Life Science – CREO Review & Strategy

Clean air solutions

George Rossi

Agenda – CREO Review & Strategy

• • • • • Overview Access Success! – A Case History Live Demo Updated Version - Snapshot Clean air solutions

CREO - Overview

• • • • • Conceptualized by D. Donovan and S. O’Reilly in 2006 Designed originally to marry our LCC and Clean Room Design software Includes an added energy efficiency component Calculates variables that have the greatest impact on design & energy: – – Number of people in the clean room Air change rate

Generates a specification that your customer can use immediately!

Clean air solutions

Original Concept: Marry Clean with LCC

Design Company Design Engineer Client Project Room Classifation Room Size Air change per hour Room Pressure Leakage Rate Cooling / Heating

Jacobs Eng John O Connell Pfizer - France P3 Upgrade

ISO GMP

C 10 x 12 x 3.5

25 25 Pa 5% O.O5

c

H13 HEPA Filters Dampers

S. C. U.

H13 Requirements HEPA Filter Units Mark X Supply Terminals X Room access BIBO Plantroom BIBO X Camfil Pharmaseals Roomside Camsafes Plantroom Camsafes Quantity

259 81 n/a

Filter Efficiencies Supply HEPA

H14 - EN1822

Extract HEPA

H13 - EN1822

AHU Final Filter AHU Pre Filters

F9 - CEN779-2002 F6 - CEN779 - 2002

AHU Pre Filters

G4 - CEN779 - 2002

F9 Bag Filter G4 Panel Filter F6 Bag Filter Outside air % of the air is dumped to the outside air

REQUIRED DATA

Particle larger than 0.5um

3.0 E+7 (Particle / m 3 )

8.5 E+5 (Particle/ft 3)

1E+4(Part/s) Dirty air Clean room cloths

CLEAN UP RATE

Particle/m 3 after 1 min

Particle/ft 3 after 1 min

Particle/m 3 after 10 min

Particle/ft 3 after 10 min

Particle/m 3 after 1 hour

Particle/ft 3 after 1 hour

Particle/m 3 steady state

Particle/ft 3 steady state

1.24 E+8

3.52 E+6

5.32 E+6

1.51 E+5

3.02 E+3

8.57 E+1

3.02 E+3

8.57 E+1

Particle/m 3 in room at start

Particle/ft 3 in room at start

Particles from process 3.02 E+3

8.57 E+1

3.02 E+2 1.00E+10 1.00E+09 1.00E+08 1.00E+07 1.00E+06 1.00E+05 1.00E+04 1.00E+03 1.00E+02 1.00E+01 1 10m in 20m in 30 m in 60m m

Energy Performance

Kw/h €

0.075 cent

Filter Supply HEPA Media pack 45mm 68mm 100mm Face velocity 0.45 m/s 0.45 m/s 0.45 m/s Average p.drop

?

?

?

Energy running cost per filter / per year Grade D (100,000) Areas Class A/B L.A.F. Grade C (10,000) Cleanroom Offices & other non-classified areas H14 HEPA F9 Bag Filters G4 Panel Filters

Prepared by : Don Donovan

H13 HEPA F6 Bag Filters Return Air Specification and Options ( Please feel free to Copy & Paste) Terminal Housing Roomside Camsafe Plantroom Camsafe

Click here Click here Click here

CEN 779 2002 Standard EN 1822 Standard

Click here Click here

This program is to b e used as only an aid - b la, b la

HEPA & AHU Filters

Click here

Extract HEPA F9 Bag 22 sqm 40 sqm 4.0 sqm 6.5 sqm 9.4 sqm F6 Bag 4.0 sqm 6.5 sqm 9.4 sqm G4 Panel 1.0 sqm 1.3 sqm 2.5 m/s 2.5 m/s 2.5 m/s 2.5 m/s 2.5 m/s 2.5 m/s 2.5 m/s 2.5 m/s 2.5 m/s 2.5 m/s

?

?

?

?

?

?

?

?

?

?

Clean air solutions

Clean air solutions

LCC Calculation Software

Clean air solutions 6

CREO Software – CleanRoom & Energy Optimization

7 Clean air solutions

CREO Access - Life Science Industry Page

http://www.camfilfarr.com/lifescience Webinar Manual Access Request Clean air solutions

CREO – Webinars

Click here if you are having trouble viewing this m essage.

New C lean R oom E nergy O ptimization (CREO) Design Software released globally by Camfil Farr

— Register Today for the CREO Training Webinar —

Camfil Farr, the world’s leading provider of sustainable air filters and clean air solutions has just released the new CREO (Clean Room design & Energy Optimization) manual. The CREO manual outlines the basic theories and calculations for the new software while also providing valuable historic and current information on clean room standards and guidelines commonly utilized in the Life Science & Microelectronic industries.

Another industry first — The CREO software is essentially a marriage of Camfil Farr’s well known and frequently used LCC (Life Cycle Cost) Green software along with its clean room design software. The two software programs combine to make a robust planning tool that identifies the best air filter options to optimize clean room filtration and energy consumption. Taking into account the latest international industry norms, the tool also generates complete filter and hardware specifications in a simple, easy-to-use format. The software is ideally suited for A&E companies and end users who operate clean rooms in order to optimize their air filtration needs. Access to the proprietary CREO software is possible when attendance of certified training has been completed such as this webinar in addition to access approved through a local Camfil Farr office or an authorized Camfil Farr representative.

CREO Training Webinars Offered in July. Register Today.

Please click one of the dates listed to register:

Thursday, July 26, 2012 9:00 am EST Thursday, July 26, 2012 2:00 pm EST

Provided compliments of Camfil Farr.

Clean air solutions

CREO - Worksheet Pads

Clean air solutions

Success!

Two recent Case Histories from General Aire Systems

Clean air solutions

Case History 1: Integra Life Sciences

• • • • • • • Owner: Integra Life Sciences, Plainsboro, NJ Construction Manager: Javan Engineering, Fort Washington, PA MEP Firm: Gannet Fleming, Mount Laurel, NJ Mechanical Contractor: M. Davis, Wilmington, DE Project Description: An existing ISO 8 (Class 100k) clean room facility needed to be renovated and re-certified. The owner had been familiar with CREO as introduced by General Aire. General Aire was requested to assist Gannet Fleming to optimize airflow and support their design. G. Rossi worked with the engineering manager and engineers at Gannet Fleming and verified air changes and quantity of hoods for each individual room and corridor. Resulting Sale Pre-Purchased by Owner: 65 Pharmaseal Hood Bodies and panel filters. General Aire added EC motor and fan technology to tie into the existing building management system.

Additional Products Sold: Ceiling grid, clean room light fixtures, ceiling panel, construction supervision services, start-up services Clean air solutions

Case History 2: Proctor & Gamble

• • • • • • • Owner: Proctor and Gamble: Baltimore, MD Clean Room Integrator: Nicos Group, Norwood, NJ / NICOMAC, Milano, Italy MEP Firm: Spears / Votta Associates, Baltimore, MD Project Description: P&G was upgrading an existing Q.C. lab. They wanted to have a clean room enclosed with glass panel walls. Nicos Group was selected as the clean room integrator. The guide specification from the MEP firm called for a 80% ceiling coverage for an ISO 7 (Class 10k) space. General Aire provided CREO models for two rooms showing the appropriate ceiling coverage during the submittal process. Resulting Sale: Purchase by Nicos Group: 20 Slim Line terminal HEPA filters.

Additional Products Sold: Ceiling grid, clean room light fixtures, ceiling panels, supervision and installation services.

As a result of the successful project, General Aire has been invited to be on the team for an upcoming renovation of 40,000 sq. ft. of clean space manufacturing.

Clean air solutions

CREO Demo – 5-Star Solution

Clean air solutions

CREO – Demo Highlights

• • • • – – • • • • Information section on top of page CREO manual CREO user guide Life Science HEPA spec Top two key issues (ISPE HVAC & Sustainability COP): Air change rate reduction People-generated particles Report tab – finished example Final step – generate specification for customer engineer Example 5-Star selection Clean air solutions

Clean air solutions

CREO Software Demo

CREO – Access & Feedback

• • • • • • Emphasize that this software is unique and advanced No charge for access to such a specialized service Access granted only to appropriate users Access must be approved by Segment Manager One year time limit for initial access

We want to follow up and get feedback in return for access to this special software!

Clean air solutions

Clean air solutions

V2 web-based software will be ready in May 2013

V3 Project discussion: Revit drawing generation Soft-wall ‘room within a room’ More Science with V.E. factor recovery time calculations depending on diffuser type selection.

Access management tool web based log in for non Camfil Employees Your thoughts?

Clean air solutions