Transcript Jeopardy - Dr. Jerry Cronin

Chapter 17 – Blood
Can’t Squeeze
Blood from a
Turnip
Foreign
Blood
Investigators
Are You My
Type?
You’re a Pint
Low
Thicker than
H2 O
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FINAL ROUND
Can’t Squeeze Blood from a Turnip:
$100 Question
There are ~280 million Hb molecules in one
RBC. A single Hb molecule carries ___
molecule(s) of O2, which means that a single
RBC carries about ___ O2 molecules.
a. 1 / 280 million
b. 8 / 2 billion
c. 2 / 1 million
d. 4 / 1 billion
ANSWER
BACK TO GAME
Can’t Squeeze Blood from a Turnip:
$100 Answer
There are ~280 million Hb molecules in one
RBC. A single Hb molecule carries ___
molecule(s) of O2, which means that a single
RBC carries about ___ O2 molecules.
a. 1 / 280 million
b. 8 / 2 billion
c. 2 / 1 million
d. 4 / 1 billion
BACK TO GAME
Can’t Squeeze Blood from a Turnip:
$200 Question
All of the following except ___ leads to a
decrease in HCT.
a. Dehydration
b. Hemorrhage
c. Problems with RBC formation
d. Anemia
ANSWER
BACK TO GAME
Can’t Squeeze Blood from a Turnip:
$200 Answer
All of the following except ___ leads to a
decrease in HCT.
a. Dehydration
b. Hemorrhage
c. Problems with RBC formation
d. Anemia
BACK TO GAME
Can’t Squeeze Blood from a Turnip:
$300 Question
Why is it important that the iron – oxygen
interaction in oxyhemoglobin is weak?
a. So that an irreversible bond forms between oxygen
and the hemoglobin is weak
b. So that oxygen may dissociate into tissues
c. Because RBCs consume some of the oxygen they
carry
d. Because carbon dioxide has a higher affinity for the
iron molecule
ANSWER
BACK TO GAME
Can’t Squeeze Blood from a Turnip:
$300 Answer
Why is it important that the iron – oxygen
interaction in oxyhemoglobin is weak?
a. So that an irreversible bond forms between oxygen
and the hemoglobin is weak
b. So that oxygen may dissociate into tissues
c. Because RBCs consume some of the oxygen they
carry
d. Because carbon dioxide has a higher affinity for the
iron molecule
BACK TO GAME
Can’t Squeeze Blood from a Turnip:
$400 Question
What accounts for males’ HCT (~46) being
higher than females’ HCT (~42)?
a. Males are larger than females.
b. Females’ RBCs are smaller than males’ RBCs.
c. Androgens stimulate RBC production.
d. Estrogens breakdown RBCs at a faster rate than
they are produced.
ANSWER
BACK TO GAME
Can’t Squeeze Blood from a Turnip:
$400 Answer
What accounts for males’ HCT (~46) being
higher than females’ HCT (~42)?
a. Males are larger than females.
b. Females’ RBCs are smaller than males’ RBCs.
c. Androgens stimulate RBC production.
d. Estrogens breakdown RBCs at a faster rate than
they are produced.
BACK TO GAME
Can’t Squeeze Blood from a Turnip:
$500 Question
Under normal conditions, what is the fate of the
globular proteins of a recycled hemoglobin
molecule?
a. They are filtered by the kidneys and eliminated in
urine.
b. They are disassembled into their component amino
acids.
c. They are stripped of their heme unit and converted
into biliverdin.
d. They are converted to bilirubin and excreted in bile.
ANSWER
BACK TO GAME
Can’t Squeeze Blood from a Turnip:
$500 Answer
Under normal conditions, what is the fate of the
globular proteins of a recycled hemoglobin
molecule?
a. They are filtered by the kidneys and eliminated in
urine.
b. They are disassembled into their component amino
acids.
c. They are stripped of their heme unit and converted
into biliverdin.
d. They are converted to bilirubin and excreted in bile.
BACK TO GAME
Foreign Blood Investigators:
$100 Question
All of the following except ___ are
characteristics of all types of WBCs.
a. They can leave capillaries by diapedesis
b. They are capable of amoeboid movement
c. They are phagocytic
d. They are attracted to specific chemical
stimuli
ANSWER
BACK TO GAME
Foreign Blood Investigators:
$100 Answer
All of the following except ___ are
characteristics of all types of WBCs.
a. They can leave capillaries by diapedesis
b. They are capable of amoeboid movement
c. They are phagocytic
d. They are attracted to specific chemical
stimuli
BACK TO GAME
Foreign Blood Investigators:
$200 Question
What is the nature of and purpose of surface
antigens on RBCs?
a. Glycoproteins in the cytoplasm / Substances that
your body recognizes as foreign
b. Receptor proteins / They aid the entry of oxygen to
RBCs
c. Peripheral proteins / They trigger an immune
response
d. Integral membrane glycoproteins or glycolipids /
Substances your immune system recognizes as
“normal”
ANSWER
BACK TO GAME
Foreign Blood Investigators:
$200 Answer
What is the nature of and purpose of surface
antigens on RBCs?
a. Glycoproteins in the cytoplasm / Substances that
your body recognizes as foreign
b. Receptor proteins / They aid the entry of oxygen to
RBCs
c. Peripheral proteins / They trigger an immune
response
d. Integral membrane glycoproteins or glycolipids /
Substances your immune system recognizes as
“normal”
BACK TO GAME
Foreign Blood Investigators:
$300 Question
Which type of WBC is found in greatest
numbers in an infected cut?
a. Monocytes
b. Neutrophils
c. B lymphocytes
d. Eosinophils
ANSWER
BACK TO GAME
Foreign Blood Investigators:
$300 Answer
Which type of WBC is found in greatest
numbers in an infected cut?
a. Monocytes
b. Neutrophils
c. B lymphocytes
d. Eosinophils
BACK TO GAME
Foreign Blood Investigators:
$400 Question
Monocytes transform into ____ in tissues,
where they ____.
a. Basophils / Exacerbate inflammation
b. Plasma cells / Synthesize and release antibodies
c. Macrophages / Are phagocytic and release
chemicals that attract neutrophils
d. Natural Killer cells / Detect and destroy abnormal
tissue cells
ANSWER
BACK TO GAME
Foreign Blood Investigators:
$400 Answer
Monocytes transform into ____ in tissues,
where they ____.
a. Basophils / Exacerbate inflammation
b. Plasma cells / Synthesize and release antibodies
c. Macrophages / Are phagocytic and release
chemicals that attract neutrophils
d. Natural Killer cells / Detect and destroy abnormal
tissue cells
BACK TO GAME
Foreign Blood Investigators:
$500 Question
Sam has an infestation of large parasitic
worms. Which of the following will happen?
a. Eosinophils will release cytotoxic enzymes from
their granules.
b. Lymphocytes will engulf the worms by
phagocytosis.
c. Basophils will release histamine.
d. All types of WBCs will be damaged by the
ANSWER
parasites, causing leukopenia.
BACK TO GAME
Foreign Blood Investigators:
$500 Answer
Sam has an infestation of large parasitic
worms. Which of the following will happen?
a. Eosinophils will release cytotoxic enzymes from
their granules.
b. Lymphocytes will engulf the worms by
phagocytosis.
c. Basophils will release histamine.
d. All types of WBCs will be damaged by the
parasites, causing leukopenia.
BACK TO GAME
Are You My Type?:
$100 Question
If Sarah has surface antigen A on her RBCs,
what blood type does she have? What type of
antibodies are in her plasma?
a. O / Anti-A and anti-B
b. B / Anti-A
c. A / Anti-B
d. AB / None
ANSWER
BACK TO GAME
Are You My Type?:
$100 Answer
If Sarah has surface antigen A on her RBCs,
what blood type does she have? What type of
antibodies are in her plasma?
a. O / Anti-A and anti-B
b. B / Anti-A
c. A / Anti-B
d. AB / None
BACK TO GAME
Are You My Type?:
$200 Question
Christopher has blood type O. What type(s)
can he receive from a donor? Why?
a. O / He has anti-A and anti B antibodies in
his plasma
b. A, B, or O / He has no surface antigens on
his RBCs
c. A or O / He has anti-B surface antigens on
his RBCs
ANSWER
d. None of the above is correct.
BACK TO GAME
Are You My Type?:
$200 Answer
Christopher has blood type O. What type(s)
can he receive from a donor? Why?
a. O / He has anti-A and anti B antibodies in
his plasma
b. A, B, or O / He has no surface antigens on
his RBCs
c. A or O / He has anti-B surface antigens on
his RBCs
d. None of the above is correct.
BACK TO GAME
Are You My Type?:
$300 Question
Why can’t a person with Type A blood safely
receive blood from a person with Type B blood?
a. Mixing blood types causes infections in the
recipient.
b. The anti-A antibodies in Type A’s plasma would
react with Type B’s donated blood.
c. Type B blood would agglutinate in the recipient’s
blood vessels and plug small vessels to vital
organs.
ANSWER
d. All of the above are correct.
BACK TO GAME
Are You My Type?:
$300 Answer
Why can’t a person with Type A blood safely
receive blood from a person with Type B blood?
a. Mixing blood types causes infections in the
recipient.
b. The anti-A antibodies in Type A’s plasma would
react with Type B’s donated blood.
c. Type B blood would agglutinate in the recipient’s
blood vessels and plug small vessels to vital
organs.
d. All of the above are correct.
BACK TO GAME
Are You My Type?:
$400 Question
Why is it unlikely that the antibodies in a Type O
donors plasma would cause a transfusion reaction in
a Type A recipient?
a. Surface antigens on RBCs are more important in
determining compatibility.
b. The plasma portion of donated blood is tiny when
compared to the volume of plasma in the recipient’s
body.
c. Plasma is not transfused in blood donations.
d. O blood doesn’t have any antibodies in it s plasma.
ANSWER
BACK TO GAME
Are You My Type?:
$400 Answer
Why is it unlikely that the antibodies in a Type O
donors plasma would cause a transfusion reaction in
a Type A recipient?
a. Surface antigens on RBCs are more important in
determining compatibility.
b. The plasma portion of donated blood is tiny when
compared to the volume of plasma in the recipient’s
body.
c. Plasma is not transfused in blood donations.
d. O blood doesn’t have any antibodies in it s plasma.
BACK TO GAME
Are You My Type?:
$500 Question
Why is cross-matching performed, though both
donor and recipient are known to be the same
blood type?
a. It reveals the presence of potential cross-reactions
with surface antigens other than A, B, and Rh.
b. It ensures that neither donor nor recipient is anemic.
c. It confirms the HIV status of the donor.
d. It ensures that the donor does not have WBCs
outside the normal range.
ANSWER
BACK TO GAME
Are You My Type?:
$500 Answer
Why is cross-matching performed, though both
donor and recipient are known to be the same
blood type?
a. It reveals the presence of potential cross-reactions
with surface antigens other than A, B, and Rh.
b. It ensures that neither donor nor recipient is anemic.
c. It confirms the HIV status of the donor.
d. It ensures that the donor does not have WBCs
outside the normal range.
BACK TO GAME
You’re a Pint Low:
$100 Question
Which of the phases of hemostasis occurs first?
a. Platelet phase
b. Vascular phase
c. Fibrinolysis phase
d. Coagulation phase
ANSWER
BACK TO GAME
You’re a Pint Low:
$100 Answer
Which of the phases of hemostasis occurs first?
a. Platelet phase
b. Vascular phase
c. Fibrinolysis phase
d. Coagulation phase
BACK TO GAME
You’re a Pint Low:
$200 Question
A deficiency of albumin in plasma
contributes to ___.
a. A decrease in the ability for blood to clot
b. A decrease in the ability to fight infection
c. A decrease in osmotic pressure and decrease in
transport of fatty acids
d. A decrease in transport of hormone binding
proteins and steroid binding proteins
ANSWER
BACK TO GAME
You’re a Pint Low:
$200 Answer
A deficiency of albumin in plasma
contributes to ___.
a. A decrease in the ability for blood to clot
b. A decrease in the ability to fight infection
c. A decrease in osmotic pressure and decrease in
transport of fatty acids
d. A decrease in transport of hormone binding
proteins and steroid binding proteins
BACK TO GAME
You’re a Pint Low:
$300 Question
Which of the following is not true of platelets?
a. They are packets of cytoplasm produced from
megakaryocytes.
b. They release chemicals important to clotting.
c. Their formation is stimulated by thrombopoietin.
d. There are about 3.5 million platelets in a
microliter of blood.
ANSWER
BACK TO GAME
You’re a Pint Low:
$300 Answer
Which of the following is not true of platelets?
a. They are packets of cytoplasm produced from
megakaryocytes.
b. They release chemicals important to clotting.
c. Their formation is stimulated by thrombopoietin.
d. There are about 3.5 million platelets in a
microliter of blood.
BACK TO GAME
You’re a Pint Low:
$400 Question
Tracey has been diagnosed with pernicious
anemia. Which of the following conditions
contributed to his illness?
a. He has a vitamin B12 deficiency.
b. He has more than the normal percentage of
RBCs.
c. He has an iron deficiency.
d. He is producing too much intrinsic factor.
ANSWER
BACK TO GAME
You’re a Pint Low:
$400 Answer
Tracey has been diagnosed with pernicious
anemia. Which of the following conditions
contributed to his illness?
a. He has a vitamin B12 deficiency.
b. He has more than the normal percentage of
RBCs.
c. He has an iron deficiency.
d. He is producing too much intrinsic factor.
BACK TO GAME
You’re a Pint Low:
$500 Question
Which condition(s) stimulate the release of EPO?
What is/are effects of EPO?
a. The presence of deoxyhemoglobin in the blood /
Decreases the rate of hemoglobin synthesis
b. Blood flow to the kidneys declines / Stimulates
increase in cell division rates of erythroblasts
c. Moving to a high altitude / Speeds up maturation of
RBCs
d. B and C are correct.
ANSWER
BACK TO GAME
You’re a Pint Low:
$500 Answer
Which condition(s) stimulate the release of EPO?
What is/are effects of EPO?
a. The presence of deoxyhemoglobin in the blood /
Decreases the rate of hemoglobin synthesis
b. Blood flow to the kidneys declines / Stimulates
increase in cell division rates of erythroblasts
c. Moving to a high altitude / Speeds up maturation of
RBCs
d. B and C are correct.
BACK TO GAME
Thicker than H2O:
$100 Question
In which organ are most plasma proteins
synthesized?
a. Spleen
b. Bone marrow
c. Kidneys
d. Liver
ANSWER
BACK TO GAME
Thicker than H2O:
$100 Answer
In which organ are most plasma proteins
synthesized?
a. Spleen
b. Bone marrow
c. Kidneys
d. Liver
BACK TO GAME
Thicker than H2O:
$200 Question
All of the following except ____ is a major
function of blood.
a. Transport of dissolved gases, nutrients and
hormones
b. Stabilization of body temperature
c. Provides storage for calcium ions
d. Defense against toxins and pathogens
ANSWER
BACK TO GAME
Thicker than H2O:
$200 Answer
All of the following except ____ is a major
function of blood.
a. Transport of dissolved gases, nutrients and
hormones
b. Stabilization of body temperature
c. Provides storage for calcium ions
d. Defense against toxins and pathogens
BACK TO GAME
Thicker than H2O:
$300 Question
Why is venipuncture a common technique
for obtaining a blood sample?
a. Blood pressure is relatively low in veins.
b. Superficial veins are easy to locate.
c. Venous walls are thinner than arterial walls.
d. All of the above are correct.
ANSWER
BACK TO GAME
Thicker than H2O:
$300 Answer
Why is venipuncture a common technique
for obtaining a blood sample?
a. Blood pressure is relatively low in veins.
b. Superficial veins are easy to locate.
c. Venous walls are thinner than arterial walls.
d. All of the above are correct.
BACK TO GAME
Thicker than H2O:
$400 Question
What is the primary difference between
plasma and interstitial fluid?
a. Plasma contains significantly more protein.
b. Interstitial fluid contains no respiratory gases.
c. The concentration of ions is significantly less in
plasma.
d. Interstitial fluid contributes very little to the
volume of ECF in the body.
ANSWER
BACK TO GAME
Thicker than H2O:
$400 Answer
What is the primary difference between
plasma and interstitial fluid?
a. Plasma contains significantly more protein.
b. Interstitial fluid contains no respiratory gases.
c. The concentration of ions is significantly less in
plasma.
d. Interstitial fluid contributes very little to the
volume of ECF in the body.
BACK TO GAME
Thicker than H2O:
$500 Question
Which characteristics of blood contribute to
its high viscosity?
a. Its temperature is slightly above body
temperature?
b. Interactions among proteins, formed elements,
and water molecules in plasma
c. Its alkalinity
d. The percentage of body weight it comprises
ANSWER
BACK TO GAME
Thicker than H2O:
$500 Answer
Which characteristics of blood contribute to
its high viscosity?
a. Its temperature is slightly above body
temperature?
b. Interactions among proteins, formed elements,
and water molecules in plasma
c. Its alkalinity
d. The percentage of body weight it comprises
BACK TO GAME
FINAL ROUND Question
What contributions from the Extrinsic and Intrinsic
Pathways help form the enzyme complex
necessary to begin the Common Pathway?
a. Factors VIII and IX from the Extrinsic pathway /
Factor VII from the Intrinsic pathway
b. Factor III from the Extrinsic pathway / Factor XII
from the Intrinsic pathway
c. Factor VII from the Extrinsic Pathway / Factors
VIII and IX from the Intrinsic
ANSWER
d. None of the above is correct.
BACK TO GAME
FINAL ROUND Answer
What contributions from the Extrinsic and Intrinsic
Pathways help form the enzyme complex
necessary to begin the Common Pathway?
a. Factors VIII and IX from the Extrinsic pathway /
Factor VII from the Intrinsic pathway
b. Factor III from the Extrinsic pathway / Factor XII
from the Intrinsic pathway
c. Factor VII from the Extrinsic Pathway / Factors
VIII and IX from the Intrinsic
d. None of the above is correct.
BACK TO GAME