Transcript Slide 1
School of Dentistry and the Oral Health Centre of WA Winthrop Prof. Paul Abbott Director of Postgraduate Studies & Research Isolating Epithelial Cells of Malassez for Therapeutic Analysis Marisa de Pinho Background: Epithelial cells are notoriously very difficult to grow – need to enhance this growth Aim is to isolate, cultivate and purify epithelial cells of Malassez from human PDL fibroblasts Mediums to be investigated: EpiLife® (Invitrogen) – human epithelial cell medium Keratinocyte-SFM® (Invitrogen) – keratinocyte serum free medium KBM-Gold® (Lonza) – keratinocyte cell basal media MCB® – specific epithelial cell of Malassez medium Assoc. Prof. Tony Phan Tissue Engineering & Regeneration Fa-Ming Chen, Yan Jin. Tissue Engineering Part B: Reviews. April 2010, 16(2): 219-255. The SLURP family of Proteins Secreted mammalian Ly-6/Urokinase-type plasminogen activator receptor-Related Protein Lymphocyte Antigen 6 (Ly-6) Superfamily Function: cellular differentiation cell growth cell survival motility Glycosylphosphatidylinositol (GPI) -membrane linked Flexcell System Dr Danny Yang - PhD student Vacuum pump Flexcell CPU Tissue Regeneration in Oral Health: The effect of NGF and EGF on periodontal and pulp healing of replanted molars in a rat model Dr Estabelle Ang - Postdoc. Fellow Autotransplantation of Teeth Premolar Incisor site Winthrop Prof. Paul Abbott Managing Bone Resorption and External Inflammatory Root Resorption On referral 1 yr - Ca(OH)2 3 mths - Led. Winthrop Prof. Paul Abbott 6 mths - Led. Using Endodontic Medicaments to Treat Root Resorption Pre-operative RCF - 15 mths Winthrop Prof. Paul Abbott 4 yrs - Review Investigations into the Use of Interim Restorations During Endodontic Treatment Jensen A-L, Heffer RM, Hsu H-S, Abbott PV. Graduate Endodontic Program School of Dentistry University of Western Australia Willytec Chewing Simulator Willytec Chewing Simulator + Dye Results Structural Integrity Group Intact During mastication - 2 Debonded GIC 10 15 (60%) During de-mounting - 1 Band 25 0 Bacteria + Dye - 1 Dye only - 1 Dye only - 1 During access cavity prepn to test CW - 12 Bacteria + Dye - 1 Bacteria only - 3 Dye only - 2 Neither - 6 I. DEVELOPMENT OF FUNCTIONALLY-GRADED DENTAL BIOMATERIALS Prof. Paul Ichim in collaboration with W/Prof. Xiaozhi Hu (Mechanical Engineering, UWA) ARC Discovery grant 2011-2013 “Development of a hydroxyapatite-containing ceramic composite core dental implant system with effective variable elastic properties” II. DEVELOPMENT OF A NEW ENDODONTIC POST SYSTEM Prof. Paul Ichim in collaboration with Dr. Patrick Schmidlin (Faculty of Dentistry, Zurich). This project is funded by Ada Bartholomew research grant. III. DEVELOPMENT OF AN INDIRECT ASESSMENT OF CLINICAL COMPETENCY OF DENTAL STUDENTS Prof. Paul Ichim, A/Prof. Jennifer Bazen and W/Prof. Andrew Smith. External partners: School of Dentistry, University of Minessota. The project aims at delivering a competency-based clinical assessment in which the student performance is determined longitudinally by measuring the time spent by the faculty in assisting the student. Orthodontics Group Assoc. Prof. Mithran Goonewardene Histomorphometric Analysis of Bone Surrounding Loaded Microimplants Dr Angela Pathmanathan Aims: 1. To assess the changes in bone surrounding self-threaded and selftapping implants over time. 2. To assess which implants have a more effective response that can be used during orthodontics to achieve ideal movement of teeth over a shorter time period. Cephalometric investigation assessing the skeletal stability following Orthognathic Surgical Rotation of the Occlusal Plane Dr Rob Hamilton Manipulation of Occlusal Plane AIM Cephalometric investigation of the skeletal stability following orthognathic surgical treatment involving: Clockwise No-rotation Counterclockwise Student: Dr Chris Duigou Aims: 1. To investigate the treatment effects of using rapid maxillary expansion devices and facemasks on Class 3 patients. 2. To investigate candidate gene assessment to predict treatment response The Value of Digital Model Diagnostic Set-up in Treatment Planning Complex Interdisciplinary Treatment Cases. Roy Goonewardene Mike Razza Mithran Goonewardene Kevin Murray The value of a diagnostic set-up in treatment planning is generally acknowledged yet this has not been scientifically tested. Aim: To compare the efficacy of using both plaster and digital diagnostic casts for presentation of complex treatment plans to a group of restorative dentists. Moreover, the acceptability and value of using firstly a wax and plaster diagnostic set-up and secondly, digital models and setup will be evaluated. Relate years as a dentist/ IT familiarity and usage Paper/Film/Plaster + Plaster/Wax setup Repeat in Digital Format (on laptop computer) School of Dentistry Main Research Fields 1. Dental Public Health 7. Periodontics 2. Dental Traumatology 8. Oral Cancer 3. Education & Assessment 9. Oral Medicine & Oral Pathology 4. Simulation Teaching 10. Orthodontics 5. Endodontics 11. Oral & Maxillofacial Surgery 6. Materials Science 12. Tissue Regeneration and Auto-transplantation