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Transcript Users Safety Points
Biological
Agents
Biological Agents - definition:
A micro-organism (including
those which have been
genetically modified), a cell
culture, and a human
endoparasite which may be able
to provoke any infection, allergy
or toxicity...
Biological Agents - definition ctd.:
…classified into 4 risk groups according
to their level of risk of infection
Group 1: Unlikely to cause human
disease.
Group 2: Can cause human disease
and might be a hazard to employees
but unlikely to spread to the
community.
Group 3:
Can cause severe human disease
and presents a serious hazard to
employees and may present a risk
of spreading to the community
(usually effective prophylaxis or
treatment).
Group 4 :
Which causes severe human
disease and is a serious hazard
to employees and may present
a high risk of spreading to the
community - usually NO
effective prophylaxis or
treatment).
Put them in order of danger…
Hepatitis B virus
Fasciola Hepatica
Ebola virus
Staphylococcus aureus
E. coli 0103
Class 2
Fasciola Hepatica
Staphylococcus aureus
Class 3
Hepatitis B virus (* V D)
E. coli 0103 (* T)
Class 4
Ebola virus
Legislation
Safety, Health and Welfare at Work Act
1989.
Safety, Health and Welfare at Work
(Biological Agents) Regulations 1994.
Safety, Health and Welfare at Work
(Biological Agents) Amendment
Regulations 1998.
Reg. 3 - Employer’s Duties
avoid use
prevent exposure where risk shown
(R.A.)
reduce exposure to as low as possible
apply schedule 2
good safety & hygiene principles even
where low risk
not deliberate work (schedule 1) comply with key regs.
Reg.. 4 - Risk Assessment
The process of evaluating and
ranking the risks to health and
safety at work arising from hazards
at the workplace.
Reg.. 4 - Risk Assessment
Review
YES
Biological Agent
+Your work
?? SAFE ??
NO
Stop
/Alter
Reg.. 4 - Risk Assessment
Assess risk: nature, degree & duration of
exposure, safety measures
written
several groups: all hazardous agents
renew regularly
relevant information: classification,disease
info., potential allergic or toxigenic effects
knowledge of the disease
recommendations from H.S.A.
RA - Also consider
Means of infection
If not classified - what likely
classification (err on the higher risk
level)
Persons at risk
..Particularly “Special Risk Gps” e.g.
pregnant employees
The dose
Nature of the work
Reg.. 5 - Information/Notification
RA and relevant information to H. S. A.
where RA reveals risk to health to provide
appropriate information (RA results, # of
employees exposed, emergency plan)
inform H.S.A. of accident/incident
notification to H.S.A. of 1st time work with
class 2-3 biol. Agents, etc.
notification details.
Reg.. 6 - Protective Measures
No eating/drinking
provide suitable PPE
suitable hygiene facilities
PPE arrangements
sample procedures
Reg.. 6 - Protective Measures ctd.
work clothes separate from PPE
decont./cleaning procedures -
PPE/clothes
apply special protective measures from
RA
vaccination procedure
recommendations of Schedule 5
Reg.. 7 - Information, Training…
Provide sufficient training health risks,
precautions, hygiene, PPE., accident
procedures
other employers/employee
induction training and updating
written instructions, display notices
communication in the event of an
emerg.
Reg.. 8 - Reporting Accidents
Employee’s duty to report any
accident/incident.
Reg.. 9 - Records
Record of employee exposed to Gp. 3/4
for 10 years
for at least 40 years where potential disease
indications needed
access to personal information
access to relevant collective information
access to relevant agencies, personnel
Reg.. 10. Health Surveillance
Provide relevant health
surveillance
Reg. 10. Healthcare/Veterinary
Work
Pay particular attention to the risks of this
work
Pay particular attention to the uncertainties
of such work
UNIVERSAL PRECAUTIONS
Decontamination/dis-infection procedures
Waste procedures
Isolation facilities - Gp 3 or 4
Reg.. 11 - Labs, Animal Rooms
Determine containment measures Gp.
2, 3 or 4 for research, development,
teaching or diagnostic purposes.
Carryout work in accordance with
relevant containment level
Uncertainty - level 2 may cause disease
but not cultivating/concentrating BA
Containment level 3 or 4 when
appropriate
Schedules
1 - Indicative list of Activities
2 - Risk Reduction Measures
3 - Biohazard Sign
4 - Classification of Biological
Agents (amended by 1998 Regs).
Schedules
5 - Vaccination Practice
6 - Health Surveillance
7 - Containment measures/levels
8 - Industrial Processes
Hierarchy of Controls - Sch. 2
Eliminate - substitute - limit use of
agent;
limit number of employees exposed;
use engineering controls;
minimise release
use collective (then individual)
protective measures;
Hierarchy of Controls - Sch. 2
use hygiene measures;
use signs;
emergency plans
testing for agent
waste handling
handling procedures
Biohazard sign
BLACK ON A YELLOW BACKGROUND
PRACTICAL POINTS
Biological Safety Cabinet
Vrs
Laminar Flow Cabinet
PRACTICAL POINTS
EQUIPMENT
MAINTENANCE
(Including decontamination
procedures)
PRACTICAL POINTS
WASTE DISPOSAL
(autoclaving, secure storage)
Resources
Health & Safety Exective (UK) Material
BS 5726 (1992) - Biological Safety Cabinets
Parts 1-4
Codes of Practice
SOPs