pathophysiology: SJS is an immune-complex– mediated hypersensitivity disorder that may be caused by many drugs, viral infections, and malignancies. Cocaine recently has been added to the list of drugs capable of producing the syndrome. In up to half of cases, no specific etiology has been identified In 3-15% of cases, patients with severe SJS die
Stevens-Johnson syndrome (SJS)
The 4 etiologic categories are (1) infectious, (2) drug-induced, (3) malignancy-related, and (4) idiopathic.
Viral diseases that have been reported include herpes simplex virus (HSV), AIDS, Coxsackie viral infections, influenza, hepatitis, mumps, mycoplasmal infection, lymphogranuloma venereum (LGV), rickettsial infections, and variola. Bacterial etiologies include group A beta streptococci, diphtheria, Brucellosis, mycobacteria, Mycoplasma pneumoniae, tularemia, and typhoid. Coccidioidomycosis, dermatophytosis, and histoplasmosis are the fungal possibilities. Malaria and trichomoniasis have been reported as protozoal causes.
In children, Epstein-Barr virus and enteroviruses have been identified.
Drug etiologies include penicillins and sulfa antibiotics. Anticonvulsants including phenytoin, carbamazepine, valproic acid, lamotrigine, and barbiturates have been implicated. Mockenhapupt et al stressed that most anticonvulsant-induced SJS occurs in the first 60 days of use. In late 2002, the US Food and Drug Administration (FDA) and the manufacturer Pharmacia noted that SJS had been reported in patients taking the cyclooxygenase-2 (COX-2) inhibitor valdecoxib.
Various carcinomas and lymphomas have been associated.
SJS is idiopathic in 25-50% of cases
?
TOF
Pulmonary stenosis (a narrowing of the blood vessel to the lungs) Overriding aorta (the main blood vessel from the heart to the entire body is somewhat displaced) A ventricular septal defect (hole in the wall between the lower two chambers of the heart) Right ventricular hypertrophy (a thick muscle in the right pumping chamber)
TOF
First presentation may include poor feeding, fussiness, tachypnea, and agitation.
Emergency Department Care:
The ED physician should be able to recognize and treat a hypercyanotic episode as one of the very few pediatric cardiology emergencies that may present to the ED. Hypoxic tet spell: Hypercyanotic episodes are characterized by paroxysms of hyperpnea, prolonged crying, intense cyanosis, and decreased intensity of the murmur of pulmonic stenosis.
Mechanism - Secondary to infundibular spasm and/or decreased SVR with increased right-to-left shunting at the VSD, resulting in diminished pulmonary blood flow If left untreated, may result in syncope, seizure, stroke, or death
Treatment for the acute setting of hypercyanosis includes the following: Knee-chest position: Place the baby on the mother's shoulder with the knees tucked up underneath. This provides a calming effect, reduces systemic venous return, and increases SVR.
Oxygen is of limited value since the primary abnormality is reduced pulmonary blood flow.
Morphine sulfate, 0.1-0.2 mg/kg IM/SC, may reduce the ventilatory drive and decrease systemic venous return.
Phenylephrine, 0.02 mg/kg IV, is used to increase SVR.
Treat acidosis with sodium bicarbonate, which may reduce the respiratory center stimulating effect of acidosis.
General anesthesia is a last resort.
1.
2.
3.
4.
5.
Candida EBV CMV Diptheria No clue
?
Infectious mononucleosis
History:
IM may have a varied clinical presentation, but the symptoms usually consist of fever, pharyngitis, and lymphadenopathy.
The incubation period of IM is 4-6 weeks. Patients usually do not recall a history of possible exposure.
Prodromal symptoms consisting of 1-2 weeks of fatigue, malaise, and myalgia are common In more than 90% of cases, IM is secondary to EBV infection
Infectious mononucleosis - Labs
Liver function tests (LFTs) are abnormal in more than 90% of patients with IM.
Serum transaminase and alkaline phosphatase levels usually are modestly elevated.
The serum bilirubin may be increased in approximately 40% of patients, but jaundice only occurs in approximately 5% of IM cases.
CBC : differential that demonstrates greater than 50% lymphocytes, an absolute lymphocyte count greater than 4500, or an elevated lymphocyte count with greater than 10% atypical lymphocytes Also can have thrombocytosis Splenic rupture is a serious complication of IM, but it occurs in fewer than 0.5% of cases. More than 90% of splenic rupture cases occur in male patients.
?
The Limping Child
Slipped Capital Femoral Epiphysis
What is the red line called?
Slipped Capital Femoral Epiphysis
Klein ’ s line Superior femoral neck lateral portion femoral head Mild widening, lucency, irregularity of physis Blurring of junction metaphysis/physis (early)
Radiograph
Legg-Calvé-Perthes Disease
Avascular necrosis leading to collapse, fragmentation, and then reossification Most frequent between 4 and9 years Boys more often than girls Bilateral in 10% of cases
Management - LCP
Disease is self-limited – limp can last 2 to 4 years Nonsteroidal anti-inflammatory agents Limit activities Crutches/braces occasionally needed May help maintain spherical femoral head Better outcomes in younger children
?
Clinical Features: Your First Clue
Irritability Fever Erythema Limp/refusal to walk Decreased range of motion of limb
Septic Arthritis of ankle
Management
Once the diagnosis of septic joint is made, surgical intervention should proceed ASAP.
Needle aspiration or open surgical drainage required
Synovial Fluid Findings
Septic Arthritis Treatment by Age
Kerion
This is a vigorous inflammatory reaction to dermatophyte infection, occasionally associated with secondary bacterial infection, that occurs on the scalp, resulting in a boggy inflammatory swelling Untreated tinea capitis
Dictation Gaffs and Goofs…
“Patient is a 3-year-old male who presents after a fall from a trampoline heart about an hour and half ago” “Patient presents to emergency department on orders from right ear CBS worker” “7-year-old male female presents to emergency department with complaints of pain or right ankle. Mom prospective about 57 concrete steps last night”
Oral thrush
Signs and symptoms
Oral thrush usually produces creamy white lesions on your tongue and inner cheeks and sometimes on the roof of your mouth, gums and tonsils. The lesions, which resemble cottage cheese
Rubella/German Measles
Background: The name rubella is derived from a Latin term meaning "little red." Rubella is generally a benign communicable exanthematous disease.
The major complication of rubella is its teratogenic effects when pregnant women contract the disease, especially in the early weeks of gestation. The virus can be transmitted to the fetus through the placenta and is capable of causing serious congenital defects, abortions, and stillbirths
Rubella
Incubation period: The incubation is usually 14-21 days after exposure to a person with rubella.
Prodromal phase: Prodromal symptoms are unusual in young children but are common in adolescents and adults.
Rubella
The following signs and symptoms usually appear 1-5 days before the onset of rash: Eye pain on lateral and upward eye movement (a particularly troublesome complaint) Conjunctivitis Sore throat Headache General body aches Low-grade fever Chills Anorexia Nausea Tender lymphadenopathy
Sturge-Weber Syndrome
Sturge-Weber syndrome is a neurological disorder indicated at birth by seizures accompanied by a large port-wine stain birthmark on the forehead and upper eyelid of one side of the face.
Some children will have developmental delays and mental retardation; most will have glaucoma (increased pressure within the eye) at birth or developing later.
“ Port wine stain ”
Peds GCS/EMV - ?
1 year old, MVC, cries during exam, opens eyes spontaneously when saying Dr says name, localizes pain but not following commands 1. 15 2. 14 3. 13 4. 12 5. 11 6. 10 7. No clue
1 year old, MVC, cries during exam = 3 or 4 1. opens eyes spontaneously = 4 localizes pain but not following commands = 5 Total = 12 or 13
Eye Opening 4 Spontaneously 3 To voice 2 To pain 1 No response Verbal Response 5 Appropriate words, spontaneous cooing 4 Inappropriate words 3 Cries 2 Incomprehensible sounds, grunts 1 No response Motor Response 6 Obeys 5 Localizes pain 4 Flexion withdrawal 3 Flexion abnormal (decorticate posturing) 2 Extension (decerebrate posturing) 1 No response
Peds ICI/BHT
Found significant ICI is unlikely in a child who does not exhibit at least 1 of the high-risk criteria Evidence of significant skull fx Altered level of alertness Neuro deficit Persistent vomiting Scalp hematoma Abnl behavior coagulopathy
Headache Dizziness Depression Confusion Nausea/vomiting Sensitivity to light or noise Anxiety Poor memory Lethargy Slow response to questions Decreased energy Irritability Blurred or double vision Poor concentration Poor balance Insomnia
Severity
Grade 1 (Mild) Grade 2 (Moderate) Grade 3 (Severe)
Symptoms
No LOC, ringing, headache, dizziness, or memory loss LOC <5 min or PTA >30 min LOC >5 min or PTA >24 h
Management
Observation May not return to competition until symptom-free upon exertion Observation May not return to competition for 1 wk after symptom-free upon exertion Admit Refer for neurocognitive testing prior to resumption of contact sports LOC=loss of consciousness; PTA=posttraumatic amnesia
Eczema / Atopic Dermatitis
The most common surgical cause of vomiting in infancy is
a. Intestinal atresias b. Malrotation c. Pyloric stenosis d. Meconium ileus
Pyloric Stenosis
Pathophysiology: Marked hypertrophy and hyperplasia of the 2 (circular and longitudinal) muscular layers of the pylorus occurs, leading to narrowing of the gastric antrum.
Frequency:
In the US: The incidence of IHPS is 2-4 per 1000 live births Sex: IHPS has a male-to-female predominance of 4:1, with 30% of patients with IHPS being first-born males Age: The usual age of presentation is approximately 3 weeks of life (1-18 wk).
History:
Classically, the infant will have nonbilious vomiting or which may become projectile (up to 70%), after regurgitation, which the infant is still hungry.
Emesis may be intermittent or occur after each feeding
Branchial cleft remnants present most commonly as a(n)?
a. pain b. airway obstruction c. intraoral mass d. infection
Pediatric Cardiopulmonary Arrests
10% 10% 80% 1° Respiratory Shock 1° Cardiac
40 35 30 25 20 15 10 5 0
Age distribution of arrests
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 Age (years)
Arrive in ER in cardiac arrest (N = 80) Admit PICU (N=43) 54 % Mod Deficit (N=3) PVS at 12 mos (N=2) Died in ER (N=37) 46% Dead at 12 mos (N=1) Died in ICU (N=37) 46% Schindler M, et al. Outcome of out-of-hospital cardiac or respiratory arrest in children. N Engl J Med 1996;335:1473-1479.
List at least 10 signs of pediatric Respiratory distress
Signs of Respiratory Distress
Tachypnea Tachycardia Grunting Stridor Head bobbing Flaring Inability to lie down Agitation • • • • • • • • Retractions Access muscles Wheezing Sweating Prolonged expiration Pulsus paradoxus Apnea Cyanosis
List signs of impending respiratory failure
Impending Respiratory Failure
Reduced air entry Severe work Cyanosis despite O
2
Irregular breathing / apnea Altered Consciousness Diaphoresis
1. Bruising from abuse 2. Petechial rash 3. Mongolian spots 4. HSP 5. No clue
Specificity of Fractures for Abuse
High specificity Metaphyseal Posterior rib Scapula Spinous process Sternal Moderate specificity Multiple fractures Fractures of diff. age Epiphyseal Vertebral body Digital Complex skull Low specificity Clavicle Long bone shaft Linear skull
Radiographic Dating of Injuries
Soft tissue findings Periosteal new bone Loss of Fx line; soft callus Hard callus Remodeling Early 2-5d 4-10d 10-14d 14-21d 3 mos Peak 4-10d 10-14d 14-21d 21-42d 1 yr Late 10-21d 14-21d 42-90d 2 yr Peds Clin NA 1996
Candidiasis -Signs and symptoms
Oral thrush usually produces creamy white lesions on your tongue and inner cheeks and sometimes on the roof of your mouth, gums and tonsils. The lesions, which resemble cottage cheese Nyastatin - works by contact!
Perineal/diaper rash candidiasis antifungal cream Keep dry and open to air
Speed Round Rashes Go Interns!!
Name the rash and everything you know about it Cause Treatment Prevention
Question #1
A 1-week-old infant presents for his first newborn evaluation. He had been discharged apparently well and thriving at 48 hours of age. He now exhibits grouped vesicles on an erythematous base that were not present at birth. Wright stain of scrapings from the floor of the vesicles reveals multinucleated giant cells and balloon cells. Of the following, the MOST likely diagnosis is: A) bullous impetigo B) congenital varicella C) herpes simplex virus infection D) incontinentia pigmenti E) recessive dystrophic epidermolysis bullosa
Skin Lesions
(photos: University of California, Australian Herpes Management Forum, and eMedicine)