Transcript Slide 1

UNITAID sets up programs for HIV / AIDS
malaria
1.900 new children affected
tuberculosis
each day by AIDS,
that is 1 child every 20 seconds
20% deaths among children
in Africa due to malaria,
a disease which can be cured…
Near 2 billion people
affected by tuberculosis,
that is one third of the world population
dedicated to Global solidarity
A Global State of Emergency…
Medicines are in the North, patients in the South
The less developed countries represent:
 84% of the world population

less than11% of the global health expenditure

more than 93% of the global disease burden
 2.1 million HIV positive children in
the world
 660,000 children need ARV
Only 40,000 benefit from it
 Drug resistance is increasing
 Only 8% of pregnant women get
ARV to prevent transmission of
the disease to their baby
 1st cause of child mortality for a disease
that can be cured
 The disease burden is growing
 ACTs are the most efficient treatment
against growing drug resistances
(efficient for 95% cases)
 2 million people die from tuberculosis
each year
 1st cause of mortality for people with Aids
 Drug resistance is growing
 Multi drug resistant treatments are
extremely expensive (4.000 $/year)
Official signature of the five founder countries when UNITAID was launched,
on 19 September 2006, United Nations, New York
27 donor countries already joined UNITAID
Guinea has just joined on 30th August 2007
Countries that implemented the air tickets levy
Tax already in place or now been implemented:
- France
- Chile
- Norway (tax on CO2 from airplanes)
- Côte d’Ivoire
- Congo
- Guinea Conakry
- South Korea
- Madagascar
- Mauritius
- Namibia
- Niger
Countries which have committed to implement the tax: Benin, Burkina Faso,
Cameroon, Gabon, Liberia, Mali, Morocco, Central African Republic, Senegal,
Sao Tome & Principe, Togo
More than 80% of UNITAID revenue
is based on the air ticket levy
UNITAID EXPECTED REVENUES 2006-2009
Brazil
Chile (1)
France (1)
Norway (1)
UK
Spain
New donors* (1)
% of airtickets levy or alike
( '000 $ US)
2007
2008
2009
10,000
6,049
212,598
21,625
26,490
10,000
3,500
215,054
22,000
40,323
10,000
3,500
215,054
22,000
69,893
20,161
10,000
------------318,023
20,000
80,000
------------390,876
20,000
150,000
------------490,446
84%
90%
90%
(1) airtickets levy or alike (CO2)
* includes Korea (15 M$) Cote d’Ivoire, Congo, Madagascar, Mauritius, Guinea Conakry and Niger (tax
already adopted) and 17 other countries where the tax is being implemented
The Gates foundation will also bring 10 M$ per year
Impact of the air tickets levy: an example
Tax received on
each ticket by
UNITAID (in France)
Flight in
France or in
Europe
International
flight
Economy class
First class or
business
1€
10 €
Antimalarial treatment
for 2 children
ex: flight Paris - Berlin
4€
40 €
1 HIV-positive child
under treatment
for 1 year
ex: flight Paris - Dakar
An aircraft with 300 passengers on board leaving from Paris will
cover the treatment for 1 person with multi drug resistant
tuberculosis, which is very expensive (approx. 4.000 $)
Furthermore… no economic impact on air traffic
UNITAID objectives
1/ Improve access to treatment for HIV/AIDS, TB, malaria in developing
countries
2/ Get lower prices for quality drugs and diagnostics
3/ Speed up products availability
 Predictable long-term funding
 A budget over $ 300 million in 2007, 90% being already committed
 Price reductions as a result of larger volumes (pool procurement)
 85% of funds for the poorest countries
 A small secretariat hosted by WHO: no bureaucracy
UNITAID added value
UNITAID use of funds allows to:
1/ have manufactured drugs better adapted to patient needs
(fix dose combinations)
2/ reduce prices: more drugs available for the same budget
3/ contribute to a better quality (pre qualification
of drugs, incentive for manufacturers to invest)
4/ rapidly deliver drugs in the countries in need
UNITAID uses a wide range of tools
to help reduce prices and accelerate
availability of drugs
Predictable funding
COST plus
pricing
Volume price negotiation
Encouraging/attracting
new manufacturers
Prequalification
Pool procurement
Market dynamics forecast
Information sharing
Encouraging
market competition
Encouraging
technology sharing
Supporting local registration
Lowering barriers
to entry on market
Partnership pricing
Reference price / price ceiling
A unique partnership model
UNITAID works together with well-recognized partners :
In the last months, UNITAID
has committed to funding projects
against the three diseases…
Ongoing UNITAID programs
HIV / AIDS
I/ Pediatric ARV: Have 100,000 new HIV-positive children under
adapted ARV treatments in 2007 (today only 40,000 are covered
when 660,000 need it) in 40 countries.
II/ 2nd line ARV: reduce prices for 7 products and provide treatments
for 60,000 new patients in 27 countries in 2007.
Partner: the Clinton Foundation
III/ Prevention of mother to child transmission: improve the care,
reduce diagnostic prices, have 1.2 million pregnant women tested
and 340,000 under ARV treatment in 8 countries in 2007-2008.
Partners: WHO and UNICEF
53 recipient countries from UNITAID funds
against HIV / AIDS
SEARO
AFRO
India
Angola
Thailand
Benin
Botswana
WPRO
Burkina Faso
Cambodia
Burundi
China
Cameroon
Lao
Chad
Papua New Guinea
DRC
Vietnam
Cote d'Ivoire
Ethiopia
AMRO
Ghana
Dominican Rep.
Guinea
Guyana
Kenya
Haiti
Lesotho
Jamaica
Liberia
OECS
(Anguilla,
Malawi
Dominica,
Mali
St Lucia,
Mozambique Antigua & Barbuda,
Namibia
Grenada,
St Christopher & Nevis,
Nigeria
British Virgin Islands,
Rwanda
Montserrat,
Senegal St Vincent & Grenadines)
South Africa
Swaziland
EURO
Tanzania
Moldova
Togo
Serbia
Uganda
Zambia
EMRO
Zimbabwe
Djibouti
Morocco
Tunisia
Ongoing UNITAID programs
Malaria
I/ ACT scale up: Scale up ACT treatments in eleven countries, until
2010, for 55 million treatments, in order to have an impact on prices,
give an incentive to manufacturers, avoid stock out in countries.
Partners: The Global Fund and UNICEF
II/ ACT program in Liberia and Burundi : Provide nearly 1.3 million
treatments in these two countries that had no coverage for 2007,
before other donors stepped in.
Partners: WHO and UNICEF
22 recipient countries from UNITAID funds
against malaria
AFRO
Burundi
Cote d'Ivoire
Eritrea
Ethiopia
Gambia
Ghana
Guinea
Guinea Bissau
Liberia
Madagascar
Mali
Mauritania
Mozambique
Namibia
Somalia
Zambia
EMRO
Djibouti
Sudan
SEARO
Bangladesh
Indonesia
WPRO
Cambodia
China
Ongoing UNITAID programs
Tuberculosis
I/ 1st line TB : Support the transitional provision of 740,000 treatments
in 2007-2008 for 18 countries and establish a strategic rotating
stockpile.
Partner: The Global Drug Facility
II/ Pediatric TB: provide treatments adapted to children in order to treat
150,000 children by the end of 2007.
Partners: WHO and UNICEF
III/ Multi drug resistant TB : Support the purchase of 4,700 treatments
in 2007 for 17 low income and lower middle income countries, with a
view to decreasing prices.
Partners: The Global Drug Facility and the Global Fund
58 recipient countries from UNITAID funds
against tuberculosis
AFRO
Benin
EURO
Burkina Faso
Azerbaijan
Cape Verde
Cameroon Bosnia-Herzegovina
Belarus
Congo Brazzaville
Bulgaria
DRC
Georgia
Cote d'Ivoire
Kyrgyzstan
The Gambia
Kazakhstan
Guinea
Moldova
Kenya
Tajikistan
Lesotho
Uzbekistan
Madagascar
Malawi
EMRO
Mali
Afghanistan
Mauritania
Djibouti
Mozambique
Egypt
Niger
Iraq
Nigeria
Lebanon
Rwanda
Pakistan
Somalia
Syrian Arab Rep.
Tanzania
Yemen
Togo
Uganda
Zambia
SEARO
Bangladesh
Bhutan
India
Indonesia
Myanmar
Nepal
Sri Lanka
Timor-Leste
WPRO
Cambodia
Lao
Philippines
Vietnam
AMRO
Dominican Rep.
Guatemala
Haiti
Facing a global state of emergency,
UNITAID contributes to bring solutions
In less than a year, UNITAID has
already achieved major results…
1/ First significant price reductions
40
30
20
10
0
30 November 2006
on antiretroviral
for HIV positive children
(with the Clinton foundation)
-10
-20
-30
-29%
-33%
-29%
-26%
-40
-39%
-50
-57%
-60
TDF
TDF+3TC
TDF+FTC
ddl
30
20
10
8 May 2007
0
on second-line
antiretroviral
-10
-20
-30
-27%
-23%
(with the Clinton foundation)
-32%
-40
ABACAVIR 300mg
TENOFOVIR 300 mg
TENOFOVIR 300mg/ LAMIVUDINE
300mg
ABC
LPV/r
UNITAID first results
"My long experience in public policy taught
me that even those who don't like taxes are
not reluctant to pay a contribution for a good
cause.
Thanks to UNITAID, we succeeded to lower
the annual cost of a treatment for a child
with AIDS from 196 $ to 60 $. Each citizen
who gets into an plane and pays its
contribution should reflects on that : with the
same amount of money, we save three time
more children.."
President Bill Clinton
Le Monde – 25th July 2007
2/ More user-friendly drugs
With UNITAID funding, new treatments put on the market
against HIV/AIDS are more adapted :
- Doses well adapted to children corpulence
- Drugs to be taken in the form of tablets (fix dose combination) :
1 tablet replaces several doses daily
- Heat stable drugs : no refrigeration needed anymore
- No need to dilute them in water (problem of access to drinkable water
in some countries).
Daily treatment for a patient
Pediatric DFC make easier
HIV/AIDS treatment, for
patients but also for
healthcare professionals.
3/ The first drugs already in the field…
against HIV/AIDS
100
Number of children under treatment
(000’s)
(31st May 2007)
Pediatric ARV program with the Clinton foundation
90
80
70
60
28,229 new
children
50
40
30
40,758 children
already under
treatment
20
10
0
Nov '06
Dec '06
Source: Clinton foundation
Jan '07
Feb '07
Mar '07
Apr '07
May '07 TOTAL
TO DATE
Results obtained: Impact for a patient
Jennifer
On admission
Atter 3 months
After 5 months
Pediatric ARV program with the Clinton foundation
Source: Partners In Health / Clinton foundation
Against malaria
Arrival on 12th June 2007 of 670,000 ACT doses in Liberia
that will help to prevent the death of 6,800 children per year
(partners: UNICEF / WHO)