Transcript CS-100-Presentation-PP-2009

CS-100 (CardioStation – Model 100)
An ECG Acquisition
and
FCG (Frequency CardioGram) Diagnostic System
A Preliminary Screening Tool
To Detect Coronary Artery Diseases (CAD)
Early Ischemia to Myocardial Infarction
presentation
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Cardiovascular Disease
The #1 killer and cause of disability in the world
- 1 million deaths in the U.S. and 2.5 million worldwide every year.
- Debilitates more than 5 million very year.
Approximately 23% of myocardial infarctions go undetected.
- #1 cause of sudden death
- Irreversible debilitating condition
Over $30 billion in payments were made to Medicare beneficiaries for hospital
expenses.
CS-100 meets the need for a risk free and cost effective screening tool to
detect ischemic heart diseases in its early stage.
- Preventive screening tool for primary care physicians
- Detect ischemic condition that is reversible by exercise and dietary change
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CS-100 RESEARCH AND DEVELOPMENT
A Different Approach
- More than 30 years research and development.
- Heart is a dual functioning machine – electric generator and pump.
- Change in heart’s physiology will cause change in EKG waveform.
- Apply Digital Signal Processing Principles in digitizing and transforming 12-lead
ECG into frequency components of energy value (uV) at frequency(Hz).
- Algorithmic analysis of the ECG-derived frequency date with computer
probability assessment;
- With differential diagnosis to identify diagnostic indexes to detect ischemic
condition from early ischemia to myocardial infarction.
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Schematic Flow Chart of CS-100
Electrodes
Time Domain Cardiac
Electrical Currents
FFT (Fast Fourier
Transformation)
Into Frequency
Components
ECG
Electrocardiogram
Complied and
Recorded
Digital Signal Analysis
(1) Power Spectrum
(2) Phase Shift
(3) Impulse Response
FCG
Frequency Cardiograph
and
Diagnostic Indexes
Index Value
- Data Base
(20,000 tests)
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For the last 100 years, ECG has been detecting and diagnosing heart diseases with an
average of 50% to 55% in accuracy which means that every other test will fail. Other
non-invasive methods such as Stress ECG, Echo-Cardiogram, and Stress Echocardiogram have been used with some success to improve the diagnostic accuracy.
Test
Risk
Test
Time
ECG
None
2 min.
$75
50-55%
Low accuracy
Stress ECG
Moderate
20 min.
$300
60-80%
High false reading for
abnormal ECG
Echo-Cardiogram
None
15 min.
$200
70-75%
Limited application – valvular,
congenital, wall motion
Stress
Echo-Cardiogram
Moderate
30 min.
$400
75-80%
Higher false positive if
hypertensive
2 min.
$100
75-85%
Identify Ischemic area
FCG
None
Average
Cost/Test
Accuracy
Limitation
* The expensive and non-routinely used Ultra-Fast CT Scan & PET technology are not included for comparison.
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CS - 100
ADVANTAGES & BENEFITS
- Non-Invasive (No Injection or catheters required)
- No Strenuous Exercise Required (Patient is at rest)
- Safe and Easy to Operate
- On-site Diagnosis for CAD in 20 minutes
- High Sensitivity
- High Specificity
- Limited Training Required
- Cost Efficient
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What the Experts Say:
“This technology (cardio spectrum diagnostic system) is a signature new method
of early Screening for heart diseases. It is --- a very simple, fast, and non-invasive
method ----- and should be used in clinics where cardiac screening is performed,
as well as by primary care physicians.”
William J. Tenet, M.D., New York Hospital – Medical Center of Queens
“This technology (cardio spectrum diagnostic system) will provide a significant
new method of early diagnosis of heart diseases.”
Marne Def. Gomers, M.D., Dean of Institute of Cardiology, Foundation University of Cardiology – Brazil
“Frequency Domain FCG may index LVH with a high accuracy and the prediction of
MID is largely superior (based on F statistics) to standard time-domain ECG
parameters, either taking voltage alone or time-voltage integral into consideration.
It may thus be a new tool to help indexing the probabilistic presentation of LVH.”
Paolo Emilio Puddu, Institute of Heart and Great Vessels, Ls Sapienza University, Rome, Italy
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CS – 100 FCG Spectrum Analysis
A Unique and Valuable System
- An Innovative and scientifically proven system of high degree of sensitivity
and accuracy.
- Cardiac screening for early diagnosis and preventive warning for CAD.
- Detect ischemic myocardium injuries which may eventually lead to more
serious heart problems.
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CS-100 Important Features
- This device complies with the regulatory specifications to provide the
maximum safety to patients and operators;
- A Window based diagnostic system with an easy to operate menu;
- Two built-in cardio evaluation systems (ECG and FCG);
- Capable to acquire 10 leads ECG signal simultaneously and continuously for up
to one hundred and ten seconds to average out any artificial interference;
- Provide conventional ECG reading and print-out in two different formats
(12x1 and 6x2);
- 12 power spectra (one for each lead of the 12 leads) on one page for an instant
ischemic evaluation of the entire heart.
- Advanced evaluation for cardio condition of the left ventricular.
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FCG (Frequency Cardiogram)
An Advanced Technology
- Automatically amplify, filter and digitize the 12 lead cardio-electrical signals;
- Transform those digitized signals into 12 individual frequency domain spectra;
- Frequency range from 0 Hz to 25.6 Hz with much refine 0.2 Hz resolution
- Algorithmic analysis of ECG-derived date with computer probability assessment;
- Diagnose the stage (early or advance) of the ischemia not being detected by
the conventional ECG; and
- Locating the areas with the coronary artery disease.
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ECG (Electrocardiograph)
-
CS-100 has the ECG data acquisition capability to acquire and record a
conventional 12 lead ECG simultaneously; and
-
to display and print out the ECG graph in two different formats: 12x1 and 6x2
12x1 ECG Wave Display
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6x2 ECG Wave Display
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FCG 12-Lead Power Spectrum
- CS-100 displays and prints out a power spectrum with all 12 leads on one page;
- Each power spectrum lists five (5) ischemic diagnostic indexes
12-Lead FCG Power Spectra with Ischemic Diagnostic Indexes
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12 LEAD
POWER SPECTRUM
can detect
- Insufficient myocardial energy caused by lack of blood
supply (Early Ischemia)
- Myocardium injuries
- Ventricular hypertrophy or Ischemic Cardiomyopathy
- Myocardial Ischemia
- Myocardial compensation has set in for one or more years
- CAD and its location
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Electrical events in the frontal plane and horizontal plane of the heart
Frontal Plane Leads
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Horizontal Plane Leads
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FCG – 12-Lead multi-color CAD location Display
Diagnostic
Index Value
↑
{←
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Frontal Plane Leads
→}{←
Horizontal Plane Leads
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→}
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FCG Two Lead (II and V5) Analysis
- Apply the evaluation equations of phase shift and impulse response of the
DSP to probability analyze the ECG-derived frequency data of Lead-II and
Lead-V5.
- Display and print out a two-lead frequency graph showing two power spectra
(one for lead II and one for lead V5, one phase shift and one impulse response.
Power Spectrum
For Lead-II
→
Power Spectrum
← for Lead-V5
↑
Phase Shift of
Lead-II and V5
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↑
Impulse Response
between Lead-II and V5
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FCG Two Lead (II & V5) Analysis Can Detect
-
Poor blood flow to the heart, poor blood circulation and any change
in blood dynamics.
-
Poor or defective conduction function, unstable cardiac
electricity.
- Left bundle branch conduction block.
- CAD , coronary artery blockage, or myocardial infarction (MI).
- Unstable latent cardiac electrical activities at the beginning of
contraction.
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CS-100 Display and Print-out
A. Print Individual Page
(1) 12 lead ECG (12x1 or 6x2);
(2) 12 lead power spectra with 60 diagnostic indexes (one power spectrum
with 5 indexes for each of the 12 lead); or
(3) 2 lead (II and V5) frequency graph for power spectrum, phase angle
shift and impulse response and their respective diagnostic indexes.
B. Print All (3 pages)
(1) 12 lead ECG (12x1 or 6x2), same as A.(1);
(2) 12 lead power spectra with 60 diagnostic indexes (one power spectrum
with 5 indexes for each of the 12 lead), same as A.(2) ; and
(3) 2 lead (II & V5)frequency graph same as A.(3) plus a multi-color CAD
location picture, an diagnostic index table for all 12-lead power spectra
and 2-lead phase shift and impulse response and comments. (see next
page)
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The 3rd page of CS-100 Print-All is one page showing a two-lead frequency
graph, a CAD location picture, an index table for 12-lead power spectra plus
one for the 2-lead phase shift and impulse response, and a comments box.
2-lead
Frequency →
Graph
CAD
← Location
Picture
↑
Index Table
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↑
Comment box
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