Transcript Preparedness, Prevention and Contingency(PPC) Plan

How to write
STANDARD OPERATING PROCEDURES (SOP’s)
STANDARD OPERATING PROCEDURES
• Definition: A standard operating procedures (SOP) is set of
written procedures explaining how to safely work with
hazardous chemicals.
• Why SOP's Are Required: In order to ensure the safety of all
members of the lab and to make the Laboratory and
Research Safety Plan a legal document, principal
investigators must add laboratory specific procedures to
the plan.
• When SOP's Are Required: SOP's are required additions to the
Laboratory and Research Safety Plan in any laboratory
engaging in activities not otherwise covered by the Plan.
GUIDELINES FOR PREPARING SOP's
Three methods that can be used to
write SOP's:
• By Process: (distillation, synthesis, chromatography, etc.)
• By Individual Hazardous Chemical: (arsenic, benzene,
hydrochloric acid, etc.)
• By Hazardous Chemical Class: (flammable, corrosive,
oxidizer, etc.)
Section 1: Determine the appropriate
method:
• Process (i.e. distillation, synthesis,
chromatography, etc.)
• Hazardous Chemical (i.e. arsenic, benzene,
hydrochloric acid, etc.)
• Hazard Class (i.e. flammable, corrosive,
oxidizer, etc.)
Section 2: Describe Process,
Hazardous Chemical, or Hazard Class
Process ‐ Describe the process which involves hazardous chemicals. List all
chemicals used in the process.
Hazardous Chemical ‐ Name the hazardous chemical for which the SOP is
being developed. Include IUPAC (International Union of Pure and
Applied Chemistry), common name, and any abbreviation(s) used
for the chemical.
Hazard Class ‐ Describe the hazard associated with a particular group of
similar chemicals and list the chemicals used in the laboratory.
Section 3: Potential Hazards
Describe the potential hazards for each process,
hazardous chemical, or hazard class. Include
physical and health hazards. Such as fire,
explosion, burns to the skin, toxic fume
generation, absorption through the skin, or
cancer suspect.
Section 4: Personal Protective
Equipment (PPE)
• Identify the required level of personal protective equipment
and hygiene practices needed for each process, hazardous
chemical, or hazard class.
• Eye protection must be made available to all employees and
visitors to the lab. Skin and body protection involves the
use of PPE to protect against chemical exposure.
• Personal protective equipment includes (but is not limited to):
gloves, aprons, lab coats, safety glasses, chemical splash
goggles and face‐shields.
Section 5: Engineering Controls
Describe engineering controls that will be used to
prevent or reduce employee exposure to hazardous
chemicals for the process, hazardous chemical, or
hazard class. This includes ventilation devices such as
fume hoods, glove boxes, etc.
Section 6: Special Handling & Storage
Requirements
List storage requirements for the hazardous chemicals
involved in the SOP, including specific storage areas,
storage according to compatibility and policies
regarding access to chemicals. Special procedures such
as dating peroxide forming chemicals upon receipt,
and opening and testing for peroxide formation
after the appropriate date (i.e. diethyl ether).
Section 7: Spill and Accident
Procedures
Indicate how spills or accidental releases will be handled and by
whom. List the location of appropriate emergency equipment
(spill kits, showers, eye washes, and fire equipment).
Any special requirements for personnel exposure should also be
identified in this section. Identify the location of emergency
response phone numbers.
Section 8: Decontamination Procedures
If items such as glove boxes, hoods, lab benches and
controlled areas have been contaminated by hazardous
chemicals, remove chemical contaminants with
appropriate solvents or cleaning solutions.
Section 9: Waste Disposal Procedures
Indicate which materials or substances will
require disposal as hazardous waste. Each
container of hazardous waste must be labeled
with a completed red waste tag attached. Red
Tags are available through EHS.
Section 10: Material Safety Data
Sheet Location
MSDS's are available from the EHS website,
www.ehs.psu.edu, by googling the chemical
name online, or by contacting EHS.
Also, indicate the location of other pertinent
safety information, i.e. equipment manuals,
chemical references, etc.
Section 11: Protocol(s)
Insert a copy of your specific laboratory
procedures for working with this particular
process, hazardous chemical or hazard class.
HYDOFLUORIC ACID
Hydrofluoric Acid
SOP
Section 1: HAZARD CLASS
Hydrofluoric acid (HF) 70% and diluted
solutions. DANGER, strong corrosive, highly
toxic, acutely toxic.
Section 2: DESCRIBE PROCESS, HAZARDOUS CHEMICAL
OR HAZARD CLASS
Mineral digestion, surface cleaning,
etching and biological staining.
Section 3: POTENTIAL HAZARDS
Extremely corrosive and destructive to tissue. specialized
medical treatment is required for all exposures. May be
fatal if inhaled, absorbed through skin, or swallowed. May
cause depletion of calcium in the body which may be
fatal. Skin contact results in painful deep‐seated burns
that are slow to heal. Far more care is needed with HF
than other acids.
Section 4: PERSONAL PROTECTIVE
EQUIPMENT
Chemical splash goggles, thick neoprene
chemical resistant gloves and lab coat. Thick
neoprene gloves, lab coat, neoprene apron,
chemical splash goggles and a face shield
should be used for handling quantities over 1
pint.
Section 5: ENGINEERING or VENTILATION
CONTROLS
Handle HF solutions in a fume hood or use other
suitable local exhaust.
Section 6: SPECIAL HANDLING PROCEDURES
& STORAGE REQUIREMENTS
• Extreme care must be taken to prevent conditions that would lead to spills
or splashes of hydrofluoric acid. Make everyone who handles or uses HF aware
of its properties and dangers. Train everyone who uses HF in proper handling
and safety precautions. Utilize all appropriate engineering controls, and making
sure that the controls are maintained and functioning properly. Require
everyone who handles HF to have the proper safety
and personal protective equipment. Arrange ahead of time to
provide first aid or medical treatment measures if necessary.
• Store hydrofluoric acid in a secondary polyethylene container.
Hydrofluoric acid can be stored with other mineral acids. Glass and
silicate‐containing materials are attacked by hydrofluoric acid.
Hydrofluoric acid reacts with metal to produce flammable hydrogen gas.
Section 7: SPILL AND ACCIDENT
PROCEDURES
Plan first aid action before beginning work
with this product. Always have on hand a first
aid kit containing 2.5 % calcium gluconate gel.
For any splash to skin, eyes or inhalation, call
911 immediately.
Section 7: SPILL AND ACCIDENT
PROCEDURES
Skin Contact
Limit washing to 5 minutes if treatment specific for HF
exposure is available. Remove all contaminated clothing
while washing continuously. After thorough washing for
at least 5 minutes, 2.5% calcium gluconate gel may be
continuously massaged into the burn area until the pain
is relieved. Get medical attention immediately by
calling 911.
Section 7: SPILL AND ACCIDENT
PROCEDURES
Eye Contact
Irrigate eyes for at least 15 minutes with copious
quantities of water, keeping eyelids apart and away
from eyeballs during irrigation. Get medical
attention immediately by calling 911.
Section 7: SPILL AND ACCIDENT
PROCEDURES
Inhalation
Remove to fresh air. Keep patient warm and at
rest. Get medical attention immediately by calling
911. If breathing has stopped, start artificial
respiration at once.
Section 8: DECONTAMINATION
PROCEDURES
Neutralize any contaminated surfaces or equipment
with sodium bicarbonate solution.
Section 9: WASTE DISPOSAL
PROCEDURES
Collect waste in original plastic shipping
container or in suitable plastic (polyethylene)
waste container. Do not use glass or metal
containers. If possible, do not mix with other
waste materials.
Section 10: MSDS LOCATION
http://www51.honeywell.com/sm/hfacid/common/
documents/MSDS_HF_70_V1_technical_doc.pdf
Laboratory Chemical Safety Summary: Hydrogen Fluoride and
Hydrofluoric Acid
http://books.nap.edu/openbook.php?record_id=4911&page=338
Recommended Medical Treatment for Hydrofluoric Acid Exposure
http://www.colorado.edu/ehs/pdf/HWMedHFExpo.pdf