Transcript Slide 1

REFERENCES from Barry Master’s
talks
CALIBRATION
Latt, Cheung, Blout, PNAS 1965
Energy Transfer. A System with
Relatively Fixed
Donor-Acceptor Separation
Synthesize ‘bisteroid’
Attach donor and acceptor to
the hydroxyl groups
Fixed donor-acceptor separation
of 20 Å
Validate 1/ r sixth power rate
Barry R. Masters
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CALIBRATION
L. Stryer and R. P.
Haugland, PNAS 1967
Energy Transfer. A
Spectroscopic Ruler
Synthesize oligomers of
poly-L-proline N=1-12
Attach donor and acceptor
to ends of oligomers
N= 5 to 12 rigid
Fixed donor-acceptor
separation of 12-46 Å
Validate 1/ r sixth power rate
Barry R. Masters
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Failure of the Ideal Dipole Approximation (IDA)
Munoz-Losa, C. Curutchet, B. P. Krueger, L. R. Hartselll, B. Mennucci
Biophysical Journal 96, June 2009
 Ideal dipole approximation is implicit in
Förster equation; it fails when molecules
are “too close”
 IDA valid to 20 Å with free rotations of
donor and acceptor
 IDA valid to only 50 Å if molecular
motions of donor and acceptor are
restricted
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Energy Transfer in Monolayer Assemblies
•
Spectroscopy of monolayer assemblies, in: Physical Methods of
Chemistry, Editor, A. Weissberger, B. Rossiter, Chapter VII, 577-702
(1972)
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Part I. Principles and applications,
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H. Kuhn,
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Part II Experimental Procedure,
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D. Möbius, H. Bücher
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A Theory of Sensitized Luminescence in Solids
D.L. Dexter
The Journal of Chemical Physics, vol. 21, no. 5, 836 (1953)
• Förster theory of energy transfer involves allowed transitions
• Dexter theory includes energy transfer by forbidden
transitions
• Dexter theory is applicable for inorganic systems, i.e.
inorganic phosphors
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Long-range resonance energy transfer in
molecular systems
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G. D. Scholes, Annu. Rev. Phys. Chem. 54: 57-87 (2003)
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Review of Förster theory for donor-acceptor pairs
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Review of electronic coupling for singlet-singlet, triplet-triplet, pairs
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Discusses Coulombic coupling as well as electronic coupling
between molecular aggregates (excitons)
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Review of medium, weak, and strong coupling in energy transfer
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Energy transfer in complex molecular assemblies
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Responsible Conduct of Research
Professor Barry R. Masters
Visiting Scientist
Department of Biological Engineering
Massachusetts Institute of Technology
Cambridge, Massachusetts
B. R. Masters, Responsible Conduct of Research
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Resources and References
CSE’s White Paper on Promoting Integrity in Scientific Journal Publications,
2009 update
http://www.councilscienceeditors.org
Avoiding plagiarism, self-plagiarism, and other questionable writing
practices: A guide to ethical writing, Miguel Roig, Ph.D.
NIH Office of Research Integrity
http://ori.gov/education/products/plagiarism
Uniform Requirements for Manuscripts Submitted to Biomedical Journals:
Writing and Editing for Biomedical Publication (Updated October 2008)
Publication Ethics: Sponsorship, Authorship, and Accountability, International
Committee of Medical Journal Editors,
http://www.icmje.org
B. R. Masters, Responsible Conduct of
Research
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Books
• Shamoo, A.E., Resnik, D. B. Responsible Conduct of Research,
Second Edition, New York, Oxford University Press, 2009. ISBN
978-0-19-536824-6
• Emanuel E. J., Grady, C., Crouch, R. A., Lie, R.K., Miller, F. G.,
Wendler, D. (Eds.)The Oxford Textbook of Clinical Research Ethics,
New York, Oxford University Press, 2009. ISBN 978-0-19-516865-5
• Beauchamp T. L., Childress, J. F. Principles of Biomedical Ethics, Fifth
Edition, New York, Oxford University Press, 2001 ISBN 0-19514332-9
• Steinbock, B. (Ed.) The Oxford Handbook of Bioethics, New York,
Oxford University Press, 2007.
ISBN: 978-0-19-927335-5
B. R. Masters, Responsible Conduct of
Research
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Books
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Scientific Style and Format, The CSE Manual for Authors, Editors, and
Publishers. 7th ed. Council of Science Editors, Reston (VA): The Council and The
Rockefeller Press, 2006
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Coghill, AM, Garson, LR, eds. The ACS Style Guide, Effective Communication of
Scientific Information, 3rd ed. New York, Oxford University Press, 2006
Part 1. Scientific Communications: Ethics in Scientific
Communication, Peer Review, Copyright Basics

AMA Manual of Style, A Guide for Authors and Editors, 10th ed. New York,
Oxford University Press , 2007
Ethical and Legal Considerations: Authorship Responsibility,
Acknowledgements, Conflicts of Interest, Financial Disclosures,
Duplicate Publication, Scientific Misconduct, Conflicts of Interest,
Intellectual Property, Ownership, Access, Rights and Management,
Confidentiality. Protecting Research Participants'’ and Patients’ Rights
in Scientific Publication
B. R. Masters, Responsible Conduct of
Research
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Books
• The Chicago Manual of Style, the Essential Guide for Writers, Editors, and
Publishers, 15th ed. Chicago, the University of Chicago Press, 2003
– Chapter 4, Rights and Permissions: Copyright Law and the Licensing of Rights, Author’s
Responsibilities, Publisher’s Responsibilities
• Publication Manual of the American Psychological Association,
5th ed. Washington, DC, American Psychological Association, 2001
– Chapter 2, Expressing Ideas and Reducing Bias in Language
–

Appendix C: Ethical Standards for the Reporting and Publishing of Scientific Information
MLA Style Manual and Guide to Scholarly Publishing, 2nd ed. Gibaldi J,
New York, The Modern Language Association of America, 1998

Chapter 2, Legal Issues in Scholarly Publishing (A. F. Abelman): Copyright, Contracts,
Defamation, Right of Privacy
B. R. Masters, Responsible Conduct of
Research
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BOOKS
• Andrews, LB, Mehlman, MJ, Rothstein, MA
Genetics: Ethics, Law and Policy, second
edition, St. Paul, Thompson/West (2006)
This book discusses genetics research, biobanks, research on
human embryos, commercialization of genetic research, and
medical applications of genetics, genetic testing, screening,
counseling, gene therapy, pharmacogenetics, and
enhancement; forensics, privacy and confidentiality
B. R. Masters, Responsible Conduct of
Research
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Colloquium on Advances in Linear and
Nonlinear Optical Microscopy
Confocal Microscopy to Nonlinear Optical
Microscopy: Principles, Instruments,
Applications and Limitations
Professor Barry R. Masters
Visiting Scientist
Department of Biological Engineering
Massachusetts Institute of Technology
Cambridge, Massachusetts
Barry R. Masters Confocal and Multiphoton
Microscopy
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References
• Noninvasive Diagnostic Techniques in
Ophthalmology, (Editor, Barry R. Masters),
Springer Verlag, New York, 1990
• Medical Optical Tomography: Functional
Imaging and Monitoring, Section Editor: B.R.
Masters, SPIE Optical Engineering Press, Section
V. Functional Imaging and Monitoring (Section
Editor: B.R. Masters), 1993
Barry R. Masters Confocal and Multiphoton
Microscopy
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References
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Selected Papers on Confocal Microscopy, (Editor, Barry R. Masters),
Milestone Series MS 131, SPIE Optical Engineering Press, Bellingham, WA,
1996
• Selected Papers on Optical Low-Coherence Reflectometry and
Tomography, (Editor, Barry R. Masters), Milestone Series MS 165, SPIE
Optical Engineering Press, Bellingham, WA, 2000
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Selected Papers on Multiphoton Excitation Microscopy,
(Editor, Barry R. Masters), Milestone Series, MS175, SPIE Optical
Engineering Press, Bellingham, WA, 2003
Barry R. Masters Confocal and Multiphoton
Microscopy
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References
•
"Biomedical Optical Biopsy" Vol. 2. Classic Articles in Optics and
Photonics on CD-ROM Series, OSA, Editors, R. R. Alfano and B. R.
Masters, Optical Society of America, Washington, DC, 2004
• Confocal Microscopy and Multiphoton Excitation Microscopy: The
Genesis of Live Cell Imaging. B.R. Masters, SPIE, Optical
Engineering Press, Bellingham, WA, 2006.
• Handbook of Biomedical Nonlinear Optical Microscopy, (Barry R.
Masters, Peter T. C. So, Eds.), Oxford University Press, 2008
• Super-Resolution Optical Microscopy, Barry R. Masters, Cambridge
University Press, NY (in preparation).
Barry R. Masters Confocal and Multiphoton
Microscopy
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Barry R. Masters Confocal and Multiphoton
Microscopy
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Barry R. Masters Confocal and Multiphoton
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Barry R. Masters Confocal and
Multiphoton Microscopy
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Reproduced with permission from: C.V. Raman, A Pictorial Biography,
S. Ramaseshan and C. Ramachandra Rao, Indian Academy of Sciences,
Bangalore, India, 1988
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Barry R. Masters
C.V. Raman: Discovery of
the Effect and Attribution of
Credit
Barry R. Masters,
Department of Biological Engineering,
Massachusetts Institute of Technology
Cambridge, Massachusetts
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Background, Education, and Professional Life
How did Raman discover the Raman Effect?
Raman’s equipment and experimental setup
Raman’s interests, research methodology, and his
scientific style
• Attribution of credit
• Research on Light Scattering in the 1920’s
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References and Resources
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C.V. Raman, The Molecular Scattering of Light, Nobel Lecture in
Physics, Dec. 11, 1930
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Raman Research Institute, Bangalore, India, www.rrr.res.in
Indian Academy of Sciences, Bangalore, India
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S. Ramaseshan and C. R Rao, C. V Raman, A Pictorial Biography,
Bangalore, India, Indian Academy of Sciences, (1988)
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The Collected Papers of C. V. Raman, six volumes, Bangalore, India,
Indian Academy of Sciences, (1988)
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A. Smekal, On the quantum theory of dispersion, Die
Naturwissenschaften, 11, 873-875, (1923).
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H. A. Kramers and W. Heisenberg, On the dispersion of radiation by
atoms. Zeitschrift für Physik, 31, 681-708, (1925).
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R. H. Stuewer,
The Compton effect: turning point in physics
Science History Publications, (1975)
D.L. Rousseau, P.F. Williams,
Resonance Raman scattering of light from a diatomic molecule
The Journal of chemical Physics, Vol. 64, No. 9, 3519-3537, (1976)
B. R. Masters,
C. V. Raman and the Raman Effect
Optics & Photonics News, March 2009, Vol. 20, No. 3, 40-45.
G. Venkataraman,
Journey Into Light, Life and Science of C. V. Raman
Indian Academy of Sciences, Indian National Science Academy,
Bangalore, 1988
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R. Singh, F. Riess,
The 1930 Nobel Prize for Physics: A close decision?
Notes & Records of the Royal Society, London, 55, 267-283 (2001)
Abha Sur,
Aesthetics, Authority, and Control in an Indian Laboratory,
The Raman-Born Controversy on Lattice Dynamics
Isis, 90: 25-40 (1999).
C. L. Braun, S. N. Smirnov
Why is Water Blue?
Journal of Chemical Education, 70(8), 612-614, (1993)
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• Why is Water Blue?
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Braun and Smirnov (1993 ref.)
Blue color of water is due to selective absorption of red part of visible spectrum.
Absorbed photons promote transitions to high overtone and combination states of
nuclear vibrations in water molecule-highly excited vibrations.
Only example in nature of color of substance due to vibrational transitions, usually
due to electronic transitions.
Question: why is a body of water, viewed in reflection blue?
Blue color is due to both reflected sky light and the absorption of red light due to
vibrational transitions in water molecules. The relative contribution of each to the
blue color is highly dependent on the observation angle.
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