Transcript NAVEH-PHARMA
NAVEH PHARMA
COMMON PROBLEMS SMART SOLUTIONS
CleanEars
JUNE 2009
CLEANEARS E
AR WAX REMOVAL SYSTEM
All in One Ear irrigation & ear wax removal CE approved
Clean Ears : The Market
Impacted
Cerumen
is a common ear problem encountered in: 26% of the general population, 57% of the elderly population (particularly among hearing aids users). Earwax accumulation can cause hearing impairment, irritation and pain .
Ear Wax Removal: Current Solutions & Problems
WASH-ONLY SOLUTIONS
Ear Irrigation performed by physicians with water and syringe is
time consuming
, associated with as much as 38%
complications
canal laceration).
(such as eardrum perforation or
DISSOLVE-ONLY SOLUTIONS
Cerumenolytic preparations Ear drop application, requires
head tilting for 5-10
sheets or cloths.
minutes, is
uncomfortable
, with occasional leak out of the ear, bad odor, soiling of bed
CleanEars
Ingredients & Mechanism of Action
CleanEars is based on physical - mechanical logic.
The active ingredient is natural squalan extracted from olive oil. Squalan has similar composition, structure and character as of ear wax but is in liquid form. When applied into the ear canal as a spray, squalan particles slam into the slow moving wax particles . As in any collision, some of the kinetic energy is transferred to the wax solid particles, enabling their transformation into liquid wax material. The Vehicle cerumen.
– Mineral oil – provides inert irrigation, flushes the dissolved Spearmint oil while providing better feeling to the patient and fresh odor of the preparation.
– warms the ear canal and catalyzes the physical process
CleanEars: Clinical Studies
In a clinical trial at ENT Department of the Bikur Holim University Hospital, Jerusalem
74 patients
Efficacy of over 82%
Another clinical trial at ENT Department of the Wolfson University Hospital, Holon
No side effects reported 19 patients (38 ears)
Complains related to earwax accumulation Treatment for one week (2 sprays per ear/x 2/day) Evaluation by ENT after 1 week
Efficacy over 74% No side effect reported
60 50 40 30 20 10 0
CleanEars - Clinical Study
Prior to Treatment After Treatment with CleanEars Obstruction Degree
Clean Ears vs. Competitors
it is certainly not another “ME TOO” product
Superior efficacy of more than 75%
with Cerumenex, Murine and placebo that was respectively observed in 29.2%, 15.4%, and 41.7%
(1) (2)
In comparison,
Innovative Double action - Wash & Dissolve No need to tilt head for 5-10 minutes during application Optimal dispersion in ear canal User friendly High safety profile Well established cerumenolytic agents Fresh odor CE approved (BE/CA01/1-05766-00001) US Patent app. No. 60/987,431