Transcript Mountain West Research Consortium Clinical Translational

Mountain West Research Consortium
Clinical Translational Research –
Infrastructure Network
The Mountain West CTR-IN
Robert D. Langer, MD, MPH
Principal Investigator
Research Professor of Allied Health Sciences, UNLV
Associate Dean for Clinical and Translational Research and Professor
of Family Medicine-Las Vegas, UNSOM
NIGMS Award: 1U54GM104944-01A1
What is it?
$20.3m 5 year NIH Grant Proposal
under the IDeA Program
Involving 13 universities across
the 7 IDeA states in the Mountain
West Research Consortium
Support:
to foster Clinical and Translational Research
(CTR) according to NIH Definitions
for Core Resources to facilitate the development
of researchers moving into CTR
BOOTSTRAP CTR ACROSS THE
MOUNTAIN WEST
We will sink or swim based on the
increase in “R-level” translational
and clinical research that we
achieve across the region over
the next 4 years
“a rising tide that …
… lifts all ships.”
Who is in it?
 UNLV [host]
 UNR/UNSOM
 U. Alaska – Anchorage
 U. Alaska – Fairbanks
 U. Hawaii – Manoa
 Boise State U.
 Idaho State U.
 U. Idaho
 Montana State U.
 U. Montana
 New Mexico State U.
 U. New Mexico
 U. Wyoming
What will it do?
Provide pilot grant support of $50,000 $75,000/year
Support Mini-Sabbatical and Visiting
Scholar awards to build collaborations
Provide infrastructure and services
through Key Component Activities
Funding preference
Promising Early Career or New
Investigators developing clinical or
translational research programs
Established Investigators moving from
bench to translational or clinical
Projects focused on health issues
relevant to the region, including those in
rural and vulnerable populations
What will it do?
Use an NIH-style approach to
applications and funding
Model the processes that clinical and
translational investigators need to
master to compete successfully for
NIH support
Key Component Activities (KCAs)

Education, Mentoring & Career
Development KCA

Study Design & Biostatistics KCA

Pilot Grant KCA

Administrative KCA, including editorial
support, award management, Annual
Meeting
Education
Mentoring
Study Design
Biostat
Annual Meeting
ALL AVAILABLE regardless of
whether you’ve received a
competitive award from the CTR-IN
What will it do?
Hold an Annual Meeting to share science,
motivate, build collaborations, & conduct
study business that will:
 rotate across the 13 partner institutions
 feature an annual research theme relevant to
health in the region
 bring together supported investigators, interested
researchers from the region, key administrators
from partners, external scientists, the regional
biostat team, and senior project staff
First Annual Meeting at UNLV June 23 – 25, 2014
free registration, hotel rate ~ $100/night
What’s the current status?
Round 1 Pilot Grants:
24 applications, 6 awarded
Round 1A Pilot Grants:
63 applications, 14 awarded
Year 1 Pilot Grants
Round 1
Round 1A
Total
Boise State
0
3
3
Idaho State
0
1
1
Montana State
2
1
3
New Mexico State
0
1
1
U Alaska - Anchorage
0
1
1
U Alaska - Fairbanks
0
1
1
U Idaho
0
1
1
U Montana
2
0
2
U Nevada Las Vegas
1
3
4
U Nevada Reno
1
1
2
U Wyoming
0
1
1
6
14
20
What’s the current status?
 Round 2 Pilot Grant RFA for 7/1/14 – 6/30/15:
 Letters of Intent with Abstacts were due 3/7/14
 122 LOIs with Abstracts received
 Invitations to submit 3/14/14
 Applications due 4/25/14
 Awards announced at Annual Meeting 6/25/14
 Earliest start date 7/1/14
 All information at: ctrin.unlv.edu
Letters of Intent for Year 2 Pilot Grants
U. Alaska Anchorage
U. Alaska Fairbanks
8
5
Boise State U.
Idaho State U.
U. Idaho
3
14
8
Montana State U.
U. Montana
New Mexico State U.
UNR
7
5
9
23
UNLV
U. Wyoming
30
10
Total 122
Visiting Scholars
 Call still open
 Funds must be expended by 06/30/14
 4 applications to-date, all awarded
 U Montana – to PG Awardee
 UNLV – to PG Awardee
 U Hawaii
 UNLV
PEOPLE!
Your First Call …
the ISU Concierge
Dr. Rex Force
Senior Leadership
Administrative Core
Education & Mentoring
Bob Langer, UNLV, PI
Jillian Inouye, UNLV, Directorer
Jim Kenyon, UNR, Proj Coord.
Bruce Shiramizu, UH, Mentoring
Carl Reiber, UNLV, Assoc. Dir.
Pope Moseley, UNM, Mentoring
John Foreyt, UNSOM, Eval. Dir.
Merle Kataoki-Yahiro, UH, Educ
Craig Molgaard, UMT, Educ
Pilot Grants
Curtis Noonan, UMT, Director
Design, Epidemiology, Biostat
Bill Shuttleworth, UNM, Assoc. Dir.
Pope Moseley, Director
UNM CTSA: Richard Larson
website
ctrin.unlv.edu
NIGMS Award: 1U54GM104944-01A1
What are the 7 Mountain West states?
Alaska
Hawaii
Idaho
Montana
Nevada
New Mexico
Wyoming
What will it do?
 Identify, support, and facilitate promising researchers to
achieve independent success as with R-level funding
from the NIH
 Foster collaborations to leverage regional expertise to
develop robust clinical and translational programs
 Engage the consortium of regional biostatisticians to
develop innovative methodology and novel applications
of existing tools
 Engage successful researchers from outside the region
as an External Advisory Committee providing experience
and expanded reach
Mountain West CTR-IN Organizational Structure
Governance and Membership
Steering Committee
Robert Langer, MD, MPH, Principal Investigator
Jim Kenyon, PhD, Project Coordinator, Partners
John Foreyt, PhD, Project Coordinator, T&E
Rafael Gorospe, MD, PhD, Project Officer
Maria Canto, DDS, MS, MPH, Project Scientist
AFFILIATION COLOR
CODE
UNLV
UNSOM
U. New Mexico
U. Montana
NIH
Other Institutions
Internal Advisory Committee
Carolyn Yucha, PhD, Co-Chair
Thomas Schwenk, MD, Co-Chair
VPRs of all 13 Partner Universities
Robert Langer, MD, MPH, PI, ex oficio
Jim Kenyon, PhD, Project Coordinator, ex oficio
Principal Investigator
Admin KCA
Executive Committee
Robert Langer, MD, MPH
Robert Langer, MD, MPH, KCA Director
Carl Reiber, PhD, Assoc. Director
Jim Kenyon, PhD, Project Coordinator
Track & Eval Unit
Concierges
John Foreyt, PhD,
Project Coordinator
Jill Zimbelman,
Lead Concierge
Regional Network
PI
2 Project Coordinators
3 [4 with PI] KCA Directors
Assoc. Director, Admin KCA
Lead Liaison
CTSC Coordinator
External Advisory Committee
6 to 10 External Scientists
from outside the 7 state region
Educ & Mentoring KCA
Jillian Inouye, PhD, KCA Director
Mentoring Unit
Education Unit
UNM CTSC
Richard Larson, MD, Coord.
Pilot Grant KCA
CRDEB KCA
Curtis Noonan, PhD, KCA Director
Pope Moseley, MD, KCA Director
Regional Biostatistician Network