Transcript Slide 1

The NIH Common Fund
James Anderson, M.D., Ph.D.
Director
Division of Program Coordination, Planning, and
Strategic Initiatives
October 27, 2011
Common Fund
Programs FY2011
HR-HR
Molecular Libraries
Interdisciplainary Research
CTSAs/Clinical Research
Training
HMP
Epigenomics
Nanomedicine
HRHR
NCBCs
Protein Capture
KOMP
Epigenomics
TCNPs
HMP
LINCS
CTSAs
Structural Biology
IR
Molecular
Libraries
Health Economics
Science of Behavior
Change
GuLF Study
NIH CRM
Global Health
Regulatory Science
GTEx
Common Fund programs catalyze research across a
broad spectrum of diseases/conditions
■ Enabling Infrastructure
Rapid Access to Intervention Development (RAID)
■ Molecular Libraries and Imaging
■
■ New Tools, Technologies, Data
■
■
Library of Integrated Networks of Cellular Signatures (LINCS)
Human Microbiome Project
LINCS is providing comprehensive data on the global
response of signaling networks to perturbagens.
Cell types
Data
generation,
analysis,
integration
Perturbagens
Functional
annotation
with existing
knowledge
Questions for LINCS to consider in planning for its
second phase:
1. Is the program truly transforming – could it dramatically affect how biomedical
research is conducted within a predictable timeframe?
2. Can the transformative outcome be accomplished or milestones reached within
the 5-10 yr period of funding from the Common Fund?
3. Will the outcomes synergistically promote and advance the individual missions
of NIH ICs to promote health? CF programs should enable, strengthen, and
promote IC-funded research.
4. Is the program sufficiently complex that it requires coordination of the efforts
of multiple ICs? Is the initiative not easily assignable to the mission of a single
IC?
5. Is the proposed initiative something that no other entity is likely or able to do?
If other entities are also engaged, what is the gap that the CF will fill? How will
related activities be coordinated?