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Curing the Incurable Advances in Nutritional Science To Prevent and Reverse Disease Joel Fuhrman, MD Micronutrients and Macronutrients Macronutrients contain calories They are fat, carbohydrate, protein Micronutrients do not contain calories They are vitamins, minerals, phytochemicals Dr. Fuhrman’s Health Equation • In physics a key formula is E = mc2. • In nutritional science the key formula is: H=N/C Health = Nutrients / Calories Copyright © Joel Fuhrman, M.D., 2010 U.K. Food Consumption By Calories Copyright © Joel Fuhrman, M.D., 2010 Deaths From Diseases of the Heart* United States. 1900-2003 Deaths in Thousands 900 800 700 600 500 400 300 200 100 00 90 80 70 60 50 40 30 20 10 19 00 0 Years Source: American Heart Association -- CDC/NCHS. Copyright © Joel Fuhrman, M.D., 2010 Most people in the developed nations die of diseases of dietary ignorance World-wide obesity is skyrocketing This exploding rate of overweight and obesity represents a world-wide pandemic that needs urgent attention if its potential morbidity, mortality, and economic tolls are to be avoided. Over 1 billion people world wide are overweight Copyright © Joel Fuhrman, M.D., 2010 Prevalence of Diabetes Worldwide U.S. Centers for Disease Control and Prevention: Diabetes Data & Trends http://www.cdc.gov/diabetes/statistics/prev/national/figpersons.htm Copyright © Joel Fuhrman, M.D., 2010 Body Fat Kills Copyright © Joel Fuhrman, M.D., 2010 Where is the health in health care? • 7 out of 10 deaths caused by chronic diseases • WHO predicts 36 million deaths from heart disease, stroke and cancer can be prevented in the next 10 years if improvements made in food choices • Cost of dietary-related disease in the UK alone is predicted to be over E 19 billion over next 10 years. BBC News: 'Cut chronic disease deaths' call, October 4, 2005. http://news.bbc.co.uk/2/hi/health/4307472.stm Copyright © Joel Fuhrman, M.D., 2010 Heart Disease and Cancer Processed Foods Implicated • 9-year study of 34,492 women ages 55-69: 66% increased risk of death from heart disease for those eating refined grains • 15 epidemiological studies: Directly linked diets containing refined grains and refined sweets to stomach and colon cancer • 12 breast cancer studies: Increased cancer risks associated with low-fiber diets Copyright © Joel Fuhrman, M.D., 2010 Vegetables Protect Against Heart Disease and Cancer • Greens are needed to activate NRF2, which prevents plaque adhesion • Those with the highest blood levels of lutein had the healthiest blood vessels, with no atherosclerosis. • Vegetables have the most consistent and powerful association with reduction of cancers of all types Zakkar M, et al. Activation of Nrf2 in Endothelial Cells Protects Arteries From Exhibiting a Proinflammatory State. Arteriosclerosis Thrombosis and Vascular Biology. Dwyer JH, et al. Oxygenated carotenoid lutein and progression of early atherosclerosis. Circulation 2001;103(24):2922-2927. Seow A et al. Carcinogenesis. 2002;23(12):2055-61. Steinmetz KA et al. J Am Diet Assoc 1996;96(10):1027-39. Copyright © Joel Fuhrman, M.D., 2010 Seeds and Nuts Prevent Sudden Cardiac Death • Sudden Cardiac Death almost 40 percent of all heart disease deaths • The most common cause of death in people with no known heart disease • The most proven and effective intervention to reducing risk of sudden cardiac death is the regular consumption of seeds and nuts in the diet. • 23 interventional trials dramatic reduction in all-cause mortality Mukuddem-Petersen J, Oosthuizen W, Jerling JC. A systematic review of the effects of nuts on blood lipid profiles in humans. J Nutr. 2005 Sep;135(9):2082-9. Copyright © Joel Fuhrman, M.D., 2010 Excess Protein Shortens Lifespan Promotes Cancer • Lower IGF-1 levels protect against cancer and slow aging. • Animal protein intake is the key determinant of IGF-1 levels in humans • Animal protein raises cholesterol, plant protein lowers it Fontana L, et al. Long-term effects of calorie or protein restriction on serum IGF-1 and IGFBP3 concentration in humans. Aging Cell 2008; 7(5):681-687. Copyright © Joel Fuhrman, M.D., 2010 ANDI Scores reflect micronutrient density Kale 1000 Collards 916 Spinach 886 Bok Choy 839 Romaine 462 Boston 412 Broccoli 395 Artichoke 352 Cabbage 344 Green Pep 310 Carrots 288 Asparagus 280 Strawberry 254 Cauliflower 269 Tomato 197 Cherries 197 Blueberries 155 Iceburg 132 Orange 130 Cantaloupe Apple Peach Kidney Beans Green Peas Sweet Potato Soybeans Tofu Mango Cucumber Oatmeal White Potato Brown Rice Salmon Shrimp Skim Milk Grapes Corn Avocado 120 91 88 84 84 81 74 69 61 59 55 53 49 48 46 43 40 37 36 Banana 36 Walnuts 35 Almonds 33 Chicken Breast 32 Low Fat Yogurt 31 Apple Juice 30 Eggs 29 Feta Cheese 25 Whole Wheat Bread 25 Whole Milk 23 White Pasta 22 White Bread 21 Peanut Butter 21 Swiss Cheese 18 Ground Beef 17 Potato Chips 13 Vanilla Ice Cream 6 Olive Oil 2 Cola 0.6 Copyright © Joel Fuhrman, M.D., 2010 ANDI Facts • • • • • • • • • • • • calcium, beta carotene, alpha carotene, lutein, zeaxanthin lycopene fiber folate glucosinolates iron magnesium niacin •resistant starch •selenium •sterols •vitamin B1 (thiamin) •vitamin B2 (riboflavin), •vitamin B6 • vitamin B12 •vitamin C •vitamin E • zinc •ORAC score (Oxygen Radical Absorbance Capacity) Copyright © Joel Fuhrman, M.D., 2010 Dr. Fuhrman’s Nutritarian Food Pyramid Copyright © Joel Fuhrman, M.D., 2010 Food Addiction Drives Overeating Copyright © Joel Fuhrman, M.D., 2010 Alternative to Conventional Treatment? • What if there were a way to lower cholesterol drop blood pressure and prevent heart disease that was more effective than taking medications? • What if you could actually reverse adult diabetes and without the risks and the costs of drugs? • What if you could avoid angioplasty or coronary bypass surgery and actually reverse coronary disease that has already occurred? Copyright © Joel Fuhrman, M.D., 2010 Case Study Ronnie lost 140 lbs in 12 months! I would not want anyone to go through what I have had to endure in my struggle before I learned about Dr. Fuhrman. DON'T WAIT until you have a medical tragedy happen to you! Start your new life today!!! Copyright © Joel Fuhrman, M.D., 2010 Ronnie one year later Copyright © Joel Fuhrman, M.D., 2010 Percent decrease of LDL Cholesterol Jenkins, D.J., et al., Effect of a very-high-fiber vegetable, fruit, and nut diet on serum lipids and colonic function. Metabolism, 2001. 50(4): p. 494-503. NUTRITARIAN Medications Statin Drugs Low fat vegetarian American Heart Association Atkin’s Diet High Protein Mediterranean 26% 33% 16% 6% Copyright © Joel Fuhrman, M.D., 2010 Heart disease, Hypertension and Diabetes is preventable and reversible Compelling data from nutritional studies, population surveys, and interventional studies supports the effectiveness of a healthy, plant-based diet to arrest, prevent, and reverse heart disease. My experience treating hundreds of high risk heart patients over the last 20 years, with no heart disease deaths. Breslow JL. Cardiovascular disease myths and facts. Cleve Clin J Med 1998;65(6):286-287. Ornish D, et al. Intensive lifestyle changes for reversal of coronary heart disease. JAMA 1998;280:2001-2007. Copyright © Joel Fuhrman, M.D., 2010 Nobody Need Die of Heart Attacks & Stroke Dr. Esselstyn’s experience and studies – 58 patients with advance heart disease – 17 year follow-up going on all this time without one having a heart attack Dr. Ornish’s experience and studies documenting for over 20 years that heart disease is reversible with lifestyle interventions, even in most advanced cases. Esselstyn, C.B., Jr., Resolving the Coronary Artery Disease Epidemic Through Plant-Based Nutrition. Prev Cardiol, 2001. 4(4): p. 171-177. Copyright © Joel Fuhrman, M.D., 2010 Nutritarian vs. Standard Diet Nutritarian Diet • Vegetable-based • Lots of fruit, beans, seeds, nuts • Oil used sparingly • Animal products – none or rarely • Focused on nutrientdense calories Standard Diet • Grain based • Lots of dairy and meat • Oils supply a major caloric load • Animal products 2 – 4 times a day • Focused on nutrient-poor calories Foods with strongest link to disease • Processed meats, luncheon meats, barbeque meats, red meats • Fried foods • White Foods white flour, sugar, white rice The Fountain of Youth • Plant-based diet containing high micro-nutrient containing foods - vegetables and beans, mushrooms, onions, seeds, nuts, fruit • Limit (or eliminate) unhealthy foods– including processed foods and animal products Copyright © Joel Fuhrman, M.D., 2010 “Look at it this way, at least we will be able to stick to Dr. Fuhrman’s diet !” Copyright © Joel Fuhrman, M.D., 2010