Il progetto INFN-MED

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Transcript Il progetto INFN-MED

Highlights from INFN-MED

the INFN strategic project for Medicine

Areas of interest:

Imaging

Treatment Planning and Software projects

Accelerator devices for Hadron Therapy

BNCT

Devices for Medical Diagnostics

Imaging: MAGIC-5 Project

Fall out from the experience in the analysis of particle phyiscs experiments

A highly competitive lung CAD (Computer Assisted Detection) has been developed, capable of speeding up diagnosis response in case of large screenings.

Based on the development of different and complementary pattern recognition algorithms

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Several recognitions at international level.

Looking for an industrial partner to turn the prototype into a market product

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Neuroimaging

For the understanding and early diagnosis of pathophysiological mechanisms of neurodegenerative diseases (for instance Alzheimer Disease) Promising results work with the European Alzheimer’s Disease Consortium (EADC) Plans:

Full MRI/PET combined analysis

Development of more efficient computational tools

WWW access to the clinical world Furthermore, side product from Magic-5: development of an innovative web service to manage Clinical Trials ( diXit ). Particularly useful for the experimentation in pharmacology

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Treatment Planning System for therapy with C ions

Fall out from the experience in software management, simulation tools, radiobiology and nuclear phsycs

Collaboration Agreement with IBA . Development of .innovative system to be embedded in the “Oncology Information System” (OIS) in a configuration known under the name of MOSAIQ-RTP (Commercialized by Eleckta-CMS, controlled by IBA) 4

Status of development

To Be Released October 2010 Plan To Be Released April 2010 Released April 2010 Released August 2010 To Be Released January 2011

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Complete the design of a new Accelerator Source: MISHA

Multicharged Ion Source for HAdrontherapy

At CNAO center for hadrontherapy two ECR sources of the SUPERNANOGAN type (built by the Pantechnik company according to specifications set by INFN) are in operation.

A further increase of to provide more than 600 accelerator reliability involves the improvement of the beam brightness, which can be achieved with the design and construction of a new ECR ion source, able eµA of C 4+ with an emittance figure of 0.75

π mm. mrad.

The MISHA source will be a multipurpose device, providing enough versatility for future needs of the hadron therapy. The MISHA source has been designed on the basis of the expertise existing in INFN Labs (LNS and LNL, G. Ciavola et al.)

Of interest for all accelerators for hadrontherapy

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Maximum radial field Maximum axial field Frequency Maximum RF power Maximum extraction field Chamber diameter LHe 1.3 T 2.5 T / 1.5 T 18 GHz + 17.8 GHz 500 W + 500 W 50 kV Ø 92 mm free

External Funding is being searched for (~1.5 M € needed)

General layout of the MISHA source and of its Low Energy Beam Transfer line

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MID (under completion)

Fall out from the experience in the development of high precision magnetic apparata in particle physics.

First device capable of measuring the amount of Fe in human organs in a non invasive way (i.e. avoiding biopsy).

From the experience of INFN Genova, co-financed and in under operation in Galliera Hospital (Genova).

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ECORAD

Fall out from the experience in the development of new particle detectors

Now exploring Patent/Technology Transfer possibilities Resp.: R.Pani, INFN and Roma 1 Univ.

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New possibilities

Design study for a facility to produce Radionuclides for Medicine using the new cyclotron at LNL

LARAMED A first presentation of the project will take place in LNL/Padova at the end of November:

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Relationships with CNAO and Healt Ministry

 Monitoring cooperation with CNAO foundation for hadron therapy in view of:  MC Simulation  Pre-clinic activity  Treatment Plannig evolution  Definition of collaboration agreement with Health Ministry for scientific exchange, relationship with industry in medical sector, cofinancing of activities of common interest 12