Transcript Slide 1
LUNGS AND RESPIRATORY SYSTEM Lung Physical exam: 1- Inspection 2- Palpation 3- Percussion 4-Auscultation 5- Egophony INSPECTION • Deformities or asymetry • Abnormal retraction of the interpaces • Impairment in respiratory movement • • • • Tactile Fremitus Performed by : 1- placing ulnar side of hand or palm against the patient posterior chest wall. 2 – Have the patient say ninety-nine Increased tactile fremitus =increased density of the lungs (consolidation). Decreased tactile fremitus =excess subcutaneous tissue on the chest ,air or fluid Percussion • Dull =increased density such as fluid in the lungs , or lung cavity or consolidation • Tympanic = hollow air-containing structure • Resonant = structure of air within tissue • Hyperresonant = decreased density and more air , such as in emphysema Auscultation • Crackles :short discontinuous nonmusical sounds heard mostly during inspiration • Wheezes :continuous , musical , high-pitched heard mostly during expiration. • Rhonchi:lower-pitched lung sounds • Pleural rub :Sound produced by motion pleura, heard best at end of inspiration /beginning of expiration Lung auscultation Egophony • Spoken words by the patient are increased in intensity and take on different quality during auscultation.Patient says eeee”and will heard as “aaaa”in area of consolidation and in areas of compressed lung above a pleural effusion PLEURAL EFFUSION Definition Transudate : 1- increased hydrostatic pressure 2- decreased oncotic pressure 3- CHF, Cirrhosis, Nephrosis Oxidative pleural effusion • Increased capillary permeability • Tumors, Trauma, Infection Diagnosis criteria of exudate • Ratio of pleural to serum protein >0.5 • Ratio of pleural to serum LDH >0.6 • Pleural fluid LDH >2/3 upper normal limit Para pneumonic effusion : • Pleural fluid leukocyte count >10,000/mm • Always exudates • WBC >100,000 =empyema • Empyema =pus in pleural space , positive cultures, require chest tube • • • • • Gross blood in pleural fluid: Tumor (breast ,lung cancer, lymphoma) Trauma Pulmonary infarction Aortic dissection • • • • • Low glucose in pleural fluid is associated : Empyema Rheumatoid arthritis Tumor tuberculosis • • • • • High amylase in pleural fluid is associated : Pancreatitis Renal failure Tumor Esophageal rupture • PULMONARY FUNCTION TEST • Spirometry measures the rate at which the lung changes during forced breathing • Forced vital capacity (FVC) : • Fev1 :the volume of air exhaled in the first second of the FVC • Normal FEV1/FVC ratio=>0.7 Spirometry1 Normal spirogram Obstructive defect and restrictive defect Lung Infections • Pneumonia: infection of the lung parenchyma by any microorganism. Etiology: • A- community acquired pneumonia • 1-S-Pneumonia • 2- H. influenzae B- community acquired atypical • 1- chlamydia pneumoniae • 2- Legionella pneumophila • 3- Mycoplasma pneumonia C- Hospital acquired • 1- pseudomonas aeruginosa • 2 S.Aureus • 3- Enteric organisms Signs and Symptoms • A- Typical Symptoms • 1- Fever • 2- cough • 3- pleuritic chest pain B- Atypical Symptoms • 1- Dry cough • 2-headache • 3- malaise • 4- Gastrointestinal symptoms Physical exam • 1- Dullness to percussion • 2-Rales • 3- Tactiles fremitus • 4- Egophony (E to A changes ) with stethoscope Diagnosis • A – Chest Xray • 1- upper lobe infiltrate or consolidation • 2- small cavities w/o air-fluid levels( M.tb • 3- larges cavities with air-fluid levels (staph) • 4- diffuse bilateral infiltrate (PCP, Mycoplasma) Criteria for admission • 1- Age >50 • 2-Nursing home residents • 3- underlying chronic disease • 4- change in mental status • 5- Tachypnea, tachycardia, or hypotension • 6- Pleural effusion Scenario 1 • A 19 y/o college student male c/o malaise, dry cough for the last 10 days, denied fever and pleuritic chest pain .Physical unremarkable , CXR showed diffuse bilateral infiltrate. • Scenario2 A patient comes to the ER with consolidation and pleural effusion on CXR. What is the most important test to determine admission/treatment. Scenario 3 • A 27 y/o White male brought to the ER c/o productive cough, fever and pleuritic chest pain.Physical exam elicited tachypnea and crackles on R upper lobe .What other physical finding suggestive of typical pneumonia? Obstructive Disorders 1. Chronic Obstructive pulmonary Disease: A-Chronic bronchitis :chronic expiratory airflow obstruction accompanied by chronic productive cough for 3 or more months in each of 2 successive years • Emphysema :chronic expiratory airflow obstruction accompanied by permanent enlargement of the airspace distal to the terminal bronchioles due destruction of alveolar septa. • Pathophysiology of Emphysema • Centrilobular emphysema affects the respiratory bronchioles. • Panlobular emphysema occurs in patients with alpha-1 antitrypsin deficiency. • Distal acinar emphysema is associated with spontaneous pneumothorax. • Epidemiology 1- Higher prevalence in men 2- Mortality rates are higher in whites 3- Only 15 % of smokers develop COPD • Risk Factors • Smoking • Alpha-1-antitrypsin deficiency Diagnosis /Findings Chest xray: hyperinflated lungs, flattened diaphragm. Physical exam: Barrel chest Pulmonary function tests: irreversible obstructive pattern (low FEV1) Computed tomography: loss of alveolar walls Symptoms Cough Dyspnea on exertion CO2 retention (chronic bronchitis) Weight loss (emphysema) tachypnea treatment Smoking cessation Oxygen Maintain vaccination against influenza and S.pneumoniae Beta agonist and ipratropium Steroid Asthma A chronic condition characterized by: 1- airway inflammation 2- brochoconstriction 3- hypersecretion PATHOPHYSIOLOGY • IgE mediated ,associated with histamine release from mast cells(early phase) • The late phase is associated with cytokine release TRIGGERS • Exposure to pets, dust ,smoke ,carpets • Aggravation by exercise ,hot or cold weather • Seasonal changes Signs and symptoms • Chest tightness • Wheezing • Shortness of breath • cough • • • • Differential diagnosis of wheezing Reactive airway disease Congestive heart failure Foreign body aspiration (most often in children) Asthma • • • • Physical Exam Wheezing on exhalation Decreased air entry , increased expiratory phase Decreased peak flow and FEV1 Retractions of sternocleidomastoids • Intercostal muscle use for breathing • Oxygen saturation <95% • Inability to speak full sentences asthma classification and treatment