HST.921 HST.922 HST.923 HST.924 Spring 2014

Enabling Technology Innovation in Healthcare and the Life Sciences

Steven Locke, MD

Course Co-Director

Bryan Bergeron, MD

Assistant Directors

Mirena Bagur

Course Co-Director

Chandrika Samarth, MBA

Course Fellow

Agenda

• Course Mission Statement • Course Overview – Faculty, Students, and Sponsors – Lectures – Tutorials – Practicum – Projects and Final presentations • FAQs – Registration & Credit • Q&A • Contact

HST.921: Enabling Technology Innovation in Healthcare and the Life Sciences http://hst921.org

Lectures: Tuesdays, 4:00-5:30pm Tutorials/Lab: Tuesdays, 5:45-7:00pm Place: MIT E51-151 Classes start Tuesday, Feb 4th

Mission Statement To empower students to: critically analyze a current - problem in health care and the life sciences, and or future - working in teams, develop a novel solution using information technologies.

Course Faculty

Steven Locke, MD

Research Psychiatrist, Division of Clinical Informatics Beth Israel Deaconess Medical Center Associate Clinical Professor of Psychiatry, Harvard Medical School Affiliate Faculty, Division of Health Sciences and Technology, MIT

Bryan Bergeron, MD

President, Archetype Technologies Assistant Professor of Health Sciences and Technology, MIT

Mirena Bagur

CONTeXO Group The Capital Network MIT Enterprise Forum MTLC Affiliate Faculty, Division of Health Sciences and Technology, MIT

Chandrika Samarth, MBA

Course Fellow Director of research at a grant funded start up

Industry Mentors

• Winfried A. Burke – CEO, iGetBetter; serial entrepreneur/software • Francis X. Campion, MD – Vice President of Clinical Affairs, Alere Analytics – Diplomate, Clinical Informatics, American Board of Preventive Medicine • Renu Chipalkatti – Executive Director, Healthcare and Incubation @ Verizon Enterprise Solutions • Greg Erman – CEO, lecturer, serial entrepreneur, med devices • Mark Hauser, MD – OnSite Psychiatric Services

Expert Panelists

• Daniel Sands, MD • Lynne Dunbrack • David Judge, MD • Craig Schneider, Ph.D

• Al Lewis, JD • Christian Cortis • Anita Goel, MD, Ph.D

• Deb Theobald • Richard Anders • Peter Lomedico • Josh Feast • Stan Nowak • Michael Lemnitzer Change Agent in Doctor Patient Comm Analyst, IDC – Health Industry Insights CIMIT Mass Health Data Consortium Founding President, DMAA Partner, ATVentures CEO, Nanobiosym CEO, VECNA Investor, Mass Medical Angels Juvenile Diabetes Foundation CEO, Cogito Health CEO, SilverLink Philips Telehealth

Student Comments

"HST921 was an incredible experience for me. It was an excellent opportunity to meet face-to-face with recognized leaders in the field who are working on really difficult problems and willing to mentor students who are interested in getting involved. HST921 is both an industry overview and an entrepreneurship class in one - which was exactly what I was looking for.” -- Krishna Yeshwant, Harvard MD/MBA 2009 2008 MIT $100K Competition winner and 2008 Harvard Biz School Competition winner

Students

Harvard • HMS • HSPH • HBS • KSG • HGSE • FAS • HLS • Affiliated hospitals MIT • HST • Computer Science • Electrical Engineering • Biomedical Engineering • Media Lab • Sloan School

Sample lectures & tutorials

Title Welcome & Course Introduction Lecture: A Perspective on HIT and Innovation Industry Overview: The Future of Healthcare Federal Policy as a Driver for HIT Innovation Medical Network Innovation in an Enterprise/Intrapreneurship Faculty Course Faculty Steven Locke, MD + expert panel Karen Bell, MD, MPH Daniel Sands, MD, MPH John Glaser, PhD Classroom simulation: product design process Bryan Bergeron, MD Population Management and Patient Engagement in Self-Care Investors’ View of Startups Consumers in Healthcare: Patient Power, Medical Home, Patient-Centric Care Starting Up: Funding Sources for For-profit and Social Entrepreneurship Innovation Examples in Various Companies Entrepreneurs Panel Steven Locke, MD + expert panel Eugene Hill, MBA Bryan Bergeron, MD + expert panel expert panel Expert panel Steven Locke, MD + entrepreneurs Project Presentations I Project Presentations II Student teams Student teams Tutorial/Practicum Projects’ descriptions and overview Project presentations Project Assignments Tutorial: Makings of a team Definition of Elevator Pitch Key Elements of Business Plan Simulation debrief Practice elevator pitch Deliver “elevator pitch” Mentor/Team Session Mentor/Team Session Mentor/Team Session Final Team Q&A w/Mentors

Projects & Final Presentation

Group Design Projects

• Student driven • Corporate partner driven • Multidisciplinary teams • Tracks – Design, Business, Marketing, Trials • Class exercises (design, elevator pitch) • Group final presentations and paper

Common Elements

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Objective of the group project Proposed product or service solution Industry summary Analysis o o o o o Problems with current solutions Competitive analysis Porter model Evaluation of macro-industry forces Micro-stakeholder analysis Interaction diagrams Reflection on cost, quality, and access

Project Track Selection

• Track 1: Marketing Analysis • Track 2: Business Plan • Track 3: Product Design Plan • Track 4: Clinical Trial/Product Evaluation Each team chooses two out of four

Market Analysis and Plan

1. Market Background 2. Future Directions of Market 3. Market Size/Forecast 4. Customers/Customer Segmentation 5. Target Market Segments 6. Product Description 7. Pricing 8. Promotion 9. Sales and Distribution Strategy

Business Plan

1. Partnering 2. Staffing Plans 3. Advisory Board 4. Risk Management ( analysis of specific risks and address various scenarios ) 5. Financial Projections and Resources Required 6. Near Term Milestones and Expenses 7. Long Term Projections

Product Design

The Product 1. Product Definition and Goals 2. Product Requirements/ Specifications 3. Expected Product Lifecycle 4. Product Add-ons, Third Party Tool Sets 5. Follow-on Products User Profile 1. Job Description 2. User Skills, Knowledge and Education 3. Work Style 4. Concerns 5. Wants 6. Requirements 7. Work Environment

Clinical Trial

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Rationale Objectives Study design and hypotheses Participants Intervention Primary and secondary endpoints Sample size (optional) 8.

9.

Anticipate time frame for study completion Data collection; sub-protocols, intervals, encounters, events 10. Analysis

Sample Student Projects

• Student provided project: MedGenuity - Engineering a Premium Platform for Providers • Dossia Consortium -Evaluating the Proposition for PHR: Strategic Analysis & Product Evaluation • Intel - Medication Adherence 2.0

• Insurance Company - Exploration of social networking technologies to engage health care consumers • Symantec - Utilizing the latest technology to easily and securely view & share diagnostic images and reports • J&J - Empowering Consumers and Physicians via Consumer-led Social Media Networks • Healthways - Improving Physician Engagement Through Technology • Careplace - Online Health Consumer Empowerment, Advocacy, and Support • Technology Opportunities in Healthcare for the Baby Boomer Generation • Computer-Assisted Disease Management to Improve Outcomes in Diabetic Patients

Sponsors:

Corporate Partners Other Participating Organizations • Archetype Technologies, Inc.

• The CONTeXO Group • iHope, LLC

Student Comments

“HST.921 unified business, science, and medicine with a set of uncommon learning objectives, focused on developing skills on how to pursue ideas and get things done in the real world. The curriculum was phenomenal. Best of all, I met some very talented classmates and teachers with whom I share ideas on a frequent basis. Two thumbs up!” Eugene Chan, MD Physician-Innovator-Entrepreneur Director/The DNA Medicine Institute

FAQ’s

• Project selection • Required readings • Required paper • School-specific credit • Work load • Attendance • Professional standards • Course auditing

Registration and Credits

MIT Students Go to WebSIS ( registration .

student.mit.edu

) and follow links to pre registration. Add HST.921 and HST.923 to your pre Harvard Students https://crossreg.harvard.edu/OASIS/CrossReg/ Cross-Registration Credit Calculator https://crossreg.harvard.edu/OASIS/CrossReg/credit.jsp

Registration Credits

Grade Lecture HST.921

HST.922

Tutorial HST.923

HST.924

P/F Ordinal P/F Ordinal Full Credit Half Credit HMS HSPH KSG HBS MIT 2 2 2 2 4 2 2.5

2.5

2.5

2.5

5 2.5

0.5

0.5

0.5

0.5

1 0.5

N/A* N/A* N/A* N/A* N/A* N/A* 9 9 3 3 12 9 *can arrange as independent study for credit

Questions and Discussion

Workshop

https://www.leapmotion.com/

Workshop = 45 minutes

• Two teams • Each define their idea of how LeapMotion can be used in healthcare or life sciences – 20 min brainstorm • Answer these questions: – What does the product do?

– How will you make money on the product? – How will you get the money to create a business that will develop the product?

• One member of the team presents the group’s answers in about 5 min • Follow-up conversation – 20 min

HST921: Contact Info

• Mirena Bagur – 617-835-5019 – [email protected]