Transcript WCHRI Clinical Research Seed Grant

WCHRI Clinical Research Seed Grant
Dr. Lorin Charlton
Tatjana Alvadj
Dory Sample
WCHRI Clinical Research Seed Grant
• Initiative designed to encourage a research
integrated hospital environment by engaging
care providers in clinical research
• Designed to encourage front line workers to
get involved in research to better patient
outcomes for children and women
WCHRI Clinical Research Seed Grant
• Sponsored by the:
– Stollery Children’s Hospital Foundation
– Royal Alexandra Hospital Foundation
– Department of Pediatrics
• Applicants must have a clear association with
the Stollery Children’s Hospital or the Lois
Hole Hospital for Women
WCHRI Clinical Research Seed Grant
• Provides up to $15,000 in funding (over 12
months)
• Projects must be either:
– rapidly clinically translatable and directly impact
patient care and outcomes for children and/or
women
– or encourage educational innovation and
research aimed at improving clinical student and
postgraduate education
Previous Round
Last fall, we funded 16 of 38 applications
(42%)
Applicant Eligibility
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Must be WCHRI member
Must hold a faculty appointment at the UofA
May submit one application to each round
Can only hold one grant per year
– Note: We want to encourage participation from
front-line staff, so involvement as collaborator is
strongly encouraged
WCHRI Clinical Research Seed Grant
Must be:
Project Relevance with WCHRI Mandate
Score
Somewhat relevant to WCHRI mandate
0
Moderately relevant to WCHRI mandate
1
Highly relevant to WCHRI mandate
2
• Relevant to WCHRI vision
• DIRECTLY related to women and/or children’s
health
• See application and guidelines for more
information
WCHRI Clinical Research Seed Grant
Application
• 2 ½ pages includes:
– Description of project
– Relevance to children/women’s health
– Clear hypothesis, objectives, methodology &
outcomes
– Knowledge translation plan
– Feasibility and impact on patient care
Cont’d
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Budget
Budget justification ( ½ page)
Summary of other funding
2- page abbreviated CV
Letters of support from collaborators MUST
be included (should clearly detail their role)
Knowledge Translation activities and
plan:
• Include a K/T plan that details the anticipated
outcomes and impact
• Include details on knowledge users, how they
will be involved in study or K/T process
• Include next steps (future grant applications,
preclinical or clinical development, impacts
on health policy)
If applicant was previously unsuccessful
in a WCHRI Seed Grant competition:
• Can resubmit in the next round and address
the reviewer comments
WCHRI Clinical Research Seed Grant
• Evaluation: Each application will be reviewed
by at least 2 reviewers
• Application feedback will be provided to the
principal investigator
In qualitative health research,
investigators want to …
• …elicit emotions and perspectives, beliefs and
values, actions and behaviours and
understand participant’ responses to health
and illness and the meanings they construct
about the experience (Morse, 2012)
Research objective(s)/research
question(s)
• What is the problem? (background, significance for the
practice and knowledge development)
• State your objective(s) and research question(s)? For
example:
– Objective: to explore/to understand the perceptions
about xy disease among newcomer families from …
countries
– Research question: What are the prevailing values and
beliefs related xy disease that shape the attitude and
behaviours of newcomer families from…?
• Define the concepts!
Methods
• Explain your research paradigm: why
qualitative research?
• Use methods based on your research
question (ethnography, grounded theory, case
study, descriptive qualitative)
Data collection
• Explain your choice of data collection
methods (interviews, focus groups,
observations, documents)
– Population under the study
– Sample size (usually small!)
– Sampling technique (usually purposeful)
– Access and recruitment
Analysis/Ethical considerations
• Describe the analysis process:
– audio recording; transcription; field notes;
software for data management; analysis method
• Rigour/trustworthiness: credibility,
transferability, dependability, conformability
(Lincoln and Guba, 1985)
• Ethics: risks related to the participants, topic,
relationship, researcher (Mayan, 2009)
Budget
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Transcription
Data management software
Gift cards for participants
Refreshments for focus groups/meetings
Friendly warnings!
• Qualitative research is energy/time
consuming for all involved!
– Qualitative designs are “emergent” rather than
fixed (Morse, 1994)
– Recruitment and data collection can be very slow
– Research is an interpretative process that takes
time
– Debriefing is important for all involved!
WCHRI Clinical Research Seed Grant
• Mistakes to avoid:
– No hypothesis identified – what is the research
question?
– Feasibility
– Unclear methodology – controls?
– Part of a larger study – not really seed funding
– Clinical translation unclear
WCHRI Clinical Research Seed Grant –
cont’d
– Details vague – need to be specific
– No letters from collaborators or only from some
– Full CV submitted – only need 2-pages
– KT plan vague
– Poor writing – get someone to proofread
So now you know…..
• You are eligible to apply
• You have a realistic, well thought out research
question, and a plan to see it through
• The research fits the WCHRI mandate
• You know what needs to be included on the
application, and what doesn’t
• You know who needs to sign it
Now what?
Make a draft of your submission
– Check that it meets the requirements; have
someone else check it too, carefully
– Identify any areas that you think need “more”
– If you need “more” get “more”
• Make sure you have enough time…..
We’re here to help
WCHRI has both internal expertise and strategic
partnerships, and may be able to help with:
– Biostatistics
– Database planning and management
– Knowledge synthesis, literature review assistance
– Feasibility determination
– Budget determination
– Study conduct
contact WCHRI at
wcgrants.ualberta.ca