Academic Centers Research Node of PECARN

( “ACORN” )

Supported by Project #U03 MC00001 from the Maternal and Child Health Bureau, Health Resources and Services Administration, Department of Health and Human Services

Who We Are

University of California, Davis Medical Center, University of California, Davis School of Medicine Children’s Hospital of Wisconsin, Medical College of Wisconsin Children’s Hospital of Philadelphia, University of Pennsylvania School of Medicine St. Louis Children’s Hospital, Washington University School of Medicine Primary Children’s Medical Center, University of Utah School of Medicine Children’s Hospital Medical Center, University of Cincinnati School of Medicine

University of California, Davis Medical Center University of California, Davis

Nathan Kuppermann, MD, MPH Chair, Department of Emergency Medicine, Professor of Emergency Medicine/Pediatrics Emily Kim, MPH ACORN Node Administrator Leah Tzimenatos, MD Assistant Clinical Professor Department of Emergency Medicine/Pediatrics James Holmes Jr., MD, MPH Professor of Emergency Medicine

Children’s Hospital of Wisconsin, Medical College of Wisconsin

Marc Gorelick, MD, MSCE Medical Director, Emergency Department, Professor of Pediatrics and Emergency Medicine

Children’s Hospital of Philadelphia, University of Pennsylvania

Elizabeth Alpern, MD, MSCE Assistant Professor of Pediatrics Kathy Shaw, MD, MSCE Division Chief, Pediatric Emergency Medicine, Professor of Pediatrics Evaline Alessandrini, MD, MSCE Associate Professor of Pediatrics

St. Louis Children’s Hospital, Washington University in St. Louis School of Medicine

David Jaffe, MD

Medical Director of Emergency Services, Professor of Pediatrics

American Family Children’s Hospital, University of Wisconsin School of Medicine & Public Health

Walton Schalick, MD, PhD Ethics Consultant Assistant Professor of Bioethics, Medical History, Pediatrics, Orthopedics & Rehabilitation, History of Science, and History University of Wisconsin-Madison

Primary Children’s Medical Center, University of Utah

Douglas Nelson, MD Professor of Pediatrics Associate Chief, Pediatric Emergency Medicine

Cincinnati Children’s Hospital Medical Center, University of Cincinnati College of Medicine

Richard Ruddy, MD Director, Division of Emergency Medicine Professor of Clinical Pediatrics

Where We Are Located

ACORN Organizational Structure

ACORN Proposal Generation & Review Process

ACORN Strengths

• ACORN investigators have high-level training and expertise in epidemiology/biostatistics/ethics • ACORN members are senior-level PEM investigators with substantial research, grant writing and publication experience, and leadership in the field of PEM • ACORN research proposals are subject to a rigorous internal review process with participation by all core ACORN investigators

ACORN-lead Research

• • • • • • •

Ongoing Projects:

Randomized Trial of Oral Dexamethasone in Acute

Bronchiolitis (subanalyses ongoing)

PECARN Core Data Project Head Injury Project Cervical Spine Injury Project Intra-abdominal Injury Project Patient Safety Project Quality Measures Project

ACORN-lead Research

• • • • • •

Future Research Endeavors:

Randomized Trial of IV Magnesium for Treatment of Pain Crises in Sickle Cell Disease Randomized Trial of C-Spine Immobilization in Children at Low-Risk for C-Spine Injury Safety of Emergency Department Procedural Sedation Medical Error Reduction in Pediatric Emergency Medicine RCT of Fluid Therapy for DKA Knowledge Translation Research of Information Generated by Completed PECARN Research

Concluding Statement

The ACORN Node of PECARN is committed to applying our strengths and expertise to the study of the prevention and treatment of acutely ill and injured children. We will maintain strong collaborations with all other Nodes of PECARN, the MCHB/EMSC, and EMSC practitioners. We are confident that the strong commitment of all the Nodes of PECARN will insure the success of this robust and exciting network.