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Weapons of Mass Destruction & Bioterrorism Ronald R. Blanck, D.O. LTG, USA (Retired) President University of North Texas Health Science Center WMD & BIOTERRORISM DUCT TAPE STOCKPILING ANTIBIOTICS GAS MASKS MAJOR BEHAVIOR CHANGE “…any explosive, incendiary, or poison gas, bomb, grenade, rocket having propellant charge more than four ounces, missile having an explosive charge of more than one quarter ounce, mine or device similar to the above…poison gas…disease organism…radiation.” “…any weapon or device that is intended, or has the capability, to cause death or serious bodily injury…through the release of…poisonous chemicals…disease…or radiation….” WMD : Significant casualties from terrorist use of: Nuclear Device Chemical Device ● Tabun (GA) ● Sarin (GB) ● Soman (GD) Biological Device ● ● ● ● Botulism Toxin Anthrax Plague Ricin Large Conventional Explosive Device Terrorism Is… “Warfare deliberately waged against civilians with the purpose of destroying their will to support either leaders or policies that the agents of such violence find objectionable.” Lessons of Terror - Caleb Cobb KILL ONE FRIGHTEN 10,000 -- Tom Clancy The Sum of All Fears Presidential Decision Directive 39 U.S. Policy on Counterterrorism June 21, 1995 PRESIDENT HOMELAND DEFENSE Governor Tom Ridge NATIONAL SECURITY COUNCIL Coordination of Federal Agencies FEMA FBI INCIDENT FEDERAL CONTINGENCY PLANS RESPONSE PLAN Crisis Management Consequence Management Definitions ● Crisis Management - Measures to anticipate, prevent, and/or resolve a terrorist threat or incident ● Primary Responsibility: Federal Government ● Lead Federal Agency: FBI ● Consequence Management - Measures to alleviate the damage, loss, hardship, or suffering caused by incident ● ● ● Primary Responsibility: State/Local Government Lead Federal Agency: FEMA, coordinating Federal Consequence Management support to the state Programs ● Domestic Preparedness - Interagency effort directed by Congress - AKA: Nunn-Lugar Domenici City Training ● Consequence Management Program - DoD efforts directed by SECDEF (DRID #25) - Improve DoD support for response to WMD attacks - Integrate National Guard and Reserve components Purpose of Nunn-LugarDomenici ● To enhance the capability of the Federal Government to prevent and respond to terrorist incidents involving weapons of mass destruction ● To provide enhanced support to improve the capabilities of state and local emergency response agencies to prevent and respond to such incidents at both the national and local levels Domestic Emergency Continuum Probability Most Likely Least Likely -- IND Greatest IBD -ICD -IED -- Impact Civil Disturbance -- HURRICANE WMD HAZMAT -Severe T-Storm -Civil Demo -- MAJOR FLOODING -- Aircraft Accident STATE & LOCAL FEDERAL Tiered Disaster/Emergency Response Federal Response State Response Local Response Incident Commander ● Full response requires local, state, and federal assets ● State response includes National Guard ● Military support requires Total Force involvement Overall Plans Logistics Information Equipment Comm. Command Scenario Capacity Federal WMD Response Assessment Radiological Threat (Plutonium) Summary: Terrorists place a radiation Dispersal Device which distributes plutonium over a populated area. Nuclear Explosion Threat (Uranium) Summary: An improvised nuclear device (1.5KT) is exploded at midday in the vicinity of a state capitol building. Biological Agent Threat (Anthrax) Summary: 100 grams of anthrax released into the air distribution system at a major airport. Chemical Nerve Agent Threat (GB) Summary: 10 Gallons of Sarin is released on a busy morning in trash canisters at 5 Subway stations in a major city. Chemical Nerve Agent Threat (VX) (Persistent) Summary: M23 Land mines (.8lb) placed in suitcases at major airport and exploded at midday It’s not IF, It’s WHEN and WHERE? * Bottom Line - we are not ready! Biological Warfare The intentional use of microorganisms or toxins derived from living organisms to produce death or disease in humans, animals, or plants Biological Warfare History ● 14th Century: plague at Kaffa ● 18th Century: smallpox blankets ● 1943: USA program established ● 1953: Defensive program established ● 1969: Offensive program disestablished ● 1979: Sverdlovsk Anthrax incident ● SE Asia: Yellow Rain ● London, Virginia: Ricin BW Agreements ● 1925 Geneva Protocol ● 1969 Nixon renounces BW ● 1972 Biological Weapons Convention ● 1975 Geneva Conventions Ratified Biological Weapons Policy ● No use under any circumstance ● Research limited to defensive measures ● We possess NO weaponized biologicals ● Previous weapons stocks destroyed ● Destruction supervised: - USDA - DNR of AR, CO, MD - Dept of HEW Destroyed U.S. Biological Warfare Agents ● Lethal - B. anthracis - Botulinum toxins - F. tularensis ● Anticrop - wheat stem rust - rye stem rust - rice blast ● Incapacitating - Brucella suis - Vee virus - SEB - Q fever agent The Sverdlovsk Incident ● April-May 1979 - 66 Anthrax fatalities ● 1988 - Soviets present data: ● 96 cases ● 79 gastrointestinal ● May 1992 - Yeltsin admits “military developments” Soviet BW Priorities “Agents Likely to be Used” ● ● ● ● ● ● ● ● ● ● Plaque Anthrax Botulism VEE Tularemia Q Fever Marburg Influenza Melioidosis Trphus “There were more INSTITUTES working on Plague in the USSR than PERSONNEL working on Plague in the USA” -- Dr Ken Alibek Advantages of BW: Are Biologicals the Ultimate Weapon? ● ● ● ● ● ● ● ● ● ● Agents easy to procure Inexpensive to produce Can disseminate at great distance Agent clouds invisible Detection quite difficult First sign is illness Overwhelms medical capabilities Simple threat creates panic Perpetrators escape before effects Ideal terrorist weapon Acquisition of Etiologic Agents ● Multiple Culture Collections ● Universities ● Commercial Supply Houses ● Foreign Laboratories ● Field Samples or Clinical Specimens Hazardous Biologic Material ● Letters ● Packages ● Cultures ● Person – to – Person ● Airborne Distribution Response ● Not Typical First Responders ● BIO First Responders - Health Providers - Public Health ● All Organizations Involved Issues ● Rapid Detection ● Public Health ● Hospital Capacity ● Stockpiling ● Vaccine Production Health Providers’ Responsibilities ● ● ● ● ● Awareness Presumptive Diagnosis Reporting Epidemiology Response -Triage -Prophylaxis -Immunizations -Treatment ● Risk Communications RECOMMENDATIONS 1. Be aware 2. Do not over – react 3. Listen to authorities 4. Take common sense precautions - radio and batteries - 3 - 5 day supply of food and water - full tank of gas - location of shelters 5. Participate in planning 6. Continue usual behavior It’s not a question of if... 26 February 1993, New York 20 March 1995, Tokyo It’s not even a question of when… a question of when 19It’s April 1995, Oklahoma City next… 11 September 2001, New York