Transcript Assessing Neurological Disability
Assessing Neurological Disability
Corina Azores-Macalintal, M.D., F.P.N.A
Questions
When is the patient neurologically disabled?
What kind of neurological disabilities does neurological diseases brings?
Disability
Definition: Inability to engage in any substantial gainful activity by reason of any medically determined physical or mental impairment(s) which can be expected to result to death or which has lasted or can be expected to last for a continuous period of time.
When is the patient neurologically disabled?
Mental/ cognitive Visual / auditory Motor Sensory Balance and Coordination Gait
Mental Disability
Language dysfunction (Aphasia) Executive dysfunction Memory dysfunction
Aphasia
Acquired impairment of comprehension and production of verbal language caused by brain damage.
Alexia and agraphia often co-exist with aphasia
Aphasia
Four areas of language functioning Auditory comprehension Repetition Fluency of verbal expression Confrontation naming
Non-fluent Broca’s Transcortical motor Global Mixed Transcortical Fluent Wernicke’s Transcortical sensory Conduction Anomic
Aphasia
Auditory comprehension Asyntactic Can be asyntactic Severe impairment and Retain prosody Like global Milder than global Asyntactic intact
Non-fluent Broca’s Transcortical motor Global Mixed Transcortical Fluent Wernicke’s Transcortical sensory Conduction Anomic
Aphasia
Verbal expression Agrammatism, aprosodia, apraxia of speech, poor repetition Poor initiation, elaboration, intact repetition,echolalia Limited to automatisms, stereotypies, poor repetition Limited spontaneous, intact repetition, echolalia Nonmeaningful logorrhea, anosognosia Intact repetition, echolalia Conduit d’approche, poor repetition Pauses for word retrieval, intact repetition
Non-fluent Broca’s Transcortical motor Global Mixed Transcortical Fluent Wernicke’s Transcortical sensory Conduction Anomic
Aphasia
Typical word retrieval errors Semantic, verbs worse than nouns No response, perseverations Stereotypies, semantic Stereotypies, semantic Neogolisms, semantic, phonemics Semantic, phonemic, circumlocutions Phonemics, semantic Circumlocutions, no response, semantic, nouns worse than verbs
Non-fluent Broca’s Transcortical motor Global Mixed Transcortical Fluent Wernicke’s Transcortical sensory Conduction Anomic
Aphasia
Left Hemisphere lesion locations Inf. Frontal, operculum Dosolateral frontal, or thalamus Large pre-rolandic + post rolandic Watershed/ extrasylvian cortex Superior temporal Temoral-parietal or degenerative Parietal, insula Inferior temporal or thalamus or degenerative
Executive Dysfunction
Impairments in initiation, intention, planning, sequencing, inhibition, flexibility, monitoring and various complex aspects of attention
Memory Dysfunction
MCI Dementia
Dementia
Memory impairment (learning and recall) One or more: Aphasia Apraxia Agnosia Dysexecutive function (planning, organizing, sequencing, abstracting) *** deficits of sufficient severity to affect social or occupational functioning
Limb Apraxia
Impaired ability to perform skilled, purposeful limb movements as a result of neurologic dysfunction ***excluding weakness, akinesia, abnormalities of tone or posture and movement disorders
Type Limb-kinetic Ideomotor
Limb Apraxia
Clinical features Impaired ability to make finem precise, independent finger movements Gesture production errors Ideational conceptual Impaired sequencing of tool use Content errors in tool use, errors in tool selection
Type Limb-kinetic Ideomotor Ideational conceptual
Limb Apraxia
Assessment tasks Rotate coin between thumb and fingers Gesture to command, gesture imitation Serial acts (e.g. fold letter place in envelope, seal, stamp) Tool-object matching (hammer and nail)
Assessment Tools
Mini Mental State Examination (MMSE)
Orientation Registration Attention and Calculation Recall Language
Neuropsychological Testing
Comprehensive examinations may be used to establish the existence and extent of compromise of brain function
Neuropsychological Testing
Cerebral dominance basic sensation and perception motor speed and coordination, attention and concentration, visual-motor function memory across verbal and visual modalities Receptive and expressive speech Higher-order linguistic operations Problem-solving Abstraction ability General intelligence
Neuropsychological Testing
Should include evaluating pathological features as: Emotional lability Abnormality of mood Impaired impulse control Passivity and apathy Inappropriate social behavior
Criteria for Organic Mental Disorder
A. Loss of specific cognitive abilities and medically documented persistence of at least one of the FF: Disorientation to time and place, or Memory impairment (short-term, intermediate, or long term), or Perceptual or thinking disturbances (e.g. hallucinations, delusions, or Change in personality, or Disturbance in mood, or Emotional lability (e.g. explosive temper outbursts, sudden crying…) and impairment of impulse control Loss of measured intellectual ability of at least 15 I.Q points from premorbid levels or severely impaired range on neuropsychological testing
And B. Resulting in at least two of the following Marked restriction of activities of daily living; or Marked difficulties in maintaining social functioning; or Marked difficulties in maintaining concentration, persistence, or pace; or Repeated episodes of decompensation, each of extended duration
Or C. Medically documented history of chronic organic mental disorder of at least 2 years and one of the following: Repeated episodes of decompensation, each of extended duration A residual disease process that has resulted in such marginal adjustment that even a minimal increase in mental demands or change in the environment would be predicted to cause the individual to decompensate
Current history of 1 or more years’ inability to function outside a highly supportive living arrangement, with an indication of continued need for such an arrangement
Presentations: Visual loss/blurring Visual field defects (anopsia)
Visual
Assessment Field testing Fundoscopy Visual acuity test (Snellen) VEP
Presentation: Deafness Tinnitus Dizziness
auditory
Assessment Weber, Rinne’s Audiogram BAER
Motor, sensory, balance, coordination and gait disabilities = disorganization of motor function
Disorganization of Motor function
In the form of paresis or paralysis, tremor or other involuntary movements, ataxia, sensory disturbances which may occur singly or in various combinations
Disorganization of Motor function
Assessment of impairment depends on the degree of interference with locomotion and/or interference with the use of fingers, hands and arms.
Assessment
Motor Strength Sensory Light touch, pressure, heat / cold, proprioception *** abnormal sensation as dysaesthesia, allodynia, hyperaesthesia
Assessment
Balance, coordination and gait Finger to nose test / heal to shin test Tandem walking
Category of Neurological Impairments
Convulsive Seizure
Degree of impairment Determined according to type, frequency, duration and sequelae At least 1 detailed description of a typical seizure Presence of associated signs/ symptoms Documentation with at least 1 EEG
Convulsive seizure
Only if impairment persists despite treatment Blood levels of anticonvulsant medications Compliance to anticonvulsant medication Idiosyncrasy in absorption or metabolism Use of alcohol or drug interactions
Convulsive Seizure
Category of impairments: Major motor seizures: (grand mal or psychomotor) Occuring > 1 / month, in spite of at least 3 months of prescribed treatment with: Daytime episodes Nocturnal episodes with residuals ( significantly interfering with activity during the day)
Convulsive Seizure
Minor motor seizures: (petit mal, psychomotor or focal) > 1x / week in spite of at least 3 months of prescribed treatment With alteration of consciousness and transient postictal manifestations of conventional behavior or significant interference with activity during the day
Vascular Accidents
(> 3 most post=vascular accident) Sensory or motor aphasia resulting in ineffective speech or communication; or Significant or persistent disorganization of motor function in two extremities, resulting in sustained disturbances of gross and dexterous movements, or gait and station.
Depends on the degree of interference with locomotion and/or interference with the use of fingers, hands and arms
Brain Tumors
Definitive diagnosis Histologically malignant tumor – pathological diagnosis alone will be the decisive criterion for severity and expected duration Other tumors – severity and duration of the impairment will be determined on the basis of symptoms, signs and pertinent laboratory findings Persistence of the tumor
Brain tumors
The site of primary, recurrent and metastatic lesion must be specified- in malignant neoplastic diseases Operative procedure or hospitalization with findings of surgery and results of pathologist’s gross and microscopic examination of tissues
Brain Tumors
Maligant gliomas( astrocytomas grades III IV, glioblastoma multiforme) medulloblastoma, epenymoblastoma, primary sarcoma) or Astrosarcoma (grades I-II), meningioma, pituitary tumors, oligodendroglioma, epndymoma, clivus chordoma and benign tumors
Brain Tumors
Assessment based on: Secondary Epilepsy, major or minor > 3 months of Sensory or motor aphasia Significant or persistent disorganization of motor function Secondary mental disorders
Parkinsonian syndrome
Significant rigidity, bradykinesia or tremor in two extremities which singly or in combination, result in sustained disturbance of gross and dexterous movements, or gait and station
Cerebral Palsy
IQ of 70 or less; or Abnormal behavior patterns, as destructive or emotional instability Significant interference in communication due to speech, hearing or visual defect; or Disorganization of motor functions
Spinal cord or nerve root lesions
Disorganization of motor function
Other Episodic conditions
Multiple sclerosis/ myasthenia gravis Frequency and duration of exacerbation Length of remissions Permanent residuals
Multiple Sclerosis
I. Disorganization of motor function Significant and persistent disorganization of motor function in two extremities, resulting in sustained disturbance of gross and dexterous movements, or gait and station
Multiple Sclerosis
II. Visual impairments Impairment of central visual acuity Contraction of peripheral visual fields in the better eye Loss of visual efficiency
Multiple Sclerosis
III. Mental impairments History and PE or laboratory tests demonstrate the presence of a specific organic factor judged to be etiologically related to the abnormal mental state and loss of previously acquired functional abilities
Multiple Sclerosis
IV. Significant reproducible fatigue of motor function with substantial muscle weakness on repetitive activity, demonstrated of PE with CNS correlation - use of assessment scale - evoke response tests during exercise
Myasthenia Gravis
Significant difficulty with speaking, swallowing or breathing while on prescribed therapy; or Significant motor weakness of muscles of extremities on repetitive activity against resistance while on prescribed therapy
Amyotrophic lateral sclerosis
Significant bulbar signs Disorganization of motor function
Anterior Poliomyelitis
Persistent difficulty with swallowing or breathing Unintelligible speech Disorganization of motor function
Muscular Dystrophy
Disorganization of motor function
Tabes Dorsalis
Tabetic crisis occuring more frequently than once monthly; or Unsteady, broad based or ataxic gait causing significant restriction of mobility substantiated by appropriate posterior column signs
Subacute combined cord Degeneration
Disorganization of motor function, not significantly improved by prescribed treatment
Degenerative disease
(Huntington’s chorea, Friedreich’s ataxia, and Spino cerebellar degeneration, Alzhiemer’s dementia…) Disorganization of motor function Chronic brain syndrome
Traumatic Brain Injury
May result in neurological and mental impairments with a wide variety of posttraumatic s/sx May need to defer adjudication of the claim at least 6 months post-injury
Traumatic Brain Injury
Evaluated according to: Secondary seizure Secondary motor or sensory aphasia Significant or persistent disorganization of motor function Cognitive dysfunction